ID   ST3L3_HUMAN             Reviewed;         134 AA.
AC   P0CL85; A6NMT8; A8K0A1; Q32NE4; Q6NXR2; Q7L5M5; Q7Z5K6;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-MAY-2011, sequence version 1.
DT   24-JAN-2024, entry version 60.
DE   RecName: Full=STAG3-like protein 3;
DE   AltName: Full=Stromal antigen 3-like protein 3;
GN   Name=STAG3L3;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RC   TISSUE=Testis;
RA   Xu Z.Y., Xu M., Yin L.L., Lu L., Li J.M., Zhou J.M., Sha J.H.;
RT   "An ARM-repeat superfamily protein acts in spermatogenesis.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   TISSUE=Brain, Mammary gland, and Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00750}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=P0CL85-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=P0CL85-2; Sequence=VSP_041016;
CC   -!- SIMILARITY: Belongs to the SCC3 family. {ECO:0000305}.
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DR   EMBL; AY313779; AAP81010.1; -; mRNA.
DR   EMBL; AC005488; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC066937; AAH66937.1; -; mRNA.
DR   AlphaFoldDB; P0CL85; -.
DR   SMR; P0CL85; -.
DR   iPTMnet; P0CL85; -.
DR   PhosphoSitePlus; P0CL85; -.
DR   BioMuta; HGNC:33845; -.
DR   DMDM; 332321727; -.
DR   MassIVE; P0CL85; -.
DR   PeptideAtlas; P0CL85; -.
DR   ProteomicsDB; 52511; -. [P0CL85-1]
DR   ProteomicsDB; 52512; -. [P0CL85-2]
DR   AGR; HGNC:33845; -.
DR   GeneCards; STAG3L3; -.
DR   HGNC; HGNC:33845; STAG3L3.
DR   neXtProt; NX_P0CL85; -.
DR   InParanoid; P0CL85; -.
DR   PathwayCommons; P0CL85; -.
DR   Pharos; P0CL85; Tdark.
DR   PRO; PR:P0CL85; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; P0CL85; Protein.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039662; Cohesin_Scc3/SA.
DR   InterPro; IPR020839; SCD.
DR   PANTHER; PTHR11199:SF8; COHESIN SUBUNIT SA-3; 1.
DR   PANTHER; PTHR11199; STROMAL ANTIGEN; 1.
DR   Pfam; PF21581; SCD; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS51425; SCD; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Nucleus; Reference proteome.
FT   CHAIN           1..134
FT                   /note="STAG3-like protein 3"
FT                   /id="PRO_0000408000"
FT   DOMAIN          10..95
FT                   /note="SCD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00750"
FT   VAR_SEQ         117..134
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.1"
FT                   /id="VSP_041016"
FT   CONFLICT        87
FT                   /note="C -> R (in Ref. 1; AAP81010 and 3; AAH66937)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   134 AA;  15609 MW;  6A7148BD316B9B72 CRC64;
     MIFSMLRKLP KVTCRDVLPE IRAICIEEIG CWMQSYSTSF LTDSYLKYIG WTLHDKHREV
     RVKCVKALKG LYGNRDLTAR LELFTGCFKD WMVSMIMDRE YSVAVEAVRL LILILKNMEG
     VLMDVDCESV YPIV
//