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P0DJ07 (PT100_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein PET100 homolog, mitochondrial
Gene names
Name:PET100
Synonyms:C19orf79
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length73 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with COX7A2. Ref.3

Subcellular location

Membrane; Single-pass membrane protein Potential. Mitochondrion By similarity. Note: Localizes to a membrane-bound organelle. Ref.3

Sequence similarities

Belongs to the PET100 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion
Chain? – 73Protein PET100 homolog, mitochondrialPRO_0000413099

Regions

Transmembrane7 – 2418Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P0DJ07 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: CE20E13A4155616C

FASTA739,114
        10         20         30         40         50         60 
MGVKLEIFRM IIYLTFPVAM FWVSNQAEWF EDDVIQRKRE LWPPEKLQEI EEFKERLRKR 

        70 
REEKLLRDAQ QNS 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence and biology of human chromosome 19."
Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V. expand/collapse author list , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]"Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase."
Szklarczyk R., Wanschers B.F., Cuypers T.D., Esseling J.J., Riemersma M., van den Brand M.A., Gloerich J., Lasonder E., van den Heuvel L.P., Nijtmans L.G., Huynen M.A.
Genome Biol. 13:RESEARCH0012.1-RESEARCH0012.14(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH COX7A2, SUBCELLULAR LOCATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC008763 Genomic DNA. No translation available.
BC150496 mRNA. No translation available.
CCDSCCDS54208.1.
RefSeqNP_001164626.1. NM_001171155.1.
UniGeneHs.728837.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid935494. 1 interaction.

Polymorphism databases

DMDM353558869.

Proteomic databases

MaxQBP0DJ07.
PRIDEP0DJ07.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000594797; ENSP00000470539; ENSG00000229833.
GeneID100131801.
KEGGhsa:100131801.
UCSCuc010dvi.2. human.

Organism-specific databases

CTD100131801.
GeneCardsGC19P007719.
HGNCHGNC:40038. PET100.
MIM614770. gene.
neXtProtNX_P0DJ07.
Orphanet254905. Isolated cytochrome C oxidase deficiency.
GenAtlasSearch...

Phylogenomic databases

KOK18186.
OMAAEWFEDY.
OrthoDBEOG7GBG0Q.
PhylomeDBP0DJ07.
TreeFamTF314727.

Gene expression databases

BgeeP0DJ07.

Family and domain databases

InterProIPR018625. DUF2346.
[Graphical view]
PfamPF09803. DUF2346. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSC19orf79. human.
NextBio20773576.
PROP0DJ07.
SOURCESearch...

Entry information

Entry namePT100_HUMAN
AccessionPrimary (citable) accession number: P0DJ07
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: October 19, 2011
Last modified: July 9, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 19

Human chromosome 19: entries, gene names and cross-references to MIM