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Protein

Omega-amidase YafV

Gene

yafV

Organism
Yersinia enterocolitica
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes alpha-ketoglutaramate (a-KGM) to alpha-ketoglutarate (alpha-KG) and ammonia (specific activity 21 µmol/min/mg), has very weak activity on L-glutamine, and no activity on deaminated glutathione (dGSH) or glutathione. May function as a metabolite repair enzyme.1 Publication

Catalytic activityi

A monoamide of a dicarboxylate + H2O = a dicarboxylate + NH3.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei42Proton acceptorPROSITE-ProRule annotation1
Active sitei107PROSITE-ProRule annotation1
Active sitei141NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Omega-amidase YafV (EC:3.5.1.31 Publication)
Short name:
yeYafV1 Publication
Gene namesi
Name:yafV1 Publication
ORF Names:CH48_2603
OrganismiYersinia enterocolitica
Taxonomic identifieri630 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004406981 – 256Omega-amidase YafVAdd BLAST256

Structurei

3D structure databases

SMRiP0DP67.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 234CN hydrolasePROSITE-ProRule annotationAdd BLAST231

Sequence similaritiesi

Family and domain databases

Gene3Di3.60.110.10. 1 hit.
InterProiView protein in InterPro
IPR003010. C-N_Hydrolase.
IPR036526. C-N_Hydrolase_sf.
IPR001110. UPF0012_CS.
PfamiView protein in Pfam
PF00795. CN_hydrolase. 1 hit.
SUPFAMiSSF56317. SSF56317. 1 hit.
PROSITEiView protein in PROSITE
PS50263. CN_HYDROLASE. 1 hit.
PS01227. UPF0012. 1 hit.

Sequencei

Sequence statusi: Complete.

P0DP67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLKLTLLQ QPLVWLDAQA NLRHFDMLLE SIQQRDVIVL PEMFTTGFAM
60 70 80 90 100
NAAENALPET EVIDWLRHWS VRTDALIGGS VALNTPDGAV NRFLLVQPDG
110 120 130 140 150
TILRYDKRHL FRMAGEHHHY LAGKERKVVE WRGWRILPQV CYDLRFPVWS
160 170 180 190 200
RNQQDYDLAL YVANWPAARA KHWQTLLAAR AIENQAYVAG CNRVGDDDNG
210 220 230 240 250
HHYQGNSVIL DALGEIQAQA EPGQAAQLDA ELSLETLQAY RERFPAFHDT

DKFLLL
Length:256
Mass (Da):29,269
Last modified:July 5, 2017 - v1
Checksum:i06614ECA1DF93F56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009838 Genomic DNA. Translation: AJJ26717.1.
RefSeqiWP_005164983.1. NZ_KN150739.1.

Similar proteinsi

Entry informationi

Entry nameiYAFV_YEREN
AccessioniPrimary (citable) accession number: P0DP67
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2017
Last sequence update: July 5, 2017
Last modified: March 28, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program