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Protein

Conotoxin Bu21

Gene
N/A
Organism
Conus bullatus (Bubble cone)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel impairing toxin, Neurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Bu21
OrganismiConus bullatus (Bubble cone)
Taxonomic identifieri89438 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeConus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PropeptideiPRO_0000409967‹1 – 21Add BLAST›21
PeptideiPRO_000040996822 – 36Conotoxin Bu21Add BLAST15

Post-translational modificationi

Contains 2 disulfide bonds (By similarity). They are not indicated here, since framework I presents two different connectivities (I-III, II-IV and I-IV, II-III).By similarity

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom duct.

Family & Domainsi

Domaini

The cysteine framework is I (CC-C-C). Alpha4/5 pattern.

Sequence similaritiesi

Belongs to the conotoxin A superfamily.Curated

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0CY76-1 [UniParc]FASTAAdd to basket

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        10         20         30 
DGANAEATDN KPGVFERDEK KCCWNRACTR LVPCSK
Length:36
Mass (Da):4,014
Last modified:June 28, 2011 - v1
Checksum:iB144CC3A2274B065
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Entry informationi

Entry nameiCA121_CONBU
AccessioniPrimary (citable) accession number: P0CY76
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 22, 2017
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families