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Protein

UTP--glucose-1-phosphate uridylyltransferase 2

Gene

hasC2

Organism
Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathwayi: nucleotide-sugar metabolism

This protein is involved in the pathway nucleotide-sugar metabolism, which is part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the pathway nucleotide-sugar metabolism and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00215

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase 2 (EC:2.7.7.9)
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase 2
UDP-glucose pyrophosphorylase 2
Short name:
UDPGP 2
Uridine diphosphoglucose pyrophosphorylase 2
Gene namesi
Name:hasC2
Synonyms:hasC.2
Ordered Locus Names:SpyM3_0160
OrganismiStreptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Taxonomic identifieri198466 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000564 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002013731 – 299UTP--glucose-1-phosphate uridylyltransferase 2Add BLAST299

Structurei

3D structure databases

ProteinModelPortaliP0DG72
SMRiP0DG72
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 2 family.Curated

Phylogenomic databases

HOGENOMiHOG000283477
KOiK00963
OMAiYDCGKPE

Family and domain databases

CDDicd02541 UGPase_prokaryotic, 1 hit
Gene3Di3.90.550.101 hit
InterProiView protein in InterPro
IPR005771 GalU_uridylyltTrfase_bac/arc
IPR005835 NTP_transferase_dom
IPR029044 Nucleotide-diphossugar_trans
PANTHERiPTHR43197 PTHR43197, 1 hit
PfamiView protein in Pfam
PF00483 NTP_transferase, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit
TIGRFAMsiTIGR01099 galU, 1 hit

Sequencei

Sequence statusi: Complete.

P0DG72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKVRKAIIP AAGLGTRFLP ATKALAKEML PIVDKPTIQF IVEEALKSGI
60 70 80 90 100
EEILIVTGKS KRSIEDHFDS NFELEYNLQA KGKIELLKLV DETTSINLHF
110 120 130 140 150
IRQSHPRGLG DAVLQAKTFV GNEPFVVMLG DDLMDITNPN VKPLTKQLID
160 170 180 190 200
DYEETHAATI AVMRVPHEDV SNYGIIAPQA KAVKGLYSVD TFVEKPQPQD
210 220 230 240 250
APSDLAIIGR YLLTPEIFSI LEKQEPGAGN EVQLTDAIDT LNKTQRVFAR
260 270 280 290
EFKGKRYDVG DKFGFMKTSL DYALKHPQVK DDLKAYIIQL GKALEKTKP
Length:299
Mass (Da):33,302
Last modified:July 27, 2011 - v1
Checksum:iD927314E58F6091B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014074 Genomic DNA Translation: AAM78767.1
RefSeqiWP_002986125.1, NC_004070.1

Genome annotation databases

EnsemblBacteriaiAAM78767; AAM78767; SpyM3_0160
KEGGispg:SpyM3_0160

Similar proteinsi

Entry informationi

Entry nameiHASC2_STRP3
AccessioniPrimary (citable) accession number: P0DG72
Secondary accession number(s): P58098, P67069
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome