P0DB30Q8K7K9GCH1_STRP3GTP cyclohydrolase 13.5.4.16GTP cyclohydrolase IGTP-CH-IfolESpyM3_0759Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)BacteriaBacillotaBacilliLactobacillalesStreptococcaceaeStreptococcusGenome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.Toroid-shaped homodecamer, composed of two pentamers of five dimers.Belongs to the GTP cyclohydrolase I family.GTP-bindingHydrolaseMetal-bindingNucleotide-bindingOne-carbon metabolismZincZn(2+)Zn(2+)Zn(2+)MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKMYAEMFLGLGKDPKEEFTAVFKEHHEDVVIVKDISFYSVCEHHLVPFYGKAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRGIKKPGSKTITTTARGLYKESRAERQEVISLMTKD
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