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P10081 (IF4A_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 171. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (6) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP-dependent RNA helicase eIF4A

EC=3.6.4.13
Alternative name(s):
Eukaryotic initiation factor 4A
Short name=eIF-4A
Stimulator factor I 37 kDa component
Translation initiation factor 1/2
p37
Gene names
Name:TIF1
Synonyms:TIF41A
Ordered Locus Names:YKR059W
AND
Name:TIF2
Synonyms:TIF41B
Ordered Locus Names:YJL138C
ORF Names:J0660
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. Ref.10 Ref.11 Ref.13 Ref.15 Ref.16 Ref.17

Catalytic activity

ATP + H2O = ADP + phosphate.

Subunit structure

Component of the eIF4F complex, which composition varies with external and internal environmental conditions. It is composed of at least eIF4A (TIF1/TIF2), eIF4E (TIF45) and eIF4G (TIF4631 or TIF4632) By similarity. Interacts with eIF4G1/TIF4631 and eIF4G2/TIF4632. Ref.15 Ref.16

Subcellular location

Cytoplasm Ref.18.

Domain

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. Ref.17

Miscellaneous

TIF1 and TIF2 code for the same protein.

Present with 106000 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the DEAD box helicase family. eIF4A subfamily.

Contains 1 helicase ATP-binding domain.

Contains 1 helicase C-terminal domain.

Biophysicochemical properties

Kinetic parameters:

KM=470 µM for ATP Ref.13 Ref.17

Vmax=2.6 pmol/sec/µg enzyme for ATP

pH dependence:

Optimum pH is 6.0.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

TIF4631P399357EBI-9017,EBI-9002

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed
Chain2 – 395394ATP-dependent RNA helicase eIF4A
PRO_0000054968

Regions

Domain53 – 222170Helicase ATP-binding
Domain233 – 394162Helicase C-terminal
Nucleotide binding66 – 738ATP
Motif22 – 5029Q motif
Motif170 – 1734DEAD box

Amino acid modifications

Modified residue21N-acetylserine Ref.14 Ref.23
Modified residue731Phosphothreonine Ref.22
Modified residue771Phosphoserine Ref.22
Modified residue1291Phosphoserine Ref.21
Modified residue1461Phosphothreonine Ref.20 Ref.21 Ref.22

Experimental info

Mutagenesis241F → A: Lethal in vivo and reduces ATP binding and ATPase activity in vitro. Ref.17
Mutagenesis421F → A: Slow growth in vivo and reduces ATP binding and ATPase activity in vitro. Ref.17
Mutagenesis461S → A: Reduces ATP binding and ATPase activity in vitro. Ref.17
Mutagenesis491Q → A: Reduces ATP binding and ATPase activity in vitro. Ref.17
Mutagenesis491Q → E: Increases about 3-fold ATP binding but reduces about 2-fold ATPase activity in vitro. Ref.17
Mutagenesis661A → D: Slow growth. Ref.12 Ref.13
Mutagenesis661A → V: Lethal and dominant negative if overexpressed in vivo. Impairs ATP hydrolysis, RNA-helicase and translation activity in vitro. Ref.12 Ref.13
Mutagenesis721K → A: Lethal in vivo and reduces ATP binding and ATPase activity in vitro. Ref.17
Mutagenesis791A → V in TIF1-1; no growth at 36 degrees Celsius. Ref.12
Mutagenesis1261G → D: Lethal. Ref.12
Mutagenesis1271G → D: Slow growth. Ref.12
Mutagenesis1451G → D: Lethal. Ref.12
Mutagenesis1451G → S: Slow growth. Ref.12
Mutagenesis1701D → E: Lethal. Ref.12
Mutagenesis1731D → H: Lethal. Ref.12
Mutagenesis3111S → F: Slow growth. Ref.12
Mutagenesis3471R → E, G, I, S or T: Lethal and dominant negative if overexpressed. Ref.12

Secondary structure

............................................................... 395
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P10081 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 19D8C133C815DD48

FASTA39544,697
        10         20         30         40         50         60 
MSEGITDIEE SQIQTNYDKV VYKFDDMELD ENLLRGVFGY GFEEPSAIQQ RAIMPIIEGH 

