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P0DJW7

- PAX_I77AB

UniProt

P0DJW7 - PAX_I77AB

Protein

Protein PA-X

Gene

PA

Organism
Influenza A virus (strain A/USSR/90/1977 H1N1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
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    • History
      Entry version 7 (01 Oct 2014)
      Sequence version 1 (03 Oct 2012)
      Previous versions | rss
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    Functioni

    May play a role in the modulation of host immune response.By similarity

    GO - Molecular functioni

    1. RNA binding Source: InterPro
    2. RNA-directed RNA polymerase activity Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein PA-X
    Gene namesi
    Name:PA
    OrganismiInfluenza A virus (strain A/USSR/90/1977 H1N1)
    Taxonomic identifieri381516 [NCBI]
    Taxonomic lineageiVirusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A
    Virus hostiAves [TaxID: 8782]
    Homo sapiens (Human) [TaxID: 9606]
    Sus scrofa (Pig) [TaxID: 9823]
    ProteomesiUP000007793: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 252252Protein PA-XPRO_0000419430Add
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the influenza viruses PA-X family.Curated

    Family and domain databases

    InterProiIPR001009. RNA-dir_pol_influenzavirus.
    [Graphical view]
    PfamiPF00603. Flu_PA. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by ribosomal frameshifting. Align

    Isoform PA-X (identifier: P0DJW7-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEDFVRQCFN PMIVELAEKA MKEYGEDLKI ETNKFAAICT HLEVCFMYSD    50
    FHFINEQGES IIVELDDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGA 100
    EKPKFLPDLY DYKENRFIEI GVTRREVHIY YLEKANKIKS EKTHIHIFSF 150
    TGEEMATKAD YTLDEESRAR IKTRLFTIRQ EMASRGLWDS FVSPREAKKQ 200
    LKKDLKSQEQ CAGSPTKVSR RTSPALRILE PMWMDSNRTA TLRASFLKCP 250
    KK 252
    Length:252
    Mass (Da):29,439
    Last modified:October 3, 2012 - v1
    Checksum:i2E005AA1253BBE50
    GO
    Isoform PA (identifier: Q1WP02-1) [UniParc]FASTAAdd to Basket

    The sequence of this isoform can be found in the external entry Q1WP02.
    Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
    Length:716
    Mass (Da):82,834
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CY010377 Genomic RNA. No translation available.
    DQ508896 Genomic RNA. No translation available.

    Keywords - Coding sequence diversityi

    Ribosomal frameshifting

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CY010377 Genomic RNA. No translation available.
    DQ508896 Genomic RNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR001009. RNA-dir_pol_influenzavirus.
    [Graphical view ]
    Pfami PF00603. Flu_PA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    2. "Complete genome sequencing and analysis of selected influenza virus vaccine strains spanning six decades (1933-1999)."
      Mbawuike I.N., Zhang Y., Yamada R.E., Nino D., Bui H.-H., Sette A., Couch R.B.
      Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiPAX_I77AB
    AccessioniPrimary (citable) accession number: P0DJW7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 3, 2012
    Last sequence update: October 3, 2012
    Last modified: October 1, 2014
    This is version 7 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3