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Protein

Protein E8^E2C

Gene
N/A
Organism
Human papillomavirus type 5
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays a role in limiting the replication of viral DNA in keratinocytes. Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein E8^E2C
OrganismiHuman papillomavirus type 5
Taxonomic identifieri333923 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePapillomaviridaeBetapapillomavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000009252 Componenti: Genome

Subcellular locationi

  • Host nucleus By similarity

GO - Cellular componenti

Keywords - Cellular componenti

Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004387581 – 323Protein E8^E2CAdd BLAST323

Structurei

3D structure databases

SMRiP0DOD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR035975. E2/EBNA1_C_sf.
IPR000427. Papillomavirus_E2_C.
PfamiView protein in Pfam
PF00511. PPV_E2_C. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000672. E2_early_recog_prot_C. 1 hit.
SUPFAMiSSF54957. SSF54957. 1 hit.

Sequencei

Sequence statusi: Complete.

P0DOD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLKMLLLSS TPPGSPGGQA DTNTTPATPT TSTTAVDSTS RQLTTSKQPQ
60 70 80 90 100
QTETRGRRYG RRPSSKSRRS QTQQRRSRSR HRSRSRSRSR SKSQTHTTRS
110 120 130 140 150
TTRSRSTSLT KTRALTSRSR SRGRSPTTCR RGGGRSPRRR SRSPSTSSSC
160 170 180 190 200
TTQRSQRARA ESSTTRGARG SRGSRGGSRG GRGRRRGRSS SSSSPAHKRS
210 220 230 240 250
RGGSAKLRGV SPGEVGGSLR SVSSKHTGRL GRLLEEARDP PVIIVKGAAN
260 270 280 290 300
TLKCFRNRAK IKYMGLFRSF STTWSWVAGD GTERLGRPRM LISFSSYTQR
310 320
RDFDEAVRYP KGVDKAYGNL DSL
Length:323
Mass (Da):35,515
Last modified:January 18, 2017 - v1
Checksum:iE2239DB368EEDA92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M17463 Genomic DNA. No translation available.

Similar proteinsi

Entry informationi

Entry nameiVE8E2_HPV05
AccessioniPrimary (citable) accession number: P0DOD3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 18, 2017
Last sequence update: January 18, 2017
Last modified: November 22, 2017
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families