        70         80         90        100        110        120 
DVLAQAQSGT GKTGTFSIAA LQRIDTSVKA PQALMLAPTR ELALQIQKVV MALAFHMDIK 

       130        140        150        160        170        180 
VHACIGGTSF VEDAEGLRDA QIVVGTPGRV FDNIQRRRFR TDKIKMFILD EADEMLSSGF 

       190        200        210        220        230        240 
KEQIYQIFTL LPPTTQVVLL SATMPNDVLE VTTKFMRNPV RILVKKDELT LEGIKQFYVN 

       250        260        270        280        290        300 
VEEEEYKYEC LTDLYDSISV TQAVIFCNTR RKVEELTTKL RNDKFTVSAI YSDLPQQERD 

       310        320        330        340        350        360 
TIMKEFRSGS SRILISTDLL ARGIDVQQVS LVINYDLPAN KENYIHRIGR GGRFGRKGVA 

       370        380        390 
INFVTNEDVG AMRELEKFYS TQIEELPSDI ATLLN 

« Hide

References

« Hide 'large scale' references
[1]"Sequence of the genes TIF1 and TIF2 from Saccharomyces cerevisiae coding for a translation initiation factor."
Linder P., Slonimski P.P.
Nucleic Acids Res. 16:10359-10359(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (TIF1 AND TIF2).
Strain: CD11/B1830/50.
[2]"An essential yeast protein, encoded by duplicated genes TIF1 and TIF2 and homologous to the mammalian translation initiation factor eIF-4A, can suppress a mitochondrial missense mutation."
Linder P., Slonimski P.P.
Proc. Natl. Acad. Sci. U.S.A. 86:2286-2290(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (TIF1 AND TIF2).
Strain: CD11/B1830/50.
[3]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (TIF1).
Strain: ATCC 204508 / S288c.
[4]"Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI."
Katsoulou C., Tzermia M., Tavernarakis N., Alexandraki D.
Yeast 12:787-797(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (TIF2).
Strain: ATCC 96604 / S288c / FY1679.
[5]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (TIF2).
Strain: ATCC 204508 / S288c.
[6]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION (TIF1 AND TIF2).
Strain: ATCC 204508 / S288c.
[7]"Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae."
Cheng C., Mu J., Farkas I., Huang D., Goebl M.G., Roach P.J.
Mol. Cell. Biol. 15:6632-6640(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-93 (TIF2).
[8]"The Saccharomyces cerevisiae RPB4 gene is tightly linked to the TIF2 gene."
Foreman P.K., Davis R.W., Sachs A.B.
Nucleic Acids Res. 19:2781-2781(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 307-395 (TIF2).
[9]"The 66 kDa component of yeast SFI, stimulatory factor I, is hsp60."
Smiley J.K., Brown W.C., Campbell J.L.
Nucleic Acids Res. 20:4913-4918(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 332-340; 342-347 AND 378-391.
[10]"Translation in Saccharomyces cerevisiae: initiation factor 4A-dependent cell-free system."
Blum S., Mueller M., Schmid S.R., Linder P., Trachsel H.
Proc. Natl. Acad. Sci. U.S.A. 86:6043-6046(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[11]"Translation initiation factor-dependent extracts from Saccharomyces cerevisiae."
Altmann M., Blum S., Pelletier J., Sonenberg N., Wilson T.M., Trachsel H.
Biochim. Biophys. Acta 1050:155-159(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[12]"Translation initiation factor 4A from Saccharomyces cerevisiae: analysis of residues conserved in the D-E-A-D family of RNA helicases."
Schmid S.R., Linder P.
Mol. Cell. Biol. 11:3463-3471(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION, MUTAGENESIS OF ALA-66; ALA-79; GLY-126; GLY-127; GLY-145; ASP-170; ASP-173; SER-311 AND ARG-347.
[13]"ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae."
Blum S., Schmid S.R., Pause A., Buser P., Linder P., Sonenberg N., Trachsel H.
Proc. Natl. Acad. Sci. U.S.A. 89:7664-7668(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ALA-66.
[14]"Proteome studies of Saccharomyces cerevisiae: identification and characterization of abundant proteins."
Garrels J.I., McLaughlin C.S., Warner J.R., Futcher B., Latter G.I., Kobayashi R., Schwender B., Volpe T., Anderson D.S., Mesquita-Fuentes R., Payne W.E.
Electrophoresis 18:1347-1360(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION AT SER-2.
[15]"Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionally."
