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Protein

Halorhodopsin

Gene

hop

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Light-driven chloride pump.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionPhotoreceptor protein, Receptor, Retinal protein
Biological processIon transport, Transport
LigandChloride, Chromophore

Names & Taxonomyi

Protein namesi
Recommended name:
Halorhodopsin
Short name:
HR
Gene namesi
Name:hop
Ordered Locus Names:VNG_0180G
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini22 – 25ExtracellularBy similarity4
Transmembranei26 – 51Helical; Name=Helix ABy similarityAdd BLAST26
Topological domaini52 – 57CytoplasmicBy similarity6
Transmembranei58 – 81Helical; Name=Helix BBy similarityAdd BLAST24
Topological domaini82 – 105ExtracellularBy similarityAdd BLAST24
Transmembranei106 – 127Helical; Name=Helix CBy similarityAdd BLAST22
Topological domaini128 – 130CytoplasmicBy similarity3
Transmembranei131 – 154Helical; Name=Helix DBy similarityAdd BLAST24
Topological domaini155 – 157ExtracellularBy similarity3
Transmembranei158 – 180Helical; Name=Helix EBy similarityAdd BLAST23
Topological domaini181 – 192CytoplasmicBy similarityAdd BLAST12
Transmembranei193 – 216Helical; Name=Helix FBy similarityAdd BLAST24
Topological domaini217 – 226ExtracellularBy similarity10
Transmembranei227 – 255Helical; Name=Helix GBy similarityAdd BLAST29
Topological domaini256 – 274CytoplasmicBy similarityAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PropeptideiPRO_00000202381 – 21By similarityAdd BLAST21
ChainiPRO_000002023922 – 274HalorhodopsinAdd BLAST253

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei242N6-(retinylidene)lysineBy similarity1

Proteomic databases

PaxDbiP0DMH7.

Interactioni

Subunit structurei

Homotrimer.By similarity

Protein-protein interaction databases

STRINGi64091.VNG0180G.

Structurei

3D structure databases

ProteinModelPortaliP0DMH7.
SMRiP0DMH7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG02811. Archaea.
COG5524. LUCA.
KOiK04642.
OMAiGRYLTWT.
OrthoDBiPOG093Z08PM.
PhylomeDBiP0DMH7.

Family and domain databases

InterProiView protein in InterPro
IPR001425. Arc/bac/fun_rhodopsins.
IPR018229. Rhodopsin_retinal_BS.
PANTHERiPTHR28286. PTHR28286. 1 hit.
PfamiView protein in Pfam
PF01036. Bac_rhodopsin. 1 hit.
PRINTSiPR00251. BACTRLOPSIN.
SMARTiView protein in SMART
SM01021. Bac_rhodopsin. 1 hit.
PROSITEiView protein in PROSITE
PS00950. BACTERIAL_OPSIN_1. 1 hit.
PS00327. BACTERIAL_OPSIN_RET. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0DMH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSITSVPGVV DAGVLGAQSA AAVRENALLS SSLWVNVALA GIAILVFVYM
60 70 80 90 100
GRTIRPGRPR LIWGATLMIP LVSISSYLGL LSGLTVGMIE MPAGHALAGE
110 120 130 140 150
MVRSQWGRYL TWALSTPMIL LALGLLADVD LGSLFTVIAA DIGMCVTGLA
160 170 180 190 200
AAMTTSALLF RWAFYAISCA FFVVVLSALV TDWAASASSA GTAEIFDTLR
210 220 230 240 250
VLTVVLWLGY PIVWAVGVEG LALVQSVGVT SWAYSVLDVF AKYVFAFILL
260 270
RWVANNERTV AVAGQTLGTM SSDD
Length:274
Mass (Da):28,874
Last modified:May 14, 2014 - v1
Checksum:i8FEDBBEDC717CD6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004437 Genomic DNA. Translation: AAG18795.1.
PIRiG84178.
RefSeqiWP_010902090.1. NC_002607.1.

Genome annotation databases

EnsemblBacteriaiAAG18795; AAG18795; VNG_0180G.
GeneIDi5952411.
KEGGihal:VNG_0180G.
PATRICifig|64091.14.peg.132.

Similar proteinsi

Entry informationi

Entry nameiBACH_HALSA
AccessioniPrimary (citable) accession number: P0DMH7
Secondary accession number(s): P16102, Q9HSK9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 14, 2014
Last sequence update: May 14, 2014
Last modified: June 7, 2017
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families