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P10099

- LYS8_ECOLX

UniProt

P10099 - LYS8_ECOLX

Protein

Lysis protein for colicin E8

Gene

lys

Organism
Escherichia coli
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Lysis proteins are required for both colicin release and partial cell lysis.

    GO - Biological processi

    1. cytolysis Source: InterPro
    2. pathogenesis Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lysis protein for colicin E8
    Gene namesi
    Name:lys
    Encoded oniPlasmid ColE80 Publication
    OrganismiEscherichia coli
    Taxonomic identifieri562 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

    Subcellular locationi

    Cell outer membrane Curated; Lipid-anchor PROSITE-ProRule annotation

    GO - Cellular componenti

    1. cell outer membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell outer membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919PROSITE-ProRule annotationAdd
    BLAST
    Chaini20 – 4728Lysis protein for colicin E8PRO_0000005688Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Lipidationi20 – 201N-palmitoyl cysteinePROSITE-ProRule annotation
    Lipidationi20 – 201S-diacylglycerol cysteinePROSITE-ProRule annotation

    Keywords - PTMi

    Lipoprotein, Palmitate

    Family & Domainsi

    Keywords - Domaini

    Signal

    Family and domain databases

    InterProiIPR003059. Lysis_col.
    [Graphical view]
    PfamiPF02402. Lysis_col. 1 hit.
    [Graphical view]
    PRINTSiPR01297. LYSISCOLICIN.
    PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P10099-1 [UniParc]FASTAAdd to Basket

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    MKKITGIILL LLAVIILAAC QANYIRDVQG GTVSPSSTAE VTGLATQ      47
    Length:47
    Mass (Da):4,844
    Last modified:July 1, 1989 - v1
    Checksum:i691E149A8A056B38
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M21404 Genomic DNA. Translation: AAA23075.1.
    X06119 Genomic DNA. Translation: CAA29493.1.
    PIRiC28184. ZHECE8.
    RefSeqiWP_001314446.1. NC_012882.1.
    YP_002993421.1. NC_012882.1.

    Genome annotation databases

    GeneIDi8094684.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M21404 Genomic DNA. Translation: AAA23075.1 .
    X06119 Genomic DNA. Translation: CAA29493.1 .
    PIRi C28184. ZHECE8.
    RefSeqi WP_001314446.1. NC_012882.1.
    YP_002993421.1. NC_012882.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8094684.

    Family and domain databases

    InterProi IPR003059. Lysis_col.
    [Graphical view ]
    Pfami PF02402. Lysis_col. 1 hit.
    [Graphical view ]
    PRINTSi PR01297. LYSISCOLICIN.
    PROSITEi PS51257. PROKAR_LIPOPROTEIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequences from the colicin E8 operon: homology with plasmid ColE2-P9."
      Uchimura T., Lau P.C.K.
      Mol. Gen. Genet. 209:489-493(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Colicin E8, a DNase which indicates an evolutionary relationship between colicins E2 and E3."
      Toba M., Masaki H., Ohta T.
      J. Bacteriol. 170:3237-3242(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiLYS8_ECOLX
    AccessioniPrimary (citable) accession number: P10099
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: July 1, 1989
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Plasmid

    External Data

    Dasty 3