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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Streptococcus pyogenes serotype M3 (strain SSI-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei39NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:SPs1087
OrganismiStreptococcus pyogenes serotype M3 (strain SSI-1)
Taxonomic identifieri193567 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004114641 – 294tRNA pseudouridine synthase BAdd BLAST294

Structurei

3D structure databases

ProteinModelPortaliP0DD49
SMRiP0DD49
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

P0DD49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINGIINLKK EAGMTSHDAV FKLRKLLQEK KIGHGGTLDP DVVGVLPIAV
60 70 80 90 100
GKATRVIEYM TEAGKVYEGQ VTLGYSTTTE DASGEVVARS SLPAVLTEEL
110 120 130 140 150
VDQTMTTFLG KITQTPPMYS AVKVNGRKLY EYARAGESVE RPRREVTISL
160 170 180 190 200
FERTSPLNFT EDGLCRFSFK VACGKGTYVR TLAVDLGRAL GVESHMSFLQ
210 220 230 240 250
RSASAGLTLE TAYTLGEIAD MVSKQEMSFL LPIEYGVADL PKMVIDDTEL
260 270 280 290
TEISFGRRLS LPSQEPLLAA FHGEKVIAIL EKRDQEYKPK KVLI
Length:294
Mass (Da):32,315
Last modified:July 27, 2011 - v1
Checksum:i98E9A7E6AB9FC358
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000034 Genomic DNA Translation: BAC64182.1
RefSeqiWP_011054534.1, NC_004606.1

Genome annotation databases

EnsemblBacteriaiBAC64182; BAC64182; BAC64182
KEGGisps:SPs1087

Similar proteinsi

Entry informationi

Entry nameiTRUB_STRPQ
AccessioniPrimary (citable) accession number: P0DD49
Secondary accession number(s): Q878P4, Q8K7B8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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