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Protein

Outer surface protein A

Gene

ospA

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Outer surface protein A
Gene namesi
Name:ospA
Ordered Locus Names:BB_A15
Encoded oniPlasmid lp540 Publication
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000001807 Componenti: Plasmid lp54

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Add BLAST16
ChainiPRO_000001807417 – 273Outer surface protein AAdd BLAST257

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi17N-palmitoyl cysteineCurated1
Lipidationi17S-diacylglycerol cysteineCurated1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PRIDEiP0CL66.

Structurei

Secondary structure

1273
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi26 – 28Combined sources3
Beta strandi30 – 34Combined sources5
Turni35 – 37Combined sources3
Beta strandi38 – 42Combined sources5
Beta strandi48 – 50Combined sources3
Beta strandi52 – 58Combined sources7
Beta strandi61 – 72Combined sources12
Beta strandi74 – 79Combined sources6
Beta strandi85 – 90Combined sources6
Beta strandi97 – 102Combined sources6
Beta strandi108 – 115Combined sources8
Turni117 – 119Combined sources3
Beta strandi121 – 126Combined sources6
Beta strandi132 – 138Combined sources7
Beta strandi144 – 149Combined sources6
Beta strandi152 – 154Combined sources3
Beta strandi156 – 162Combined sources7
Beta strandi165 – 171Combined sources7
Beta strandi173 – 182Combined sources10
Beta strandi185 – 192Combined sources8
Beta strandi197 – 203Combined sources7
Turni208 – 210Combined sources3
Beta strandi212 – 217Combined sources6
Turni218 – 221Combined sources4
Beta strandi222 – 227Combined sources6
Beta strandi230 – 237Combined sources8
Beta strandi243 – 248Combined sources6
Beta strandi252 – 255Combined sources4
Beta strandi260 – 262Combined sources3
Helixi265 – 271Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FJ1X-ray2.68E/F18-273[»]
1OSPX-ray1.95O18-273[»]
2AF5X-ray2.50A27-273[»]
2FKGX-ray2.40A27-273[»]
2FKJX-ray3.10A/B/C27-273[»]
2G8CX-ray1.15O27-273[»]
2HKDX-ray1.60A27-130[»]
A118-273[»]
2I5VX-ray1.10O27-273[»]
2I5ZX-ray1.20O27-273[»]
2OL6X-ray1.60O27-273[»]
2OL7X-ray1.35A/B27-273[»]
2OL8X-ray1.90O27-273[»]
2OY1X-ray1.86O27-273[»]
2OY5X-ray1.80O27-273[»]
2OY7X-ray1.55A27-130[»]
A119-273[»]
2OY8X-ray2.00A27-273[»]
2OYBX-ray1.30O27-273[»]
2PI3X-ray1.40O27-273[»]
3AUMX-ray1.60O27-273[»]
SMRiP0CL66.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0CL66.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

OMAiALIACKQ.

Family and domain databases

Gene3Di3.90.930.1. 1 hit.
InterProiIPR001809. OM_lipoprot_Borrelia.
IPR023322. OM_lipoprot_dom.
[Graphical view]
PfamiPF00820. Lipoprotein_1. 1 hit.
[Graphical view]
PRINTSiPR00968. OUTRSURFACE.
ProDomiPD001127. OM_lipoprot_Borrelia. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF51087. SSF51087. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0CL66-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKYLLGIGL ILALIACKQN VSSLDEKNSV SVDLPGEMKV LVSKEKNKDG
60 70 80 90 100
KYDLIATVDK LELKGTSDKN NGSGVLEGVK ADKSKVKLTI SDDLGQTTLE
110 120 130 140 150
VFKEDGKTLV SKKVTSKDKS STEEKFNEKG EVSEKIITRA DGTRLEYTGI
160 170 180 190 200
KSDGSGKAKE VLKGYVLEGT LTAEKTTLVV KEGTVTLSKN ISKSGEVSVE
210 220 230 240 250
LNDTDSSAAT KKTAAWNSGT STLTITVNSK KTKDLVFTKE NTITVQQYDS
260 270
NGTKLEGSAV EITKLDEIKN ALK
Length:273
Mass (Da):29,367
Last modified:April 5, 2011 - v1
Checksum:iB53FC01D92F6D431
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti35P → S in strain: CA7. 1
Natural varianti39K → N in strain: PBre and 21343WI. 1
Natural varianti59D → H in strain: 42373NY3. 1
Natural varianti90I → V in strain: CA8. 1
Natural varianti114V → A in strain: PBre. 1
Natural varianti127N → S in strain: CA8. 1
Natural varianti132 – 133VS → LP in strain: CA8. 2
Natural varianti144R → K in strain: 21343WI. 1
Natural varianti149G → E in strain: PBre and 42373NY3. 1
Natural varianti164G → S in strain: PBre. 1
Natural varianti196E → A in strain: CA8 and 21343WI. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14407 Genomic DNA. Translation: CAA32579.1.
X85739 Genomic DNA. Translation: CAA59742.1.
X80182 Genomic DNA. Translation: CAA56467.1.
X69606 Genomic DNA. Translation: CAA49314.1.
AE000790 Genomic DNA. Translation: AAC66260.1.
L23136 Genomic DNA. Translation: AAA22951.1.
L23137 Genomic DNA. Translation: AAA22953.1.
L23138 Genomic DNA. Translation: AAA20947.1.
L23139 Genomic DNA. Translation: AAA20949.1.
L23140 Genomic DNA. Translation: AAA20951.1.
L23141 Genomic DNA. Translation: AAA20953.1.
L23142 Genomic DNA. Translation: AAA20955.1.
L23143 Genomic DNA. Translation: AAA20957.1.
L23144 Genomic DNA. Translation: AAA20959.1.
PIRiF49209.
G70208.
I40265.
S71529.
RefSeqiNP_045688.1. NC_001857.2.
WP_010890378.1. NC_001857.2.

