P10128 (RS5_MYCCT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S5

Gene names

Name:	rpsE
Ordered Locus Names:	MCAP_0679

Organism

Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154) [Complete proteome] [HAMAP]

Taxonomic identifier

340047 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma mycoides group › Mycoplasma capricolum › Mycoplasma capricolum subsp. capricolum

Protein attributes

Sequence length	250 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	With S4 and S12 plays an important role in translational accuracy By similarity. HAMAP-Rule MF_01307 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body By similarity. HAMAP-Rule MF_01307
Subunit structure	Part of the 30S ribosomal subunit. Contacts proteins S4 and S8 By similarity.
Domain	The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity. HAMAP-Rule MF_01307
Sequence similarities	Belongs to the ribosomal protein S5P family. Contains 1 S5 DRBM domain.
Sequence caution	The sequence ABC01587.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 250	250	30S ribosomal protein S5 HAMAP-Rule MF_01307		PRO_0000131545
Regions
	Domain	45 – 108	64	S5 DRBM
Experimental info
	Sequence conflict	114	1	T → A in CAA29721. Ref.1
	Sequence conflict	118 – 119	2	EV → WS in CAA29721. Ref.1
	Sequence conflict	147	1	A → S in CAA29721. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P10128 [UniParc]. Last modified March 21, 2006. Version 2. Checksum: 5E1EDA6F7E15FF11	FASTA	250	27,371
	10 20 30 40 50 60 MNVVETSSEM NSNVEKASTP KQENNKRFER KSRPSSRQKV VKDEFEEKVV TIRRVTKVTK 70 80 90 100 110 120 GGRHFRFAAV VVVGNKKGLV GMGTGKANEV PEAIKKAIKE AKKNLVSVTL RNTTVPHEVL 130 140 150 160 170 180 GTFGAGKILI KPAKVGTGII AGGPARAVIE LSGISDVYAK SLGSNNAINM IRATFEGLSS 190 200 210 220 230 240 MQTLKRVQEL RYGKTFDKQK VALVEKTAET KNFEKKPPKS TTKKMASKKI EKEDVIAEPM 250 IKNEAENSAE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The ribosomal protein gene cluster of Mycoplasma capricolum." Ohkubo S., Muto A., Kawauchi Y., Yamao F., Osawa S. Mol. Gen. Genet. 210:314-322(1987) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O., Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: California kid / ATCC 27343 / NCTC 10154.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X06414 Genomic DNA. Translation: CAA29721.1. CP000123 Genomic DNA. Translation: ABC01587.1. Different initiation.
PIR	R3YM5C. S02848.
RefSeq	YP_424643.1. NC_007633.1.
3D structure databases
ProteinModelPortal	P10128.
SMR	P10128. Positions 42-182.
ModBase	Search...
Protein-protein interaction databases
STRING	340047.MCAP_0679.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABC01587; ABC01587; MCAP_0679.
GeneID	3828832.
KEGG	mcp:MCAP_0679.
PATRIC	20005835. VBIMycCap130493_0672.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0098.
HOGENOM	HOG000072595.
KO	K02988.
ProtClustDB	PRK00550.
Family and domain databases
Gene3D	3.30.160.20. 1 hit. 3.30.230.10. 1 hit.
HAMAP	MF_01307_B. Ribosomal_S5_B.
InterPro	IPR014720. dsRNA-bd-like_dom. IPR000851. Ribosomal_S5. IPR005712. Ribosomal_S5_bac-type. IPR005324. Ribosomal_S5_C. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR013810. Ribosomal_S5_N. IPR018192. Ribosomal_S5_N_CS. [Graphical view]
PANTHER	PTHR13718. PTHR13718. 1 hit.
Pfam	PF00333. Ribosomal_S5. 1 hit. PF03719. Ribosomal_S5_C. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR01021. rpsE_bact. 1 hit.
PROSITE	PS00585. RIBOSOMAL_S5. 1 hit. PS50881. S5_DSRBD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS5_MYCCT

Accession

Primary (citable) accession number: P10128
Secondary accession number(s): Q2SRH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	March 21, 2006
Last modified:	May 1, 2013
This is version 86 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program