Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ras-related protein Rab-34, isoform NARR

Gene

RAB34

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein Rab-34, isoform NARR
Alternative name(s):
Nine amino-acid residue-repeats
Gene namesi
Name:RAB34
Synonyms:NARR
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:16519. RAB34.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

DisGeNETi83871.
OpenTargetsiENSG00000109113.

Polymorphism and mutation databases

BioMutaiRAB34.
DMDMi347602360.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00004125332 – 198Ras-related protein Rab-34, isoform NARRAdd BLAST197

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei13Phosphoserine1 Publication1
Modified residuei69Phosphothreonine1 Publication1
Modified residuei78Phosphoserine1 Publication1
Modified residuei87Phosphoserine1 Publication1
Modified residuei96Phosphoserine1 Publication1
Modified residuei123Phosphoserine1 Publication1

Post-translational modificationi

Phosphorylated during M-phase.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiP0DI83.
PeptideAtlasiP0DI83.
PRIDEiP0DI83.

PTM databases

iPTMnetiP0DI83.
PhosphoSitePlusiP0DI83.
SwissPalmiP0DI83.

Expressioni

Gene expression databases

ExpressionAtlasiP0DI83. baseline and differential.

Interactioni

Subunit structurei

May interact with EIF5A and ERF1.

Protein-protein interaction databases

IntActiP0DI83. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliP0DI83.
SMRiP0DI83.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati7 – 1511 Publication9
Repeati16 – 2421 Publication9
Repeati25 – 3331 Publication9
Repeati34 – 4241 Publication9
Repeati43 – 5151 Publication9
Repeati52 – 6061 Publication9
Repeati61 – 6971 Publication9
Repeati70 – 7881 Publication9
Repeati79 – 8791 Publication9
Repeati88 – 96101 Publication9
Repeati97 – 105111 Publication9
Repeati106 – 114121 Publication9
Repeati115 – 123131 Publication9

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni7 – 12513 x 9 AA approximate tandem-repeats of P-R-V-I-V-G-(S/T)-P-RAdd BLAST119

Keywords - Domaini

Repeat

Phylogenomic databases

GeneTreeiENSGT00900000140929.

Sequences (3)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform NARR (identifier: P0DI83-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVGQPQPRDD VGSPRPRVIV GTIRPRVIVG TIRPRVIVGS ARARPPPDGT
60 70 80 90 100
PRPQLAAEES PRPRVIFGTP RARVILGSPR PRVIVSSPWP AVVVASPRPR
110 120 130 140 150
TPVGSPWPRV VVGTPRPRVI VGSPRARVAD ADPASAPSQG ALQGRRQDEH
160 170 180 190
SGTRAEGSRP GGAAPVPEEG GRFARAQRLP PPRHLRLPGA PDRHRGQI
Length:198
Mass (Da):21,118
Last modified:September 21, 2011 - v1
Checksum:iE03CF9EB3272B766
GO
Isoform 1 (identifier: Q9BZG1-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry Q9BZG1.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:259
Mass (Da):29,044
GO
Isoform 2 (identifier: Q9BZG1-2) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry Q9BZG1.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:251
Mass (Da):28,230
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010761 Genomic DNA. No translation available.
CX872465 mRNA. No translation available.
RefSeqiNP_001243210.1. NM_001256281.2. [P0DI83-1]
UniGeneiHs.301853.

Genome annotation databases

EnsembliENST00000636154; ENSP00000490450; ENSG00000109113. [P0DI83-1]
GeneIDi83871.

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiNARR_HUMAN
AccessioniPrimary (citable) accession number: P0DI83
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: September 21, 2011
Last modified: October 25, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Shares its exons with RAB34, but the first 5'-exon is longer and the translation ccurs 443 base pairs upstream from RAB34 initiator, in another frame. May be produced by an alternative promoter.Curated

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM