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P0DJW2

- PAX_I45A0

UniProt

P0DJW2 - PAX_I45A0

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Protein

Protein PA-X

Gene

PA

Organism
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

May play a role in the modulation of host immune response.By similarity

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. RNA-directed RNA polymerase activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PA-X
Gene namesi
Name:PA
OrganismiInfluenza A virus (strain A/USA:Huston/AA/1945 H1N1)
Taxonomic identifieri425551 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A
Virus hostiAves [TaxID: 8782]
Homo sapiens (Human) [TaxID: 9606]
Sus scrofa (Pig) [TaxID: 9823]
ProteomesiUP000008433: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 252252Protein PA-XPRO_0000419425Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the influenza viruses PA-X family.Curated

Family and domain databases

InterProiIPR001009. RNA-dir_pol_influenzavirus.
[Graphical view]
PfamiPF00603. Flu_PA. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by ribosomal frameshifting. Align

Isoform PA-X (identifier: P0DJW2-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEDFVRQCFN PMIVELAEKA MKEYGEDLKV ETNKFAAICT HLEVCFMYSD
60 70 80 90 100
FHFINEQGES IIVELGDPNA LLKHRFEIIE GRDRTMAWTI VNSICNTTGA
110 120 130 140 150
EKPKFLPDLY DYKENRFIEI GVTRREVHIY YLEKANKIKS EKTHIHIFSF
160 170 180 190 200
TGEEMATKAD YTLDEESRAR IKTRLFTIRQ EMASRGLWDS FVSPREAKRQ
210 220 230 240 250
LKKDLKSQEQ CASSPTKVSR RTSPALKILE PMWMDSNRTA TLRASFLKCP

KK
Length:252
Mass (Da):29,411
Last modified:October 3, 2012 - v1
Checksum:i67DF9DDA1C6AECD5
GO
Isoform PA (identifier: A4U6V9-1) [UniParc]FASTAAdd to Basket

The sequence of this isoform can be found in the external entry A4U6V9.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:716
Mass (Da):82,663
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CY021714 Viral cRNA. No translation available.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CY021714 Viral cRNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR001009. RNA-dir_pol_influenzavirus.
[Graphical view ]
Pfami PF00603. Flu_PA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. The NIAID Influenza Genome Sequencing Consortium
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiPAX_I45A0
AccessioniPrimary (citable) accession number: P0DJW2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: October 3, 2012
Last modified: October 1, 2014
This is version 7 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3