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Protein

LIM and senescent cell antigen-like-containing domain protein 3-like

Gene

LIMS3L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
LIM and senescent cell antigen-like-containing domain protein 3-like
Gene namesi
Name:LIMS3L
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:39941. LIMS3L.

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi334350996.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 117117LIM and senescent cell antigen-like-containing domain protein 3-likePRO_0000409553Add
BLAST

Proteomic databases

PRIDEiP0CW20.

Expressioni

Gene expression databases

BgeeiP0CW20.
ExpressionAtlasiP0CW20. baseline.
GenevisibleiP0CW20. HS.

Organism-specific databases

HPAiHPA058455.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BCL6P411823EBI-10196832,EBI-765407
GMCL1P1Q8NEA93EBI-10196832,EBI-745707

Protein-protein interaction databases

BioGridi125178. 2 interactions.
IntActiP0CW20. 2 interactions.
STRINGi9606.ENSP00000405165.

Structurei

3D structure databases

ProteinModelPortaliP0CW20.
SMRiP0CW20. Positions 68-114.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini70 – 11748LIM zinc-bindingPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 LIM zinc-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

LIM domain

Phylogenomic databases

HOGENOMiHOG000070043.
InParanoidiP0CW20.

Family and domain databases

Gene3Di2.10.110.10. 1 hit.
InterProiIPR017351. PINCH.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR24210. PTHR24210. 1 hit.
PfamiPF00412. LIM. 1 hit.
[Graphical view]
SMARTiSM00132. LIM. 1 hit.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0CW20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFSGRARPC IIPENEEIPR AALNTVHEAN GTEDERAVSK LQRRHSDVKV
60 70 80 90 100
YKEFCDFYAK FNMANALASA TCERCKGGFA PAETIVNSNG ELYHEQCFVC
110
AQCFQQFPEG LFYEERT
Length:117
Mass (Da):13,251
Last modified:May 31, 2011 - v1
Checksum:iF260926C06DA51CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108938 Genomic DNA. Translation: AAY24131.1.
AC112229 Genomic DNA. No translation available.
CCDSiCCDS54387.1.
RefSeqiNP_001192217.1. NM_001205288.1.
NP_277049.1. NM_033514.4.
UniGeneiHs.535619.
Hs.735995.

Genome annotation databases

EnsembliENST00000413601; ENSP00000404432; ENSG00000256671.
GeneIDi100288695.
96626.
KEGGihsa:100288695.
hsa:96626.
UCSCiuc002tff.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108938 Genomic DNA. Translation: AAY24131.1.
AC112229 Genomic DNA. No translation available.
CCDSiCCDS54387.1.
RefSeqiNP_001192217.1. NM_001205288.1.
NP_277049.1. NM_033514.4.
UniGeneiHs.535619.
Hs.735995.

3D structure databases

ProteinModelPortaliP0CW20.
SMRiP0CW20. Positions 68-114.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125178. 2 interactions.
IntActiP0CW20. 2 interactions.
STRINGi9606.ENSP00000405165.

Polymorphism and mutation databases

DMDMi334350996.

Proteomic databases

PRIDEiP0CW20.

Protocols and materials databases

DNASUi96626.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413601; ENSP00000404432; ENSG00000256671.
GeneIDi100288695.
96626.
KEGGihsa:100288695.
hsa:96626.
UCSCiuc002tff.3. human.

Organism-specific databases

CTDi100288695.
96626.
GeneCardsiGC02M111204.
HGNCiHGNC:39941. LIMS3L.
HPAiHPA058455.
neXtProtiNX_P0CW20.
GenAtlasiSearch...

Phylogenomic databases

HOGENOMiHOG000070043.
InParanoidiP0CW20.

Miscellaneous databases

NextBioi20778441.
PROiP0CW20.

Gene expression databases

BgeeiP0CW20.
ExpressionAtlasiP0CW20. baseline.
GenevisibleiP0CW20. HS.

Family and domain databases

Gene3Di2.10.110.10. 1 hit.
InterProiIPR017351. PINCH.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR24210. PTHR24210. 1 hit.
PfamiPF00412. LIM. 1 hit.
[Graphical view]
SMARTiSM00132. LIM. 1 hit.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiLIM3L_HUMAN
AccessioniPrimary (citable) accession number: P0CW20
Secondary accession number(s): C9K0W2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 31, 2011
Last sequence update: May 31, 2011
Last modified: July 22, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.