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Protein

Conantokin-Ca2

Gene
N/A
Organism
Conus caracteristicus (Characteristic cone)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors.By similarity

Miscellaneous

The mature peptide does not contain cysteine residue.Curated

GO - Molecular functioni

Keywordsi

Molecular functionIon channel impairing toxin, Ionotropic glutamate receptor inhibitor, Neurotoxin, Postsynaptic neurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conantokin-Ca21 Publication
Short name:
Con-Ca21 Publication
OrganismiConus caracteristicus (Characteristic cone)
Taxonomic identifieri89440 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeConus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00004393721 – 17Conantokin-Ca2Add BLAST17

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei34-carboxyglutamate1 Publication1
Modified residuei44-carboxyglutamate1 Publication1
Modified residuei64-carboxyglutamate1 Publication1
Modified residuei94-carboxyglutamate1 Publication1
Modified residuei134-carboxyglutamate1 Publication1

Keywords - PTMi

Gamma-carboxyglutamic acid

Expressioni

Tissue specificityi

Expressed by the venom duct.Curated

Sequencei

Sequence statusi: Complete.

P0DOZ5-1 [UniParc]FASTAAdd to basket

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        10 
GYEEREIAET VRELEEA
Length:17
Mass (Da):2,023
Last modified:April 12, 2017 - v1
Checksum:iB4B6146F7DCB568E
GO

Similar proteinsi

Entry informationi

Entry nameiCKC_CONCB
AccessioniPrimary (citable) accession number: P0DOZ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2017
Last sequence update: April 12, 2017
Last modified: November 22, 2017
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program