P0CX18 (YA066_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative GPI-anchored protein YAR066W

Gene names

Ordered Locus Names:

YAR066W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	203 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location

Cell membrane; Lipid-anchor › GPI-anchor Potential Ref.5.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal
PTM	GPI-anchor Glycoprotein Lipoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	anchored to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 184	161	Putative GPI-anchored protein YAR066W		PRO_0000202945
	Propeptide	185 – 203	19	Removed in mature form Potential		PRO_0000409753
Regions
	Compositional bias	25 – 57	33	Ser-rich
Amino acid modifications
	Lipidation	184	1	GPI-anchor amidated asparagine Potential
	Glycosylation	28	1	N-linked (GlcNAc...) Potential
	Glycosylation	138	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P0CX18 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 466EC45BEECCC69C	FASTA	203	20,594
	10 20 30 40 50 60 MFNRFNKFQA AVALALLSRG ALGDSYTNST SSADLSSITS VSSASASATA SDSLSSSDGT 70 80 90 100 110 120 VYLPSTTISG DLTVTGKVIA TEAVEVAAGG KLTLLDGEKY VFSSDLKVHG DLVVEKSEAS 130 140 150 160 170 180 YEGTAFDVSG ETFEVSGNFS AEETGAVSAS IYSFTPSSFK SSGDISLSLS KAKKGEVTFS 190 200 PYSNAGTFSL SNAILNGGSV SGL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 52 Kbp CDC15-FLO1-PHO11-YAR074 region." Bussey H., Keng T., Storms R.K., Vo D., Zhong W., Fortin N., Barton A.B., Kaback D.B., Clark M.W. Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"The nucleotide sequence of chromosome I from Saccharomyces cerevisiae." Bussey H., Kaback D.B., Zhong W.-W., Vo D.H., Clark M.W., Fortin N., Hall J., Ouellette B.F.F., Keng T., Barton A.B., Su Y., Davies C.J., Storms R.K. Proc. Natl. Acad. Sci. U.S.A. 92:3809-3813(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[5]	"Genome-wide identification of fungal GPI proteins." De Groot P.W., Hellingwerf K.J., Klis F.M. Yeast 20:781-796(2003) [PubMed] [Europe PMC] [Abstract] Cited for: PUTATIVE GPI-ANCHOR.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L28920 Genomic DNA. Translation: AAC09510.1. AY692573 Genomic DNA. Translation: AAT92592.1. BK006935 Genomic DNA. Translation: DAA07009.1.
PIR	S48995.
RefSeq	NP_009430.1. NM_001180045.1. NP_012084.3. NM_001179345.3.
3D structure databases
ProteinModelPortal	P0CX18.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YAR066W; YAR066W; YAR066W. YHR214W; YHR214W; YHR214W.
GeneID	851295. 856621.
KEGG	sce:YAR066W. sce:YHR214W.
Organism-specific databases
CYGD	YAR066w.
SGD	S000002144. YAR066W.
Enzyme and pathway databases
BioCyc	YEAST:G3O-28895-MONOMER.
Gene expression databases
ArrayExpress	P0CX18.
GermOnline	YAR066W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	968301.

Entry information

Entry name

YA066_YEAST

Accession

Primary (citable) accession number: P0CX18
Secondary accession number(s): D3DLG5, P38897, Q7LII8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	May 29, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program