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P0CW22

- RS17L_HUMAN

UniProt

P0CW22 - RS17L_HUMAN

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Protein

40S ribosomal protein S17-like

Gene

RPS17L

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: UniProtKB
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S17-like
Gene namesi
Name:RPS17L
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:40029. RPS17L.

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 13513440S ribosomal protein S17-likePRO_0000410726Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei113 – 1131Phosphoserine4 Publications
Modified residuei130 – 1301Phosphothreonine2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP0CW22.
PRIDEiP0CW22.

PTM databases

PhosphoSiteiP0CW22.

Expressioni

Gene expression databases

BgeeiP0CW22.
ExpressionAtlasiP0CW22. baseline.

Organism-specific databases

HPAiHPA055060.

Interactioni

Protein-protein interaction databases

BioGridi112132. 74 interactions.
1527840. 16 interactions.
IntActiP0CW22. 3 interactions.
MINTiMINT-8395037.

Structurei

3D structure databases

ProteinModelPortaliP0CW22.
SMRiP0CW22. Positions 1-129.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S17e family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000006548.
InParanoidiP0CW22.
KOiK02962.
OrthoDBiEOG72C52C.
PhylomeDBiP0CW22.
TreeFamiTF317992.

Family and domain databases

Gene3Di1.10.60.20. 1 hit.
HAMAPiMF_00511. Ribosomal_S17e.
InterProiIPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
[Graphical view]
PANTHERiPTHR10732. PTHR10732. 1 hit.
PfamiPF00833. Ribosomal_S17e. 1 hit.
[Graphical view]
SUPFAMiSSF116820. SSF116820. 1 hit.
PROSITEiPS00712. RIBOSOMAL_S17E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0CW22-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGRVRTKTVK KAARVIIEKY YTRLGNDFHT NKRVCEEIAI IPSKKLRNKI
60 70 80 90 100
AGYVTHLMKR IQRGPVRGIS IKLQEEERER RDNYVPEVSA LDQEIIEVDP
110 120 130
DTKEMLKLLD FGSLSNLQVT QPTVGMNFKT PRGPV
Length:135
Mass (Da):15,550
Last modified:June 28, 2011 - v1
Checksum:i299AD605C5401325
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC010724 Genomic DNA. No translation available.
RefSeqiNP_001012.1. NM_001021.4.
UniGeneiHs.433427.
Hs.512525.

Genome annotation databases

GeneIDi6218.
KEGGihsa:6218.
UCSCiuc002bhr.1. human.

Polymorphism databases

DMDMi338819320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC010724 Genomic DNA. No translation available.
RefSeqi NP_001012.1. NM_001021.4.
UniGenei Hs.433427.
Hs.512525.

3D structure databases

ProteinModelPortali P0CW22.
SMRi P0CW22. Positions 1-129.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 112132. 74 interactions.
1527840. 16 interactions.
IntActi P0CW22. 3 interactions.
MINTi MINT-8395037.

PTM databases

PhosphoSitei P0CW22.

Polymorphism databases

DMDMi 338819320.

Proteomic databases

MaxQBi P0CW22.
PRIDEi P0CW22.

Protocols and materials databases

DNASUi 6218.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 6218.
KEGGi hsa:6218.
UCSCi uc002bhr.1. human.

Organism-specific databases

CTDi 6218.
GeneCardsi GC15M083202.
HGNCi HGNC:40029. RPS17L.
HPAi HPA055060.
neXtProti NX_P0CW22.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00390000006548.
InParanoidi P0CW22.
KOi K02962.
OrthoDBi EOG72C52C.
PhylomeDBi P0CW22.
TreeFami TF317992.

Miscellaneous databases

ChiTaRSi RPS17L. human.
NextBioi 24145.
PROi P0CW22.

Gene expression databases

Bgeei P0CW22.
ExpressionAtlasi P0CW22. baseline.

Family and domain databases

Gene3Di 1.10.60.20. 1 hit.
HAMAPi MF_00511. Ribosomal_S17e.
InterProi IPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
[Graphical view ]
PANTHERi PTHR10732. PTHR10732. 1 hit.
Pfami PF00833. Ribosomal_S17e. 1 hit.
[Graphical view ]
SUPFAMi SSF116820. SSF116820. 1 hit.
PROSITEi PS00712. RIBOSOMAL_S17E. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113 AND THR-130, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113 AND THR-130, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRS17L_HUMAN
AccessioniPrimary (citable) accession number: P0CW22
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: June 28, 2011
Last modified: October 29, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3