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P0DC98

- CAPP_STRP3

UniProt

P0DC98 - CAPP_STRP3

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, SpyM3_0430
Organism
Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarity
Active sitei583 – 5831 By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciSPYO198466:GJDL-486-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase (EC:4.1.1.31)
Short name:
PEPC
Short name:
PEPCase
Gene namesi
Name:ppc
Ordered Locus Names:SpyM3_0430
OrganismiStreptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Taxonomic identifieri198466 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000564: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 920920Phosphoenolpyruvate carboxylaseUniRule annotation
PRO_0000166633Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP0DC98.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiELSTISC.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0DC98-1 [UniParc]FASTAAdd to Basket

« Hide

MPLKKLESSN NQTIIAEEVA LLKEMLENIT RRMIGDDAFT VIESIMVLSE    50
KQDYIELEKV VANISNQEME VISRYFSILP LLINISEDVD LAYEINHQNN 100
TDTDYLGKLA LTIKDLAGKD NGKDILEQVN VVPVLTAHPT QVQRKTILEL 150
TTHIHKLLRK YRDAKAGVIN LEKWRQELYR YIEMIMQTDI IREKKLQVKN 200
EIKNVMQYYD GSLIQAVTKL TTEYKNLAQK HGLELDNPKP ITMGMWIGGD 250
RDGNPFVTAE TLCLSATVQS EVILNYYIDK LAALYRTFSL SSTLVQPNSE 300
VERLASLSQD QSIYRGNEPY RRAFHYIQSR LKQTQIQLTN QPAARMSSSV 350
GLNTSAWSSP ASLENPILAY DSPVDFKADL KAIEQSLLDN GNSALIEGDL 400
REVMQAVDIF GFFLASIDMR QDSSVQEACV AELLKGANIV DDYSSLSETE 450
KCDVLLQQLM EEPRTLSSAA VAKSDLLEKE LAIYTTAREL KDKLGEEVIK 500
QHIISHTESV SDMFELAIML KEVGLVDQQR ARVQIVPLFE TIEDLDNARD 550
IMAAYLSHDI VKSWIATNRN YQEIMLGYSD SNKDGGYLAS GWTLYKAQNE 600
LTAIGEEHGV KITFFHGRGG TVGRGGGPSY DAITSQPFGS IKDRIRLTEQ 650
GEIIENKYGN KDVAYYHLEM LISASINRMV TQMITDPNEI DSFREIMDSI 700
VADSNTIYRK LVFDNPHFYD YFFEASPIKE VSSLNIGSRP AARKTITEIT 750
GLRAIPWVFS WSQNRIMFPG WYGVGSAFKR YIDRAQGNLE RLQHMYQTWP 800
FFHSLLSNVD MVLSKSNMNI AFQYAQLAES QDVRDVFYEI LDEWQLTKNV 850
ILAIQDHDDL LEDNPSLKHS LKSRLPYFNV LNYIQIELIK RWRNNQLDEN 900
DEKLIHTTIN GIATGLRNSG 920
Length:920
Mass (Da):104,699
Last modified:July 27, 2011 - v1
Checksum:iA7837E73861919F7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014074 Genomic DNA. Translation: AAM79037.1.
RefSeqiNP_664234.1. NC_004070.1.

Genome annotation databases

EnsemblBacteriaiAAM79037; AAM79037; SpyM3_0430.
GeneIDi1008744.
KEGGispg:SpyM3_0430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014074 Genomic DNA. Translation: AAM79037.1 .
RefSeqi NP_664234.1. NC_004070.1.

3D structure databases

ProteinModelPortali P0DC98.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM79037 ; AAM79037 ; SpyM3_0430 .
GeneIDi 1008744.
KEGGi spg:SpyM3_0430.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.
OMAi ELSTISC.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci SPYO198466:GJDL-486-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence."
    Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D., Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S., Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.
    Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-595 / MGAS315.

Entry informationi

Entry nameiCAPP_STRP3
AccessioniPrimary (citable) accession number: P0DC98
Secondary accession number(s): Q8K873
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: July 27, 2011
Last modified: May 14, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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