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Protein

Protein PA-X

Gene

PA

Organism
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May play a role in the modulation of host immune response.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PA-X
Gene namesi
Name:PA
OrganismiInfluenza A virus (strain A/USA:Huston/AA/1945 H1N1)
Taxonomic identifieri425551 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A
Virus hostiAves [TaxID: 8782]
Homo sapiens (Human) [TaxID: 9606]
Sus scrofa (Pig) [TaxID: 9823]
Proteomesi
  • UP000173607 Componenti: Segment 3
  • UP000008433 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004194251 – 252Protein PA-XAdd BLAST252

Family & Domainsi

Sequence similaritiesi

Belongs to the influenza viruses PA-X family.Curated

Phylogenomic databases

OrthoDBiVOG090E000C.

Family and domain databases

InterProiView protein in InterPro
IPR001009. RNA-dir_pol_influenzavirus.
PfamiView protein in Pfam
PF00603. Flu_PA. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Isoform PA-X (identifier: P0DJW2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEDFVRQCFN PMIVELAEKA MKEYGEDLKV ETNKFAAICT HLEVCFMYSD
60 70 80 90 100
FHFINEQGES IIVELGDPNA LLKHRFEIIE GRDRTMAWTI VNSICNTTGA
110 120 130 140 150
EKPKFLPDLY DYKENRFIEI GVTRREVHIY YLEKANKIKS EKTHIHIFSF
160 170 180 190 200
TGEEMATKAD YTLDEESRAR IKTRLFTIRQ EMASRGLWDS FVSPREAKRQ
210 220 230 240 250
LKKDLKSQEQ CASSPTKVSR RTSPALKILE PMWMDSNRTA TLRASFLKCP

KK
Length:252
Mass (Da):29,411
Last modified:October 3, 2012 - v1
Checksum:i67DF9DDA1C6AECD5
GO
Isoform PA (identifier: A4U6V9-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry A4U6V9.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:716
Mass (Da):82,663
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CY021714 Viral cRNA. No translation available.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CY021714 Viral cRNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

OrthoDBiVOG090E000C.

Family and domain databases

InterProiView protein in InterPro
IPR001009. RNA-dir_pol_influenzavirus.
PfamiView protein in Pfam
PF00603. Flu_PA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPAX_I45A0
AccessioniPrimary (citable) accession number: P0DJW2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: October 3, 2012
Last modified: February 15, 2017
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.