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P0DJ07

- PT100_HUMAN

UniProt

P0DJ07 - PT100_HUMAN

Protein

Protein PET100 homolog, mitochondrial

Gene

PET100

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein PET100 homolog, mitochondrial
    Gene namesi
    Name:PET100
    Synonyms:C19orf79
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:40038. PET100.

    Subcellular locationi

    Membrane Curated; Single-pass membrane protein Curated. Mitochondrion By similarity
    Note: Localizes to a membrane-bound organelle.1 Publication

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion

    Pathology & Biotechi

    Organism-specific databases

    Orphaneti254905. Isolated cytochrome C oxidase deficiency.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini? – 73Protein PET100 homolog, mitochondrialPRO_0000413099
    Transit peptidei1 – ?Mitochondrion

    Proteomic databases

    MaxQBiP0DJ07.
    PRIDEiP0DJ07.

    Expressioni

    Gene expression databases

    BgeeiP0DJ07.

    Interactioni

    Subunit structurei

    Interacts with COX7A2.1 Publication

    Protein-protein interaction databases

    BioGridi935494. 1 interaction.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei7 – 2418HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PET100 family.Curated

    Keywords - Domaini

    Transit peptide, Transmembrane, Transmembrane helix

    Phylogenomic databases

    KOiK18186.
    OMAiAEWFEDY.
    OrthoDBiEOG7GBG0Q.
    PhylomeDBiP0DJ07.
    TreeFamiTF314727.

    Family and domain databases

    InterProiIPR018625. DUF2346.
    [Graphical view]
    PfamiPF09803. DUF2346. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P0DJ07-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGVKLEIFRM IIYLTFPVAM FWVSNQAEWF EDDVIQRKRE LWPPEKLQEI   50
    EEFKERLRKR REEKLLRDAQ QNS 73
    Length:73
    Mass (Da):9,114
    Last modified:October 19, 2011 - v1
    Checksum:iCE20E13A4155616C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008763 Genomic DNA. No translation available.
    BC150496 mRNA. No translation available.
    CCDSiCCDS54208.1.
    RefSeqiNP_001164626.1. NM_001171155.1.
    UniGeneiHs.728837.

    Genome annotation databases

    EnsembliENST00000594797; ENSP00000470539; ENSG00000229833.
    GeneIDi100131801.
    KEGGihsa:100131801.
    UCSCiuc010dvi.2. human.

    Polymorphism databases

    DMDMi353558869.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008763 Genomic DNA. No translation available.
    BC150496 mRNA. No translation available.
    CCDSi CCDS54208.1.
    RefSeqi NP_001164626.1. NM_001171155.1.
    UniGenei Hs.728837.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 935494. 1 interaction.

    Polymorphism databases

    DMDMi 353558869.

    Proteomic databases

    MaxQBi P0DJ07.
    PRIDEi P0DJ07.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000594797 ; ENSP00000470539 ; ENSG00000229833 .
    GeneIDi 100131801.
    KEGGi hsa:100131801.
    UCSCi uc010dvi.2. human.

    Organism-specific databases

    CTDi 100131801.
    GeneCardsi GC19P007719.
    HGNCi HGNC:40038. PET100.
    MIMi 614770. gene.
    neXtProti NX_P0DJ07.
    Orphaneti 254905. Isolated cytochrome C oxidase deficiency.
    GenAtlasi Search...

    Phylogenomic databases

    KOi K18186.
    OMAi AEWFEDY.
    OrthoDBi EOG7GBG0Q.
    PhylomeDBi P0DJ07.
    TreeFami TF314727.

    Miscellaneous databases

    ChiTaRSi C19orf79. human.
    NextBioi 20773576.
    PROi P0DJ07.
    SOURCEi Search...

    Gene expression databases

    Bgeei P0DJ07.

    Family and domain databases

    InterProi IPR018625. DUF2346.
    [Graphical view ]
    Pfami PF09803. DUF2346. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    3. "Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase."
      Szklarczyk R., Wanschers B.F., Cuypers T.D., Esseling J.J., Riemersma M., van den Brand M.A., Gloerich J., Lasonder E., van den Heuvel L.P., Nijtmans L.G., Huynen M.A.
      Genome Biol. 13:RESEARCH0012.1-RESEARCH0012.14(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH COX7A2, SUBCELLULAR LOCATION.

    Entry informationi

    Entry nameiPT100_HUMAN
    AccessioniPrimary (citable) accession number: P0DJ07
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3