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P0DJV1

- PAX_I77AD

UniProt

P0DJV1 - PAX_I77AD

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Protein

Protein PA-X

Gene

PA

Organism
Influenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

May play a role in the modulation of host immune response.By similarity

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. RNA-directed RNA polymerase activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PA-X
Gene namesi
Name:PA
OrganismiInfluenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)
Taxonomic identifieri384479 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A
Virus hostiAves [TaxID: 8782]
Homo sapiens (Human) [TaxID: 9606]
Sus scrofa (Pig) [TaxID: 9823]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 252252Protein PA-XPRO_0000419414Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the influenza viruses PA-X family.Curated

Family and domain databases

InterProiIPR001009. RNA-dir_pol_influenzavirus.
[Graphical view]
PfamiPF00603. Flu_PA. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by ribosomal frameshifting. Align

Isoform PA-X (identifier: P0DJV1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEDFVRQCFN PMIVELAEKT MKEYGENPKI ETNKFAAICT HMEVCFMYSD
60 70 80 90 100
FHFINERGES IIIEPGDSNA LLKHRFEIIE GRDRNMAWTV VNSICNTTGV
110 120 130 140 150
GKPRFLPDLY DYKEDRFIKI GVTRREVHIY YLEKANKIKS EETHIHIFSF
160 170 180 190 200
TGEEMATKAD YTLDEESRAR IKTRLFTIRQ EMASRGLWDS FVSPREAKRQ
210 220 230 240 250
LKKDLKSKGQ CEGLLTKVSH QTSQVSTTLE PMWMDSSRMA TLRASFPKCL

EK
Length:252
Mass (Da):29,405
Last modified:October 3, 2012 - v1
Checksum:iB0EC3E9F4BB22BF7
GO
Isoform PA (identifier: P13177-1) [UniParc]FASTAAdd to Basket

The sequence of this isoform can be found in the external entry P13177.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:716
Mass (Da):82,873
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M26077 Genomic RNA. No translation available.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M26077 Genomic RNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR001009. RNA-dir_pol_influenzavirus.
[Graphical view ]
Pfami PF00603. Flu_PA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolutionary pathways of the PA genes of influenza A viruses."
    Okazaki K., Kawaoka Y., Webster R.G.
    Virology 172:601-608(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiPAX_I77AD
AccessioniPrimary (citable) accession number: P0DJV1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: October 3, 2012
Last modified: October 1, 2014
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3