Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P0CT24

- GLU2B_USTMA

UniProt

P0CT24 - GLU2B_USTMA

Protein

Glucosidase 2 subunit beta

Gene

UM12045

Organism
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 6 (01 Oct 2014)
      Sequence version 1 (16 Oct 2013)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc2Man9GlcNAc2 oligosaccharide precursor of immature glycoproteins in the endoplasmic reticulum (ER). Specifically required for the cleavage of the final glucose. The subunit beta retains the catalytic subunit alpha in the ER By similarity.By similarity

    GO - Biological processi

    1. N-glycan processing Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucosidase 2 subunit beta
    Alternative name(s):
    Alpha-glucosidase 2 subunit beta
    Gene namesi
    ORF Names:UM12045
    OrganismiUstilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
    Taxonomic identifieri237631 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaUstilaginomycetesUstilaginalesUstilaginaceaeUstilago
    ProteomesiUP000000561: Unassembled WGS sequence

    Subcellular locationi

    Endoplasmic reticulum PROSITE-ProRule annotation

    GO - Cellular componenti

    1. endoplasmic reticulum Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2626Sequence AnalysisAdd
    BLAST
    Chaini27 – 583557Glucosidase 2 subunit betaPRO_0000423830Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi91 ↔ 115By similarity

    Keywords - PTMi

    Disulfide bond

    Interactioni

    Subunit structurei

    Heterodimer of a catalytic subunit alpha and a subunit beta.

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili130 – 252123Sequence AnalysisAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi580 – 5834Prevents secretion from ERPROSITE-ProRule annotation

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi564 – 57310Poly-Gln

    Keywords - Domaini

    Coiled coil, Signal

    Phylogenomic databases

    eggNOGiNOG289998.

    Family and domain databases

    Gene3Di2.70.130.10. 2 hits.
    InterProiIPR026874. Glucosidase_2_bsu.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR009011. Man6P_isomerase_rcpt-bd_dom.
    IPR028146. PRKCSH_N.
    [Graphical view]
    PANTHERiPTHR12630:SF1. PTHR12630:SF1. 1 hit.
    PfamiPF12999. PRKCSH-like. 1 hit.
    [Graphical view]
    SMARTiSM00192. LDLa. 1 hit.
    [Graphical view]
    SUPFAMiSSF50911. SSF50911. 1 hit.
    PROSITEiPS00014. ER_TARGET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P0CT24-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVRLNLAVVA LAAGALSASA SASSSATPLR GLLTDAAKYQ PTKDAQSQLR    50
    WKCLDGSKEL SWSAVNDDYC DCPDGSDEPG TSACPNSSFY CHNTGHMPAY 100
    IRSSRVDDGI CDPECCDGSD ESDGKIRCPN RCEKVGKEYR KKLAELDNLR 150
    RAGAKVRDKY IAEGRKQKEL LHAEIAKLEI EVQVATENEA RFKAELTRAE 200
    TSDKALIDAK VKTPLYTKLV DYQNAIRALH VKNAALKAEL QTLTLLLDDL 250
    AKGYNPNYQD MAVKGAVVAY KEWRGIASAA AAATATGEVK EEGENNVDQI 300
    AGENTKLNEL LDEGDWPWAK LSTLLSDDPL DLMDRGLGGA LDDKRVYASE 350
    TDGGLLFRIH EYLPDGIVPY FEAMVDTLLD VLMKANVITD VKRMRPKSSV 400
    GSESEPETVS VARRAHTDAA AHLSRTTHEL SSLKQKLSEF STRYGRSAEF 450
    KALENKCFSK DMGEYTYEYC FFGRATQIPN NGGAQISLGT FTNFNPKHDK 500
    SADEDAYWLQ QIYARGQKCW NGPERSAIVD LECSTENKVL DVFEAEKCIY 550
    SIKVATPAVC FPPQQQQAQQ TQQDGGHQVK DEL 583
    Length:583
    Mass (Da):64,265
    Last modified:October 16, 2013 - v1
    Checksum:iE42B01F4B737BC43
    GO

    Sequence cautioni

    The sequence EAK87151.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene UM06444 has been split into 3 genes: UM12045, UM12046 and UM12047.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACP01000249 Genomic DNA. Translation: EAK87151.1. Sequence problems.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACP01000249 Genomic DNA. Translation: EAK87151.1 . Sequence problems.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG289998.

    Family and domain databases

    Gene3Di 2.70.130.10. 2 hits.
    InterProi IPR026874. Glucosidase_2_bsu.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR009011. Man6P_isomerase_rcpt-bd_dom.
    IPR028146. PRKCSH_N.
    [Graphical view ]
    PANTHERi PTHR12630:SF1. PTHR12630:SF1. 1 hit.
    Pfami PF12999. PRKCSH-like. 1 hit.
    [Graphical view ]
    SMARTi SM00192. LDLa. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50911. SSF50911. 1 hit.
    PROSITEi PS00014. ER_TARGET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis."
      Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J.
      , Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L., Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J., Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P., Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G., Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A., Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W.
      Nature 444:97-101(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 521 / FGSC 9021.

    Entry informationi

    Entry nameiGLU2B_USTMA
    AccessioniPrimary (citable) accession number: P0CT24
    Secondary accession number(s): Q4P0B9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 16, 2013
    Last sequence update: October 16, 2013
    Last modified: October 1, 2014
    This is version 6 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3