Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

LIM and senescent cell antigen-like-containing domain protein 4

Gene

LIMS4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
LIM and senescent cell antigen-like-containing domain protein 4
Alternative name(s):
LIM and senescent cell antigen-like-containing domain protein 3-like
Gene namesi
Name:LIMS4Imported
Synonyms:LIMS3L
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:39941. LIMS4.

Pathology & Biotechi

Organism-specific databases

DisGeNETi100288695.
96626.
OpenTargetsiENSG00000256671.
ENSG00000256977.

Polymorphism and mutation databases

DMDMi334350996.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004095531 – 117LIM and senescent cell antigen-like-containing domain protein 4Add BLAST117

Proteomic databases

MaxQBiP0CW20.
PaxDbiP0CW20.
PeptideAtlasiP0CW20.
PRIDEiP0CW20.

Expressioni

Gene expression databases

BgeeiENSG00000256671.
ExpressionAtlasiP0CW20. differential.
GenevisibleiP0CW20. HS.

Organism-specific databases

HPAiHPA058455.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BCL6P411823EBI-10196832,EBI-765407
GMCL1P1Q8NEA93EBI-10196832,EBI-745707

Protein-protein interaction databases

BioGridi125178. 2 interactors.
IntActiP0CW20. 2 interactors.
STRINGi9606.ENSP00000405165.

Structurei

3D structure databases

ProteinModelPortaliP0CW20.
SMRiP0CW20.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 117LIM zinc-bindingPROSITE-ProRule annotationAdd BLAST48

Sequence similaritiesi

Contains 1 LIM zinc-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

LIM domain

Phylogenomic databases

eggNOGiENOG410JC6F. Eukaryota.
ENOG41119KQ. LUCA.
GeneTreeiENSGT00760000118910.
HOGENOMiHOG000070043.
InParanoidiP0CW20.
OrthoDBiEOG091G0ZC9.

Family and domain databases

Gene3Di2.10.110.10. 1 hit.
InterProiIPR017351. PINCH.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR24210. PTHR24210. 1 hit.
PfamiPF00412. LIM. 1 hit.
[Graphical view]
SMARTiSM00132. LIM. 1 hit.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0CW20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFSGRARPC IIPENEEIPR AALNTVHEAN GTEDERAVSK LQRRHSDVKV
60 70 80 90 100
YKEFCDFYAK FNMANALASA TCERCKGGFA PAETIVNSNG ELYHEQCFVC
110
AQCFQQFPEG LFYEERT
Length:117
Mass (Da):13,251
Last modified:May 31, 2011 - v1
Checksum:iF260926C06DA51CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108938 Genomic DNA. Translation: AAY24131.1.
AC112229 Genomic DNA. No translation available.
CCDSiCCDS54387.1.
RefSeqiNP_001192217.1. NM_001205288.1.
NP_277049.1. NM_033514.4.
UniGeneiHs.535619.
Hs.735995.

Genome annotation databases

EnsembliENST00000413601; ENSP00000404432; ENSG00000256671.
GeneIDi100288695.
96626.
KEGGihsa:100288695.
hsa:96626.
UCSCiuc002tff.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108938 Genomic DNA. Translation: AAY24131.1.
AC112229 Genomic DNA. No translation available.
CCDSiCCDS54387.1.
RefSeqiNP_001192217.1. NM_001205288.1.
NP_277049.1. NM_033514.4.
UniGeneiHs.535619.
Hs.735995.

3D structure databases

ProteinModelPortaliP0CW20.
SMRiP0CW20.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125178. 2 interactors.
IntActiP0CW20. 2 interactors.
STRINGi9606.ENSP00000405165.

Polymorphism and mutation databases

DMDMi334350996.

Proteomic databases

MaxQBiP0CW20.
PaxDbiP0CW20.
PeptideAtlasiP0CW20.
PRIDEiP0CW20.

Protocols and materials databases

DNASUi96626.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413601; ENSP00000404432; ENSG00000256671.
GeneIDi100288695.
96626.
KEGGihsa:100288695.
hsa:96626.
UCSCiuc002tff.4. human.

Organism-specific databases

CTDi100288695.
96626.
DisGeNETi100288695.
96626.
GeneCardsiLIMS3L.
HGNCiHGNC:39941. LIMS4.
HPAiHPA058455.
neXtProtiNX_P0CW20.
OpenTargetsiENSG00000256671.
ENSG00000256977.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JC6F. Eukaryota.
ENOG41119KQ. LUCA.
GeneTreeiENSGT00760000118910.
HOGENOMiHOG000070043.
InParanoidiP0CW20.
OrthoDBiEOG091G0ZC9.

Miscellaneous databases

PROiP0CW20.

Gene expression databases

BgeeiENSG00000256671.
ExpressionAtlasiP0CW20. differential.
GenevisibleiP0CW20. HS.

Family and domain databases

Gene3Di2.10.110.10. 1 hit.
InterProiIPR017351. PINCH.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR24210. PTHR24210. 1 hit.
PfamiPF00412. LIM. 1 hit.
[Graphical view]
SMARTiSM00132. LIM. 1 hit.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLIMS4_HUMAN
AccessioniPrimary (citable) accession number: P0CW20
Secondary accession number(s): C9K0W2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 31, 2011
Last sequence update: May 31, 2011
Last modified: November 30, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.