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Protein

1,4-alpha-glucan-branching enzyme

Gene

GLC3

Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei342NucleophileBy similarity1
Active sitei397Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processGlycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan-branching enzyme (EC:2.4.1.18)
Alternative name(s):
Glycogen-branching enzyme
Gene namesi
Name:GLC3
Ordered Locus Names:CNBA3620
OrganismiCryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)
Taxonomic identifieri283643 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesCryptococcaceaeCryptococcusCryptococcus neoformans species complex
Proteomesi
  • UP000001435 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:CNBA3620

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004100961 – 6821,4-alpha-glucan-branching enzymeAdd BLAST682

Interactioni

Protein-protein interaction databases

STRINGi283643.XP_777893.1

Structurei

3D structure databases

ProteinModelPortaliP0CN83
SMRiP0CN83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0470 Eukaryota
COG0296 LUCA
HOGENOMiHOG000175159
KOiK00700
OrthoDBiEOG092C0QFK

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.1180, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 1 hit
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit

Sequencei

Sequence statusi: Complete.

P0CN83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAVSLSDGT AVLKTDPWLE PFSGALRERY AAYQKQRTII EEHEGGLAEF
60 70 80 90 100
SKGYKSMGFQ IDKNGGVRYR EWASNATEAR LIGEFNNWSH TANPMTKSPF
110 120 130 140 150
GVWECYVPPV SPGVCAIPHD SMVKISMTLP GGESIDRIPT WITRVTQDLN
160 170 180 190 200
ISPIYDGRFW NPPKEQQYQF KHGHSTRPVE GLKIYEAHVG ISSPNMRVTT
210 220 230 240 250
YKEFEVDVLP KIKQLGYNCI QMMAIMEHAY YASFGYQVTN FFAASSRFGT
260 270 280 290 300
PEELKSLVDK AHELGLTVLL DVVHSHASKN ILDGINMYDG SDHLYFHEGG
310 320 330 340 350
RGRHDQWDSR LFNYGQHEVL RFLLSNLRFW MDIYMFDGFR FDGVTSMMYK
360 370 380 390 400
HHGIGSGFSG GYHEYFGDSV DLEAMVYLML ANAMLHETYP HVVTIAEDVS
410 420 430 440 450
GMPTLCRPVA EGGVGFDYRL SMAIPDMWIK LLKEYTDDQW EMGQIVHNLT
460 470 480 490 500
NRRHLEKSVA YAESHDQALV GDKTLAFWLM DKEMYDFMSD LSPLTPIIDR
510 520 530 540 550
GLALHKMIRF IVHTLGGEAY LNFEGNEFGH PEWMDFPREG NGNSFAHARR
560 570 580 590 600
QFNLVDDKLL RYKYLYEFDV AMNWLEDKYK WLNSPQAYVS LKHEGDKMIV
610 620 630 640 650
FERAGLLFIF NFHPTQSFTD YRVGVDTAGE YKVILTSDET RFGGHNRIDM
660 670 680
GGRYFTTPME WNGRKNWLQV YSPSRTVLVL GL
Length:682
Mass (Da):78,344
Last modified:June 28, 2011 - v1
Checksum:iAD1D30BE01EB496F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEY01000002 Genomic DNA Translation: EAL23246.1
RefSeqiXP_777893.1, XM_772800.1

Genome annotation databases

EnsemblFungiiAAW40900; AAW40900; CNA03810
EAL23246; EAL23246; CNBA3620
GeneIDi4933620
KEGGicnb:CNBA3620

Similar proteinsi

Entry informationi

Entry nameiGLGB_CRYNB
AccessioniPrimary (citable) accession number: P0CN83
Secondary accession number(s): Q55ZX8, Q5KP87
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: June 28, 2011
Last modified: June 20, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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