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P10099 (LYS8_ECOLX) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Lysis protein for colicin E8
Gene names
Name:lys
Encoded onPlasmid ColE8
OrganismEscherichia coli
Taxonomic identifier562 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length47 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existencePredicted

General annotation (Comments)

Function

Lysis proteins are required for both colicin release and partial cell lysis.

Subcellular location

Cell outer membrane; Lipid-anchor Potential.

Ontologies

Keywords
   Cellular componentCell outer membrane
Membrane
   DomainSignal
   PTMLipoprotein
Palmitate
   Technical termPlasmid
Gene Ontology (GO)
   Biological_processcytolysis

Inferred from electronic annotation. Source: InterPro

pathogenesis

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcell outer membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 4728Lysis protein for colicin E8
PRO_0000005688

Amino acid modifications

Lipidation201N-palmitoyl cysteine Potential
Lipidation201S-diacylglycerol cysteine Potential

Sequences

Sequence LengthMass (Da)Tools
P10099 [UniParc].

Last modified July 1, 1989. Version 1.
Checksum: 691E149A8A056B38

FASTA474,844
        10         20         30         40 
MKKITGIILL LLAVIILAAC QANYIRDVQG GTVSPSSTAE VTGLATQ 

« Hide

References

[1]"Nucleotide sequences from the colicin E8 operon: homology with plasmid ColE2-P9."
Uchimura T., Lau P.C.K.
Mol. Gen. Genet. 209:489-493(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Colicin E8, a DNase which indicates an evolutionary relationship between colicins E2 and E3."
Toba M., Masaki H., Ohta T.
J. Bacteriol. 170:3237-3242(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M21404 Genomic DNA. Translation: AAA23075.1.
X06119 Genomic DNA. Translation: CAA29493.1.
PIRZHECE8. C28184.
RefSeqYP_002993421.1. NC_012882.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8094684.

Family and domain databases

InterProIPR003059. Lysis_col.
[Graphical view]
PfamPF02402. Lysis_col. 1 hit.
[Graphical view]
PRINTSPR01297. LYSISCOLICIN.
PROSITEPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLYS8_ECOLX
AccessionPrimary (citable) accession number: P10099
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program