Fibritin - Enterobacteria phage T4

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P10104 (WAC_BPT4) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 87. History...

Clusters with 100%, 90%, 50% identity |

Documents (1) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Fibritin

Alternative name(s):
Collar protein
Whisker antigen control protein

Gene names

Name:

wac

Organism

Enterobacteria phage T4 (Bacteriophage T4) [Reference proteome]

Taxonomic identifier

10665 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Caudovirales › Myoviridae › Tevenvirinae › T4likevirus ›

Virus host

Escherichia coli [TaxID: 562]

Protein attributes

Sequence length	487 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').
Subunit structure	Homotrimer.
Domain	The central domain consists of 12 alpha-helical domains (19-40 residues long) with coiled-coil structural patterns.

Ontologies

Keywords
Domain	Coiled coil
Molecular function	Chaperone
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

Removed; by host

Chain

2 – 487

486

Fibritin

PRO_0000165075

Experimental info

Sequence conflict

358

P → H in CAA31379. Ref.4

Sequence conflict

479

F → L in CAA31379. Ref.4

Sequence conflict

481

S → P Ref.1

Secondary structure

487

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

P10104 [UniParc].

Last modified January 23, 2007. Version 5.
Checksum: 253A30F0F0ED13B5
Show »

FASTA

487

51,872

        10         20         30         40         50         60 
MTDIVLNDLP FVDGPPAEGQ SRISWIKNGE EILGADTQYG SEGSMNRPTV SVLRNVEVLD 

        70         80         90        100        110        120 
KNIGILKTSL ETANSDIKTI QGILDVSGDI EALAQIGINK KDISDLKTLT SEHTEILNGT 

       130        140        150        160        170        180 
NNTVDSILAD IGPFNAEANS VYRTIRNDLL WIKRELGQYT GQDINGLPVV GNPSSGMKHR 

       190        200        210        220        230        240 
IINNTDVITS QGIRLSELET KFIESDVGSL TIEVGNLREE LGPKPPSFSQ NVYSRLNEID 

       250        260        270        280        290        300 
TKQTTVESDI SAIKTSIGYP GNNSIITSVN TNTDNIASIN LELNQSGGIK QRLTVIETSI 

       310        320        330        340        350        360 
GSDDIPSSIK GQIKDNTTSI ESLNGIVGEN TSSGLRANVS WLNQIVGTDS SGGQPSPPGS 

       370        380        390        400        410        420 
LLNRVSTIET SVSGLNNAVQ NLQVEIGNNS AGIKGQVVAL NTLVNGTNPN GSTVEERGLT 

       430        440        450        460        470        480 
NSIKANETNI ASVTQEVNTA KGNISSLQGD VQALQEAGYI PEAPRDGQAY VRKDGEWVFL 


STFLSPA

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide and deduced amino acid sequence of bacteriophage T4 gene wac." Prilipov A.G., Selivanov N.A., Nikolaeva L.I., Mesyanzhinov V.V. Nucleic Acids Res. 16:10361-10361(1988) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: D.
[2]	"Fibritin encoded by bacteriophage T4 gene wac has a parallel triple-stranded alpha-helical coiled-coil structure." Efimov V.P., Nepluev I.V., Sobolev B.N., Zurabishvili T.G., Schulthess T., Lustig A., Engel J., Haener M., Aebi U., Venyaminov S.Y., Potekhin S.A., Mesyanzhinov V.V. J. Mol. Biol. 242:470-486(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: D.
[3]	Mesyanzhinov V.V. Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION TO 358 AND 479. Strain: D.
[4]	"Bacteriophage T4 genome." Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W. Microbiol. Mol. Biol. Rev. 67:86-156(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"Nucleotide sequences of bacteriophage T4 genes 13, 14 and 15." Selivanov N.A., Prilipov A.G., Mesyanzhinov V.V. Nucleic Acids Res. 17:3583-3583(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 480-487. Strain: D.
[6]	"Nucleotide and deduced amino acid sequence of bacteriophage T4 gene 12." Selivanov N.A., Prilipov A.G., Mesyanzhinov V.V. Nucleic Acids Res. 16:2334-2334(1988) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-14. Strain: D.
[7]	"The wac gene product of bacteriophage T4 contains coiled-coil structural patterns." Sobolev B.N., Mesyanzhinov V.V. J. Biomol. Struct. Dyn. 8:953-965(1991) [PubMed] [Europe PMC] [Abstract] Cited for: TOPOLOGY.
[8]	"Structure of bacteriophage T4 fibritin: a segmented coiled coil and the role of the C-terminal domain." Tao Y., Strelkov S.V., Mesyanzhinov V.V., Rossmann M.G. Structure 5:789-798(1997) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 369-487.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

X12888 Genomic DNA. Translation: CAA31379.1.
AF158101 Genomic DNA. Translation: AAD42679.1.
X14868 Genomic DNA. Translation: CAA33006.1.
X06792 Genomic DNA. Translation: CAA29952.1.

PIR

FIBPT4. S01917.

RefSeq

NP_049771.1. NC_000866.4.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1AA0	X-ray	2.20	A	372-484	[»]
1AVY	X-ray	1.85	A/B/C	414-487	[»]
1OX3	X-ray	2.00	A	3-484	[»]
1RFO	NMR	-	A/B/C	458-484	[»]
1V1H	X-ray	1.90	A/B/C/D/E/F	458-483	[»]
1V1I	X-ray	1.90	A/B/C	458-483	[»]
2BSG	electron microscopy	15.00	A/B/C	2-486	[»]
2IBL	X-ray	1.32	A	2-80	[»]
2KBL	NMR	-	A	458-484	[»]
3A1M	X-ray	2.00	A/B/C/D/E/F	458-484	[»]
3J2O	electron microscopy	25.00	A/B/C/D/E/F	2-487	[»]

ProteinModelPortal

P10104.

SMR

P10104. Positions 3-81, 372-484.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1258630.

Phylogenomic databases

ProtClustDB

PHA2607.

Family and domain databases

Gene3D

1.20.5.320. 2 hits.

InterPro

IPR012284. Fibritin/6PGD_C-extension.
IPR012473. Fibritin_C.
[Graphical view]

Pfam

PF07921. Fibritin_C. 1 hit.
[Graphical view]

PRINTS

PR01880. FIBRITIN.

ProtoNet

Search...

Other

EvolutionaryTrace

P10104.

Entry information

Entry name

WAC_BPT4

Accession

Primary (citable) accession number: P10104
Secondary accession number(s): O10628, Q9T0U8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 87 of the entry and version 5 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Experimental info

Secondary structure

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Other

Entry information

Relevant documents