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P0CN84 (GLNA_CRYNJ) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

Short name=GS
EC=6.3.1.2
Alternative name(s):
Glutamate--ammonia ligase
Gene names
Name:GLN1
Synonyms:FGS
Ordered Locus Names:CNA04370
OrganismCryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) [Reference proteome]
Taxonomic identifier214684 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homooctamer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 358358Glutamine synthetase
PRO_0000153154

Experimental info

Sequence conflict2191A → P in CAD10037. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P0CN84 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: F159AE2CAA305ACB

FASTA35839,516
        10         20         30         40         50         60 
MSQLIATKRV DLLAPYLALD QGSRVQAEYI WIDAEGGIRS KTMTLDKAPS SVADLKEWNF 

        70         80         90        100        110        120 
DGSSTNQAPA DNSDVFLRPV AIFKDPFRGG ANILVLCECY DNDGTPNKSN YRAHCKKVMD 

       130        140        150        160        170        180 
AAKDTEPWFG LEQEYTLFDA DGQVFGWPKN GFPGPQGPYY CGVGAGKVFA RDFIEAHYRA 

       190        200        210        220        230        240 
CLYAGIKISG INAEVMPSQW EFQVGPCTGI EMGDHLWMAR FLLLRIGEEW GITPSLHPKP 

       250        260        270        280        290        300 
LKGDWNGAGC HSNYSTKDMR TPGKGMAAIE DAIKKLEKKH LEHIAVYGED NDLRLTGKHE 

       310        320        330        340        350 
TASMTTFSAG VANRGASIRI PRHVGAQGYG YLEDRRPASN VDPYRVTAIL VETTVLNN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ414581 mRNA. Translation: CAD10037.1.
AE017341 Genomic DNA. Translation: AAW40974.1.
AE017341 Genomic DNA. Translation: AAW40975.1.
RefSeqXP_566793.1. XM_566793.1.
XP_566794.1. XM_566794.1.
UniGeneFne.6557.

3D structure databases

ProteinModelPortalP0CN84.
SMRP0CN84. Positions 11-358.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiAAW40974; AAW40974; CNA04370.
AAW40975; AAW40975; CNA04370.
GeneID3253352.
KEGGcne:CNA04370.

Phylogenomic databases

KOK01915.
OrthoDBEOG7GTTD8.

Family and domain databases

Gene3D3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
PROSITEPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA_CRYNJ
AccessionPrimary (citable) accession number: P0CN84
Secondary accession number(s): D3NQ34 expand/collapse secondary AC list , Q55ZS0, Q5KP31, Q96UG9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 13, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families