P0CY22 (KRE1_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein KRE1

Gene names

Name:	KRE1
ORF Names:	CaO19.11855, CaO19.4377, orf19.4349.6

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida › Candida albicans

Protein attributes

Sequence length	130 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in cell wall 1,6-beta-glucan assembly possibly by the addition of linear side chains of 1,6-linked Glc units to a highly branched 1,6- and 1,3-linked glucan backbone By similarity.
Subcellular location	Cell membrane; Lipid-anchor › GPI-anchor Potential. Secreted › cell wall By similarity.
Sequence similarities	To yeast KRE1.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Cell membrane Cell wall Membrane Secreted
Domain	Signal
PTM	GPI-anchor Glycoprotein Lipoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	(1->6)-beta-D-glucan biosynthetic process Inferred from genetic interaction PubMed 1938890. Source: CGD
Cellular_component	anchored to membrane Inferred from electronic annotation. Source: UniProtKB-KW cell surface Inferred from sequence or structural similarity PubMed 12845604. Source: CGD cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 130	110	Protein KRE1		PRO_0000021560
Amino acid modifications
	Glycosylation	109	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P0CY22 [UniParc]. Last modified October 19, 2011. Version 1. Checksum: C83C236DDFCD21C1	FASTA	130	13,856
	10 20 30 40 50 60 MNVNSVIYYI LFLFASTILA ADKTSSSVSP TLVWVTGTDA NGKLATTQST YYQSFMSTYT 70 80 90 100 110 120 TAETPSSGSI GLGSISGTVG EIRTYSMTTI SQGNGGLSKF NQNGLEMKNL SFVKLIGVSF 130 IAFISFILLI

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000091 Genomic DNA. Translation: EAK96068.1. AACQ01000090 Genomic DNA. Translation: EAK96120.1.
RefSeq	XP_715102.1. XM_710009.1. XP_715153.1. XM_710060.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3643180. 3643244.
KEGG	cal:CaO19.11855. cal:CaO19.4377.
Organism-specific databases
CGD	CAF0007009. orf19.4349.6.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

KRE1_CANAL

Accession

Primary (citable) accession number: P0CY22
Secondary accession number(s): P28874, Q5A011

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 19, 2011
Last sequence update:	October 19, 2011
Last modified:	March 6, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program