Genome annotation databases

EnsemblBacteriaiAAC66260; AAC66260; BB_A15.
GeneIDi1194357.
KEGGibbu:BB_A15.
PATRICi20558954. VBIBorBur75917_1532.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14407 Genomic DNA. Translation: CAA32579.1.
X85739 Genomic DNA. Translation: CAA59742.1.
X80182 Genomic DNA. Translation: CAA56467.1.
X69606 Genomic DNA. Translation: CAA49314.1.
AE000790 Genomic DNA. Translation: AAC66260.1.
L23136 Genomic DNA. Translation: AAA22951.1.
L23137 Genomic DNA. Translation: AAA22953.1.
L23138 Genomic DNA. Translation: AAA20947.1.
L23139 Genomic DNA. Translation: AAA20949.1.
L23140 Genomic DNA. Translation: AAA20951.1.
L23141 Genomic DNA. Translation: AAA20953.1.
L23142 Genomic DNA. Translation: AAA20955.1.
L23143 Genomic DNA. Translation: AAA20957.1.
L23144 Genomic DNA. Translation: AAA20959.1.
PIRiF49209.
G70208.
I40265.
S71529.
RefSeqiNP_045688.1. NC_001857.2.
WP_010890378.1. NC_001857.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FJ1X-ray2.68E/F18-273[»]
1OSPX-ray1.95O18-273[»]
2AF5X-ray2.50A27-273[»]
2FKGX-ray2.40A27-273[»]
2FKJX-ray3.10A/B/C27-273[»]
2G8CX-ray1.15O27-273[»]
2HKDX-ray1.60A27-130[»]
A118-273[»]
2I5VX-ray1.10O27-273[»]
2I5ZX-ray1.20O27-273[»]
2OL6X-ray1.60O27-273[»]
2OL7X-ray1.35A/B27-273[»]
2OL8X-ray1.90O27-273[»]
2OY1X-ray1.86O27-273[»]
2OY5X-ray1.80O27-273[»]
2OY7X-ray1.55A27-130[»]
A119-273[»]
2OY8X-ray2.00A27-273[»]
2OYBX-ray1.30O27-273[»]
2PI3X-ray1.40O27-273[»]
3AUMX-ray1.60O27-273[»]
SMRiP0CL66.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP0CL66.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC66260; AAC66260; BB_A15.
GeneIDi1194357.
KEGGibbu:BB_A15.
PATRICi20558954. VBIBorBur75917_1532.

Phylogenomic databases

OMAiALIACKQ.

Miscellaneous databases

EvolutionaryTraceiP0CL66.

Family and domain databases

Gene3Di3.90.930.1. 1 hit.
InterProiIPR001809. OM_lipoprot_Borrelia.
IPR023322. OM_lipoprot_dom.
[Graphical view]
PfamiPF00820. Lipoprotein_1. 1 hit.
[Graphical view]
PRINTSiPR00968. OUTRSURFACE.
ProDomiPD001127. OM_lipoprot_Borrelia. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF51087. SSF51087. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOSPA_BORBU
AccessioniPrimary (citable) accession number: P0CL66
Secondary accession number(s): P0C926
, P14013, Q44882, Q44964, Q44967, Q44969, Q44971, Q57123, Q57272
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 2, 2016
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Plasmid, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.