Neff C.L., Sachs A.B.
Mol. Cell. Biol. 19:5557-5564(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, INTERACTION WITH TIF4631 AND TIF4632.
[16]"Interaction of translation initiation factor eIF4G with eIF4A in the yeast Saccharomyces cerevisiae."
Dominguez D., Altmann M., Benz J., Baumann U., Trachsel H.
J. Biol. Chem. 274:26720-26726(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, INTERACTION WITH TIF4631.
[17]"The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis."
Tanner N.K., Cordin O., Banroques J., Doere M., Linder P.
Mol. Cell 11:127-138(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, DOMAIN, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF PHE-24; PHE-42; SER-46; GLN-49 AND LYS-72.
[18]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[19]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[20]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-146, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ADR376.
[21]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-129 AND THR-146, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[22]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-73; SER-77 AND THR-146, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[23]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[24]"Crystallographic structure of the amino terminal domain of yeast initiation factor 4A, a representative DEAD-box RNA helicase."
Johnson E.R., McKay D.B.
RNA 5:1526-1534(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 3-225.
[25]"Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae -- the prototype of the DEAD box protein family."
Benz J., Trachsel H., Baumann U.
Structure 7:671-679(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 10-233.
[26]"Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase."
Caruthers J.M., Johnson E.R., McKay D.B.
Proc. Natl. Acad. Sci. U.S.A. 97:13080-13085(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 231-395.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X12813 Genomic DNA. Translation: CAA31301.1.
X12814 Genomic DNA. Translation: CAA31302.1.
X58099 Genomic DNA. Translation: CAA41110.1.
X87371 Genomic DNA. Translation: CAA60817.1.
Z49413 Genomic DNA. Translation: CAA89433.1.
U25436 Genomic DNA. Translation: AAA91645.1.
Z28284 Genomic DNA. Translation: CAA82138.1.
BK006943 Genomic DNA. Translation: DAA08662.1.
BK006944 Genomic DNA. Translation: DAA09210.1.
PIRFIBY1. S05835.
RefSeqNP_012397.1. NM_001181571.1.
NP_012985.3. NM_001179849.3.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1FUKX-ray1.75A231-395[»]
1FUUX-ray2.50A/B2-395[»]
1QDEX-ray2.00A9-232[»]
1QVAX-ray2.50A2-224[»]
2VSOX-ray2.60A/B1-395[»]
2VSXX-ray2.80A/B1-395[»]
ProteinModelPortalP10081.
SMRP10081. Positions 12-395.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33619. 156 interactions.
34190. 123 interactions.
DIPDIP-4571N.
IntActP10081. 51 interactions.
MINTMINT-8285693.
STRING4932.YKR059W.

2D gel databases

SWISS-2DPAGEP10081.

Proteomic databases

PaxDbP10081.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL138C; YJL138C; YJL138C.
YKR059W; YKR059W; YKR059W.
GeneID853303.
853933.
KEGGsce:YJL138C.
sce:YKR059W.

Organism-specific databases

SGDS000001767. TIF1.
S000003674. TIF2.

Phylogenomic databases

eggNOGCOG0513.
GeneTreeENSGT00740000115544.
HOGENOMHOG000268797.
KOK03257.
OMANACNHLA.
OrthoDBEOG7FNCJ0.

Enzyme and pathway databases

BioCycYEAST:G3O-31584-MONOMER.
YEAST:G3O-32027-MONOMER.
SABIO-RKP10081.

Gene expression databases

GenevestigatorP10081.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
InterProIPR011545. DNA/RNA_helicase_DEAD/DEAH_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 2 hits.
PROSITEPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP10081.
NextBio973627.

Entry information

Entry nameIF4A_YEAST
AccessionPrimary (citable) accession number: P10081
Secondary accession number(s): D6VW46
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 171 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Translation initiation factors

List of translation initiation factor entries