P0DJR5 (PAX_I36A0) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein PA-X

Gene names

Name:

PA

Organism

Influenza A virus (strain A/Henry/1936 H1N1) [Complete proteome]

Taxonomic identifier

425562 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Orthomyxoviridae › Influenzavirus A › Influenza A virus › H1N1 subtype

Virus host

Aves [TaxID: 8782]
Homo sapiens (Human) [TaxID: 9606]
Sus scrofa (Pig) [TaxID: 9823]

Protein attributes

Sequence length	252 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in the modulation of host immune response By similarity.
Sequence similarities	Belongs to the influenza viruses PA-X family.

Ontologies

Keywords
Coding sequence diversity	Ribosomal frameshifting
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro RNA-directed RNA polymerase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by ribosomal frameshifting. [Align] [Select]

Isoform PA-X (identifier: P0DJR5-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform PA (identifier: A4GCJ3-1)

The sequence of this isoform can be found in the external entry A4GCJ3.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 252	252	Protein PA-X		PRO_0000419378

Sequences

	Sequence		Length	Mass (Da)
	Isoform PA-X [UniParc]. Last modified October 3, 2012. Version 1. Checksum: 7B63421BBA38F71A	FASTA	252	29,484
	10 20 30 40 50 60 MEDFVRQCFN PMIVELAEKT MKEYGENLKI ETNKFAAICT HLEVCFMYSD FHFINEQGES 70 80 90 100 110 120 TIVELGDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGA EKPKFLPDLY DYKENRFIEI 130 140 150 160 170 180 GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKTD YTLDEESRAR IKTRLFTIRQ 190 200 210 220 230 240 EMASRGLWDS FVSPREEKRQ LKKGLKSQEQ CASLPTKVSR RTSPALKILE PMWMDSNRTA 250 TLRASFLKCP KK
	Isoform PA [UniParc]. See A4GCJ3.		–	–

References

[1]

"The NIAID influenza genome sequencing project." Ghedin E., Spiro D., Miller N., Zaborsky J., Feldblyum T., Subbu V., Shumway M., Sparenborg J., Groveman L., Halpin R., Sitz J., Koo H., Salzberg S.L., Webster R.G., Hoffmann E., Krauss S., Naeve C., Bao Y. , Bolotov P., Dernovoy D., Kiryutin B., Lipman D.J., Tatusova T. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

[2]

The NIAID Influenza Genome Sequencing Consortium Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CY020450 Viral cRNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001009. RNA-dir_pol_influenzavirus. [Graphical view]
Pfam	PF00603. Flu_PA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PAX_I36A0

Accession

Primary (citable) accession number: P0DJR5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 3, 2012
Last sequence update:	October 3, 2012
Last modified:	November 28, 2012
This is version 3 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program