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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2563-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Ordered Locus Names:MM_2505
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000000595 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 619619Chaperone protein DnaKPRO_0000408039Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi192952.MM_2505.

Structurei

3D structure databases

ProteinModelPortaliP0CW13.
SMRiP0CW13. Positions 1-509.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiarCOG03060. Archaea.
COG0443. LUCA.
HOGENOMiHOG000228137.
KOiK04043.
OMAiEKMAPPQ.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0CW13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKILGIDLG TTNSCVAVME GGEAVVIPNA EGSRTTPSVV GFSKKGEKLV
60 70 80 90 100
GQVAKRQAIS NPDNTVYSIK RHMGEANYKV TLNGKDYTPQ EISAMILQKL
110 120 130 140 150
KADAEAYLGE TIKQAVITVP AYFNDSQRQA TKDAGAIAGL EVLRIINEPT
160 170 180 190 200
AASLAYGLDK GDIDQKILVY DLGGGTFDVS ILELGGGVFE VKSTSGDTHL
210 220 230 240 250
GGDDFDQRVI DYLLAEFKKS EGIDLSKDKA VLQRLKDAAE KAKIELSGVA
260 270 280 290 300
NTNINLPFLT VGTDGEPKHM DIDLTRAQFQ KMTEDLLEKT LVSMRRALSD
310 320 330 340 350
AKLTPNDLDK VILVGGATRM PAVVELVENF TGKKPYKNIN PDEAVAIGAA
360 370 380 390 400
IQAGVLGGEV KDVLLLDVTP LTLGIETLGG IATPLIQRNT TIPTKKSQIF
410 420 430 440 450
STAADNQPSV EIHVLQGERG IASENKTLGR FILDGIPPAP RGIPQIEVTF
460 470 480 490 500
DIDANGILHV SAKDLGTGKQ QSISIQKPGG LSDDEIERMV KDAEMHAEED
510 520 530 540 550
RKRKEEVEIR NNAEALINAA EKTIKEAGDL ATEDQKSKVN AAIEDLKKAL
560 570 580 590 600
EGKDAEDIKA KTEALQESVY PISTAMYQKA QQAQQAAGGE GGAAGTDARG
610
PDETVVDADY EVVDDEKRK
Length:619
Mass (Da):66,288
Last modified:May 3, 2011 - v1
Checksum:iAFF412BEAF957E39
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM32201.1.
RefSeqiWP_011034423.1. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM32201; AAM32201; MM_2505.
GeneIDi24882230.
KEGGimma:MM_2505.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM32201.1.
RefSeqiWP_011034423.1. NC_003901.1.

3D structure databases

ProteinModelPortaliP0CW13.
SMRiP0CW13. Positions 1-509.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi192952.MM_2505.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM32201; AAM32201; MM_2505.
GeneIDi24882230.
KEGGimma:MM_2505.

Phylogenomic databases

eggNOGiarCOG03060. Archaea.
COG0443. LUCA.
HOGENOMiHOG000228137.
KOiK04043.
OMAiEKMAPPQ.

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2563-MONOMER.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiDNAK_METMA
AccessioniPrimary (citable) accession number: P0CW13
Secondary accession number(s): P27094
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: May 3, 2011
Last modified: November 11, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.