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Protein

Zinc finger protein 26

Gene

Zfp26

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri191 – 213C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri246 – 268C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 296C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri302 – 324C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri498 – 520C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri526 – 548C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 576C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri582 – 604C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri610 – 632C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri638 – 660C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri666 – 688C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri694 – 716C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri722 – 744C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri750 – 772C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri778 – 800C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri806 – 828C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri834 – 856C2H2-type 23; degeneratePROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 26
Short name:
Zfp-26
Alternative name(s):
Protein mKR3
Gene namesi
Name:Zfp26
Synonyms:Kiaa4196, Mkr3, Zfp-26
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:99173. Zfp26.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000472871 – 861Zinc finger protein 26Add BLAST861

Proteomic databases

MaxQBiP10076.
PaxDbiP10076.
PRIDEiP10076.

PTM databases

iPTMnetiP10076.
PhosphoSitePlusiP10076.

Expressioni

Gene expression databases

BgeeiENSMUSG00000063108.
CleanExiMM_ZFP26.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000124075.

Structurei

3D structure databases

ProteinModelPortaliP10076.
SMRiP10076.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 80KRABPROSITE-ProRule annotationAdd BLAST72

Sequence similaritiesi

Contains 23 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 KRAB domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri191 – 213C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri246 – 268C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 296C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri302 – 324C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri498 – 520C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri526 – 548C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 576C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri582 – 604C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri610 – 632C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri638 – 660C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri666 – 688C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri694 – 716C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri722 – 744C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri750 – 772C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri778 – 800C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri806 – 828C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri834 – 856C2H2-type 23; degeneratePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiP10076.
KOiK09228.
PhylomeDBiP10076.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 22 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 9 hits.
PF13912. zf-C2H2_6. 4 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 23 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 22 hits.
PS50157. ZINC_FINGER_C2H2_2. 23 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P10076-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METQQVDAVT FEDVAVDFTQ EEWTSLDPVQ RNLYRDVMLE NYQNLATVGG
60 70 80 90 100
QMFKPSLISW LEKKVELTVI EQGILQEWEM HLKTKRTALQ QDRFWSDMSN
110 120 130 140 150
GMQLGREHSG GEPGDPVQVG AVFSEDSCPQ THSSTSNTGN TFACNLDGKD
160 170 180 190 200
FQPLLKETST EENIVQLNQC VKPLIFTPDV SQKKCTPEKS VECSDCGETF
210 220 230 240 250
VNQLELQTHS SSHREKNIHK SEECGQASTH PISHGGHVIP TEKKYYECKK
260 270 280 290 300
CEKFFTHPVY LNIHMQSHTV EKPYDCKECG KAFTERSSLI VHLRQHTREK
310 320 330 340 350
SYECKECGKT FIQPSRLTEH MRSHTGEKPY QCDQCGNAFA SSSYLTTHLR
360 370 380 390 400
THTGEKPFEC NICGKAFTRS SYLLGHIRTH TGEKPYECKV CGKAFSGRSW
410 420 430 440 450
LTIHLRKHTG ERPYPCTECE KAFTSFAQLT EHIKTHTGEK PFRCKVCART
460 470 480 490 500
FRNSSCLKTH FRIHTGIKPY KCNYCGKAFT ARSGLTKHVL IHNGEKPYEC
510 520 530 540 550
KECGKAFSTS SGLVEHIRIH TGEKPFECYQ CGKALAHSSS LVGHLRTHTG
560 570 580 590 600
EKPFECNQCD KTFTRSSYLR IHMRTHTGEK PYECKECGKT FPERSCLTKH
610 620 630 640 650
IRTHTGERPY ECKECGKGFI SFAQLTVHIK THSSERPFQC KVCTKSFRNS
660 670 680 690 700
SSLETHFRIH TGVKPYKCSY CGKAFTARSG LTIHLRNHTG EKSYACQECG
710 720 730 740 750
KAFSTSSGLI AHIRSHKGEK PFECDHCGKA FASSSYLNVH LKIHTGEKPF
760 770 780 790 800
QCTVCGKTFT CSSYLPVHMR THTGEKPFQC IICGKSFLWS SYLRVHMRIH
810 820 830 840 850
TGEKPYVCQY CGKAFTEHSG LNKHLRKHTG EKPYEYKECG ENFTTSADAN
860
EHETPHWGEN L
Length:861
Mass (Da):97,989
Last modified:January 9, 2007 - v2
Checksum:i24E87864BCCD83A1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti460H → N in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti460H → N in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti476G → W in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti476G → W in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti536A → V in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti536A → V in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti616G → D in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti616G → D in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti681L → P in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti681L → P in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti732A → P in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti732A → P in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti751Q → R in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti751Q → R in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti775 – 776EK → GR in CAA31105 (PubMed:3143103).Curated2
Sequence conflicti775 – 776EK → GR in AAA37118 (PubMed:3143103).Curated2
Sequence conflicti779Q → R in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti779Q → R in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti785K → R in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti785K → R in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti859 – 860EN → DL in CAA31105 (PubMed:3143103).Curated2
Sequence conflicti859 – 860EN → DL in AAA37118 (PubMed:3143103).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK141740 mRNA. Translation: BAE24816.1.
AK220539 mRNA. Translation: BAD90314.1.
M36514 mRNA. Translation: AAA37118.1.
X12592 mRNA. Translation: CAA31105.1.
PIRiS03677.
RefSeqiNP_035883.2. NM_011753.3.
UniGeneiMm.107441.

Genome annotation databases

GeneIDi22688.
KEGGimmu:22688.
UCSCiuc009oil.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK141740 mRNA. Translation: BAE24816.1.
AK220539 mRNA. Translation: BAD90314.1.
M36514 mRNA. Translation: AAA37118.1.
X12592 mRNA. Translation: CAA31105.1.
PIRiS03677.
RefSeqiNP_035883.2. NM_011753.3.
UniGeneiMm.107441.

3D structure databases

ProteinModelPortaliP10076.
SMRiP10076.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000124075.

PTM databases

iPTMnetiP10076.
PhosphoSitePlusiP10076.

Proteomic databases

MaxQBiP10076.
PaxDbiP10076.
PRIDEiP10076.

Protocols and materials databases

DNASUi22688.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22688.
KEGGimmu:22688.
UCSCiuc009oil.2. mouse.

Organism-specific databases

CTDi22688.
MGIiMGI:99173. Zfp26.
RougeiSearch...

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiP10076.
KOiK09228.
PhylomeDBiP10076.

Miscellaneous databases

PROiP10076.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000063108.
CleanExiMM_ZFP26.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 22 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 9 hits.
PF13912. zf-C2H2_6. 4 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 23 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 22 hits.
PS50157. ZINC_FINGER_C2H2_2. 23 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZFP26_MOUSE
AccessioniPrimary (citable) accession number: P10076
Secondary accession number(s): Q3UR72, Q5DTI1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: January 9, 2007
Last modified: November 2, 2016
This is version 141 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.