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Protein

Zinc finger protein 26

Gene

Zfp26

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri191 – 213C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri246 – 268C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 296C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri302 – 324C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri498 – 520C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri526 – 548C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 576C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri582 – 604C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri610 – 632C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri638 – 660C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri666 – 688C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri694 – 716C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri722 – 744C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri750 – 772C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri778 – 800C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri806 – 828C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri834 – 856C2H2-type 23; degeneratePROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 26
Short name:
Zfp-26
Alternative name(s):
Protein mKR3
Gene namesi
Name:Zfp26
Synonyms:Kiaa4196, Mkr3, Zfp-26
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:99173 Zfp26

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000472871 – 861Zinc finger protein 26Add BLAST861

Proteomic databases

MaxQBiP10076
PaxDbiP10076
PRIDEiP10076

PTM databases

iPTMnetiP10076
PhosphoSitePlusiP10076

Expressioni

Gene expression databases

CleanExiMM_ZFP26

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000124075

Structurei

3D structure databases

ProteinModelPortaliP10076
SMRiP10076
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 80KRABPROSITE-ProRule annotationAdd BLAST72

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri191 – 213C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri246 – 268C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 296C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri302 – 324C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri498 – 520C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri526 – 548C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 576C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri582 – 604C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri610 – 632C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri638 – 660C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri666 – 688C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri694 – 716C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri722 – 744C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri750 – 772C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri778 – 800C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri806 – 828C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri834 – 856C2H2-type 23; degeneratePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiP10076
KOiK09228
PhylomeDBiP10076

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 23 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 13 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 22 hits
PS50157 ZINC_FINGER_C2H2_2, 23 hits

Sequencei

Sequence statusi: Complete.

P10076-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METQQVDAVT FEDVAVDFTQ EEWTSLDPVQ RNLYRDVMLE NYQNLATVGG
60 70 80 90 100
QMFKPSLISW LEKKVELTVI EQGILQEWEM HLKTKRTALQ QDRFWSDMSN
110 120 130 140 150
GMQLGREHSG GEPGDPVQVG AVFSEDSCPQ THSSTSNTGN TFACNLDGKD
160 170 180 190 200
FQPLLKETST EENIVQLNQC VKPLIFTPDV SQKKCTPEKS VECSDCGETF
210 220 230 240 250
VNQLELQTHS SSHREKNIHK SEECGQASTH PISHGGHVIP TEKKYYECKK
260 270 280 290 300
CEKFFTHPVY LNIHMQSHTV EKPYDCKECG KAFTERSSLI VHLRQHTREK
310 320 330 340 350
SYECKECGKT FIQPSRLTEH MRSHTGEKPY QCDQCGNAFA SSSYLTTHLR
360 370 380 390 400
THTGEKPFEC NICGKAFTRS SYLLGHIRTH TGEKPYECKV CGKAFSGRSW
410 420 430 440 450
LTIHLRKHTG ERPYPCTECE KAFTSFAQLT EHIKTHTGEK PFRCKVCART
460 470 480 490 500
FRNSSCLKTH FRIHTGIKPY KCNYCGKAFT ARSGLTKHVL IHNGEKPYEC
510 520 530 540 550
KECGKAFSTS SGLVEHIRIH TGEKPFECYQ CGKALAHSSS LVGHLRTHTG
560 570 580 590 600
EKPFECNQCD KTFTRSSYLR IHMRTHTGEK PYECKECGKT FPERSCLTKH
610 620 630 640 650
IRTHTGERPY ECKECGKGFI SFAQLTVHIK THSSERPFQC KVCTKSFRNS
660 670 680 690 700
SSLETHFRIH TGVKPYKCSY CGKAFTARSG LTIHLRNHTG EKSYACQECG
710 720 730 740 750
KAFSTSSGLI AHIRSHKGEK PFECDHCGKA FASSSYLNVH LKIHTGEKPF
760 770 780 790 800
QCTVCGKTFT CSSYLPVHMR THTGEKPFQC IICGKSFLWS SYLRVHMRIH
810 820 830 840 850
TGEKPYVCQY CGKAFTEHSG LNKHLRKHTG EKPYEYKECG ENFTTSADAN
860
EHETPHWGEN L
Length:861
Mass (Da):97,989
Last modified:January 9, 2007 - v2
Checksum:i24E87864BCCD83A1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti460H → N in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti460H → N in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti476G → W in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti476G → W in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti536A → V in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti536A → V in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti616G → D in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti616G → D in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti681L → P in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti681L → P in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti732A → P in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti732A → P in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti751Q → R in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti751Q → R in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti775 – 776EK → GR in CAA31105 (PubMed:3143103).Curated2
Sequence conflicti775 – 776EK → GR in AAA37118 (PubMed:3143103).Curated2
Sequence conflicti779Q → R in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti779Q → R in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti785K → R in CAA31105 (PubMed:3143103).Curated1
Sequence conflicti785K → R in AAA37118 (PubMed:3143103).Curated1
Sequence conflicti859 – 860EN → DL in CAA31105 (PubMed:3143103).Curated2
Sequence conflicti859 – 860EN → DL in AAA37118 (PubMed:3143103).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK141740 mRNA Translation: BAE24816.1
AK220539 mRNA Translation: BAD90314.1
M36514 mRNA Translation: AAA37118.1
X12592 mRNA Translation: CAA31105.1
PIRiS03677
RefSeqiNP_035883.2, NM_011753.3
UniGeneiMm.107441

Genome annotation databases

GeneIDi22688
KEGGimmu:22688
UCSCiuc009oil.2 mouse

Similar proteinsi

Entry informationi

Entry nameiZFP26_MOUSE
AccessioniPrimary (citable) accession number: P10076
Secondary accession number(s): Q3UR72, Q5DTI1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: January 9, 2007
Last modified: February 28, 2018
This is version 149 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome