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P0CX32

- RS24B_YEAST

UniProt

P0CX32 - RS24B_YEAST

Protein

40S ribosomal protein S24-B

Gene

RPS24B

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. structural constituent of ribosome Source: SGD

    GO - Biological processi

    1. cytoplasmic translation Source: SGD
    2. maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31336-MONOMER.
    ReactomeiREACT_188965. SRP-dependent cotranslational protein targeting to membrane.
    REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_217188. Formation of a pool of free 40S subunits.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S24-B
    Alternative name(s):
    RP50
    Gene namesi
    Name:RPS24B
    Synonyms:RPS24EB
    Ordered Locus Names:YIL069C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome IX

    Organism-specific databases

    CYGDiYIL069c.
    SGDiS000001331. RPS24B.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytosolic small ribosomal subunit Source: SGD

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed2 Publications
    Chaini2 – 13513440S ribosomal protein S24-BPRO_0000409762Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylserine2 Publications
    Modified residuei14 – 141Phosphoserine1 Publication
    Modified residuei56 – 561Phosphoserine1 Publication

    Post-translational modificationi

    N-terminally acetylated by acetyltransferase NatA. Also partially acetylated by NatC.2 Publications

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Interactioni

    Subunit structurei

    Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

    Protein-protein interaction databases

    BioGridi34923. 120 interactions.
    36817. 191 interactions.
    IntActiP0CX32. 1 interaction.
    MINTiMINT-2782358.

    Structurei

    3D structure databases

    ProteinModelPortaliP0CX32.
    SMRiP0CX32. Positions 2-135.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S24e family.Curated

    Phylogenomic databases

    GeneTreeiENSGT00390000000153.
    KOiK02974.
    OrthoDBiEOG7ZD27J.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    HAMAPiMF_00545. Ribosomal_S24e.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR012678. Ribosomal_L23/L15e_core_dom.
    IPR001976. Ribosomal_S24e.
    IPR018098. Ribosomal_S24e_CS.
    [Graphical view]
    PANTHERiPTHR10496. PTHR10496. 1 hit.
    PfamiPF01282. Ribosomal_S24e. 1 hit.
    [Graphical view]
    ProDomiPD006052. Ribosomal_S24e. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF54189. SSF54189. 1 hit.
    PROSITEiPS00529. RIBOSOMAL_S24E. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P0CX32-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDAVTIRTR KVISNPLLAR KQFVVDVLHP NRANVSKDEL REKLAEVYKA    50
    EKDAVSVFGF RTQFGGGKSV GFGLVYNSVA EAKKFEPTYR LVRYGLAEKV 100
    EKASRQQRKQ KKNRDKKIFG TGKRLAKKVA RRNAD 135
    Length:135
    Mass (Da):15,329
    Last modified:June 28, 2011 - v1
    Checksum:i81B82D361207442A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti16 – 161P → D AA sequence (PubMed:1544921)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z38060 Genomic DNA. Translation: CAA86154.1.
    BK006942 Genomic DNA. Translation: DAA08481.1.
    PIRiS48410.
    RefSeqiNP_010997.3. NM_001178965.3.
    NP_012195.1. NM_001179419.1.

    Genome annotation databases

    EnsemblFungiiYER074W; YER074W; YER074W.
    YIL069C; YIL069C; YIL069C.
    GeneIDi854741.
    856805.
    KEGGisce:YER074W.
    sce:YIL069C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z38060 Genomic DNA. Translation: CAA86154.1 .
    BK006942 Genomic DNA. Translation: DAA08481.1 .
    PIRi S48410.
    RefSeqi NP_010997.3. NM_001178965.3.
    NP_012195.1. NM_001179419.1.

    3D structure databases

    ProteinModelPortali P0CX32.
    SMRi P0CX32. Positions 2-135.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 34923. 120 interactions.
    36817. 191 interactions.
    IntActi P0CX32. 1 interaction.
    MINTi MINT-2782358.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YER074W ; YER074W ; YER074W .
    YIL069C ; YIL069C ; YIL069C .
    GeneIDi 854741.
    856805.
    KEGGi sce:YER074W.
    sce:YIL069C.

    Organism-specific databases

    CYGDi YIL069c.
    SGDi S000001331. RPS24B.

    Phylogenomic databases

    GeneTreei ENSGT00390000000153.
    KOi K02974.
    OrthoDBi EOG7ZD27J.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31336-MONOMER.
    Reactomei REACT_188965. SRP-dependent cotranslational protein targeting to membrane.
    REACT_189050. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
    REACT_189183. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_217188. Formation of a pool of free 40S subunits.

    Miscellaneous databases

    NextBioi 977455.
    PROi P0CX32.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    HAMAPi MF_00545. Ribosomal_S24e.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR012678. Ribosomal_L23/L15e_core_dom.
    IPR001976. Ribosomal_S24e.
    IPR018098. Ribosomal_S24e_CS.
    [Graphical view ]
    PANTHERi PTHR10496. PTHR10496. 1 hit.
    Pfami PF01282. Ribosomal_S24e. 1 hit.
    [Graphical view ]
    ProDomi PD006052. Ribosomal_S24e. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF54189. SSF54189. 1 hit.
    PROSITEi PS00529. RIBOSOMAL_S24E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. "NH2-terminal acetylation of ribosomal proteins of Saccharomyces cerevisiae."
      Takakura H., Tsunasawa S., Miyagi M., Warner J.R.
      J. Biol. Chem. 267:5442-5445(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-16, ACETYLATION AT SER-2 BY NATA.
    4. "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
      Planta R.J., Mager W.H.
      Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NOMENCLATURE, SUBUNIT.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    8. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
      Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
      Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-56, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    9. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    10. "Sites of ubiquitin attachment in Saccharomyces cerevisiae."
      Starita L.M., Lo R.S., Eng J.K., von Haller P.D., Fields S.
      Proteomics 12:236-240(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiRS24B_YEAST
    AccessioniPrimary (citable) accession number: P0CX32
    Secondary accession number(s): D3DLX9, P26782
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 6160 molecules/cell in log phase SD medium.1 Publication
    There are 2 genes for S24 in yeast.

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Ribosomal proteins
      Ribosomal proteins families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families
    3. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    4. Yeast chromosome IX
      Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

    External Data

    Dasty 3