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Protein

Small integral membrane protein 13

Gene

SMIM13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Small integral membrane protein 13
Gene namesi
Name:SMIM13
Synonyms:C6orf228
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:27356. SMIM13.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei10 – 3021HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9191Small integral membrane protein 13PRO_0000414060Add
BLAST

Proteomic databases

MaxQBiP0DJ93.
PRIDEiP0DJ93.

PTM databases

PhosphoSiteiP0DJ93.

Expressioni

Gene expression databases

BgeeiP0DJ93.

Organism-specific databases

HPAiHPA065706.

Structurei

3D structure databases

ProteinModelPortaliP0DJ93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SMIM13 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00560000078630.
InParanoidiP0DJ93.
OMAiWHLFLSK.
OrthoDBiEOG7CRTTB.

Sequencei

Sequence statusi: Complete.

P0DJ93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWHSVGLTLL VFVATLLIVL LLMVCGWYFV WHLFLSKFKF LRELVGDTGS
60 70 80 90
QEGDHEPSGS ETEEDTSSSP HRIRSARQRR APADEGHRPL T
Length:91
Mass (Da):10,351
Last modified:December 14, 2011 - v1
Checksum:i9394704F780C22A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136139 Genomic DNA. No translation available.
BC032356 mRNA. No translation available.
CCDSiCCDS56396.1.
RefSeqiNP_001129047.1. NM_001135575.1.
UniGeneiHs.656600.

Genome annotation databases

EnsembliENST00000376935; ENSP00000452219; ENSG00000224531.
ENST00000416247; ENSP00000451866; ENSG00000224531.
GeneIDi221710.
KEGGihsa:221710.
UCSCiuc011dio.2. human.

Polymorphism databases

DMDMi363579843.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136139 Genomic DNA. No translation available.
BC032356 mRNA. No translation available.
CCDSiCCDS56396.1.
RefSeqiNP_001129047.1. NM_001135575.1.
UniGeneiHs.656600.

3D structure databases

ProteinModelPortaliP0DJ93.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiP0DJ93.

Polymorphism databases

DMDMi363579843.

Proteomic databases

MaxQBiP0DJ93.
PRIDEiP0DJ93.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000376935; ENSP00000452219; ENSG00000224531.
ENST00000416247; ENSP00000451866; ENSG00000224531.
GeneIDi221710.
KEGGihsa:221710.
UCSCiuc011dio.2. human.

Organism-specific databases

CTDi221710.
GeneCardsiGC06P011097.
HGNCiHGNC:27356. SMIM13.
HPAiHPA065706.
neXtProtiNX_P0DJ93.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00560000078630.
InParanoidiP0DJ93.
OMAiWHLFLSK.
OrthoDBiEOG7CRTTB.

Miscellaneous databases

GenomeRNAii221710.
NextBioi91421.

Gene expression databases

BgeeiP0DJ93.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Bone marrow.

Entry informationi

Entry nameiSIM13_HUMAN
AccessioniPrimary (citable) accession number: P0DJ93
Secondary accession number(s): G3V581
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: December 14, 2011
Last modified: March 4, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.