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Protein

Male determiner protein Yob

Gene

Yob

Organism
Anopheles gambiae (African malaria mosquito)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Male determiner protein (M-factor) that controls male somatic sexual differentiation. Acts as a dominant factor that regulates the mRNA splicing of doublesex (dsx) transcripts and promotes expression of male splice forms of dsx.1 Publication

GO - Biological processi

  • cell differentiation Source: UniProtKB-KW
  • male sex determination Source: UniProtKB
  • male sex differentiation Source: UniProtKB
  • mRNA processing Source: UniProtKB-KW
  • regulation of mRNA splicing, via spliceosome Source: UniProtKB
  • RNA splicing Source: UniProtKB-KW

Keywordsi

Biological processDifferentiation, mRNA processing, mRNA splicing, Sexual differentiation

Names & Taxonomyi

Protein namesi
Recommended name:
Male determiner protein Yob1 Publication
Gene namesi
Name:Yob1 Publication
OrganismiAnopheles gambiae (African malaria mosquito)
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Unassembled WGS sequence

Pathology & Biotechi

Disruption phenotypei

Male-specific lethality in embryos.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004413181 – 56Male determiner protein YobAdd BLAST56

Expressioni

Developmental stagei

Expression is male-specific. Transcription begins in embryos between 2 and 2.5 hours after oviposition, before blastoderm formation, and expression and continues throughout the life of the mosquito. Expression precedes establishment of sex-specific splicing of dsx by up to 6 hours.1 Publication

Structurei

3D structure databases

SMRiP0DP77.
ModBaseiSearch...
MobiDBiSearch...

Sequencei

Sequence statusi: Complete.

P0DP77-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSQSACVQV HIKTNELHTA VVEKVILAMI SSCRTDNNQA LHKLLHVAVC

EENYNV
Length:56
Mass (Da):6,281
Last modified:August 30, 2017 - v1
Checksum:i8FFA1CF177C01098
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008227 Genomic DNA. No translation available.

Entry informationi

Entry nameiYOB_ANOGA
AccessioniPrimary (citable) accession number: P0DP77
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2017
Last sequence update: August 30, 2017
Last modified: November 22, 2017
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome