Chitin deacetylase precursor - Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)

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P0CP77 (CDA_CRYNB) Reviewed, UniProtKB/Swiss-Prot

Last modified March 6, 2013. Version 7. History...

Clusters with 100%, 90%, 50% identity |

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Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Chitin deacetylase
EC=3.5.1.41

Gene names

Name:	MP 84
Ordered Locus Names:	CNBD2750

Organism

Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans) [Complete proteome]

Taxonomic identifier

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Tremellomycetes › Tremellales › Tremellaceae › Filobasidiella › Filobasidiella/Cryptococcus neoformans species complex ›

Protein attributes

Sequence length	410 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin.
Catalytic activity	Chitin + H₂O = chitosan + acetate.
Sequence similarities	Belongs to the polysaccharide deacetylase family.

Ontologies

Keywords
Domain	Signal
Molecular function	Hydrolase
PTM	Cleavage on pair of basic residues Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	chitin deacetylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

18

Potential

Propeptide

21

By similarity

PRO_0000410197

Chain

371

Chitin deacetylase

PRO_0000410198

Amino acid modifications

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Sequences

Sequence

Length

Mass (Da)

Tools

P0CP77 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: 807AEC6CFB476652
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410

43,993

        10         20         30         40         50         60 
MYGHLSLSTL SLLAVVAAAP FHESWLQPRD SDVSQLFRRG APDPKASDYL SYYPSPGSTP 

        70         80         90        100        110        120 
NVSTIPQAWL DKLATVQLPN VSVATANDGR PTYPNNENDG DSEICSFTDQ CYVEDDLYSP 

       130        140        150        160        170        180 
PGEKVWALSF DDGPTDVSPA LYDYLAQNNI SSSATHFMIG GNIITSPQSV LIAIEAGGHL 

       190        200        210        220        230        240 
AVHTWSHPYM TTLTNEQVVA ELGWTMQALS DLNGGRIPLY WRPPYGDVDN RVRAIAKGVF 

       250        260        270        280        290        300 
GLVTVLWDSD TNDWAISDQP DQYSVASVEA YFDTLVTGNR TQGLLLLEHE LDNNTVEVFE 

       310        320        330        340        350        360 
TEYPKAVANG WSVKNVADAF SMKWYLNSGK GNDDVVTTMS VAGTLTTAKP THTSTSVASA 

       370        380        390        400        410 
TATSSASVTD SAGVSIASAA SSQESSSWPI ANRPSLFVIA CGLALAAIMV

References

[1]

"The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans."
Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S.

expand/collapse author list

Hyman R.W.
Science 307:1321-1324(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B-3501A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAEY01000020 Genomic DNA. Translation: EAL21220.1.
RefSeq	XP_775867.1. XM_770774.1.
3D structure databases
ProteinModelPortal	P0CP77.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4935664.
KEGG	cnb:CNBD2750.
Family and domain databases
Gene3D	3.20.20.370. 1 hit.
InterPro	IPR011330. Glyco_hydro/deAcase_b/a-brl. IPR002509. Polysac_deacetylase. [Graphical view]
Pfam	PF01522. Polysacc_deac_1. 1 hit. [Graphical view]
SUPFAM	SSF88713. Glyco_hydro/deAcase_b/a-brl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CDA_CRYNB

Accession

Primary (citable) accession number: P0CP77
Secondary accession number(s): Q53I51, Q55U29, Q5KIB3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	March 6, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents