ID   KRE1_CANAL              Reviewed;         130 AA.
AC   P0CY22; A0A1D8PSK1; P28874; Q5A011;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=Protein KRE1;
DE   Flags: Precursor;
GN   Name=KRE1; OrderedLocusNames=CAALFM_CR03790CA;
GN   ORFNames=CaO19.11855, CaO19.4377, orf19.4349.6;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Involved in cell wall 1,6-beta-glucan assembly possibly by
CC       the addition of linear side chains of 1,6-linked Glc units to a highly
CC       branched 1,6- and 1,3-linked glucan backbone. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC       anchor {ECO:0000305}. Secreted, cell wall {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KRE1 family. {ECO:0000305}.
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DR   EMBL; CP017630; AOW31117.1; -; Genomic_DNA.
DR   RefSeq; XP_715153.1; XM_710060.2.
DR   AlphaFoldDB; P0CY22; -.
DR   STRING; 237561.P0CY22; -.
DR   GlyCosmos; P0CY22; 1 site, No reported glycans.
DR   EnsemblFungi; CR_03790C_A-T; CR_03790C_A-T-p1; CR_03790C_A.
DR   GeneID; 3643180; -.
DR   KEGG; cal:CAALFM_CR03790CA; -.
DR   CGD; CAL0000185859; KRE1.
DR   VEuPathDB; FungiDB:CR_03790C_A; -.
DR   eggNOG; ENOG502SFZS; Eukaryota.
DR   HOGENOM; CLU_156717_1_0_1; -.
DR   InParanoid; P0CY22; -.
DR   OMA; MGIQSSI; -.
DR   OrthoDB; 2004337at2759; -.
DR   PRO; PR:P0CY22; -.
DR   Proteomes; UP000000559; Chromosome R.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006078; P:(1->6)-beta-D-glucan biosynthetic process; IGI:CGD.
DR   GO; GO:0031505; P:fungal-type cell wall organization; IEA:InterPro.
DR   InterPro; IPR031452; Kre1.
DR   Pfam; PF17056; KRE1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cell wall; Cell wall biogenesis/degradation; Glycoprotein;
KW   GPI-anchor; Lipoprotein; Membrane; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..130
FT                   /note="Protein KRE1"
FT                   /id="PRO_0000021560"
FT   CARBOHYD        109
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   130 AA;  13856 MW;  C83C236DDFCD21C1 CRC64;
     MNVNSVIYYI LFLFASTILA ADKTSSSVSP TLVWVTGTDA NGKLATTQST YYQSFMSTYT
     TAETPSSGSI GLGSISGTVG EIRTYSMTTI SQGNGGLSKF NQNGLEMKNL SFVKLIGVSF
     IAFISFILLI
//