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Protein

Protein BptA

Gene

bptA

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Virulence-associated protein essential for survival of the bacterium within the tick host and therefore within the natural life cycle of the Lyme disease spirochete.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Virulence

Enzyme and pathway databases

BioCyciBBUR224326:G9SO-1513-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BptA
Alternative name(s):
Borrelial persistence in ticks protein A
Gene namesi
Name:bptA
Ordered Locus Names:BB_E16
Encoded oniPlasmid lp250 Publication
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000001807 Componenti: Plasmid lp25

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 206187Protein BptAPRO_0000238481Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the BptA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

OMAiNEDREYK.

Family and domain databases

InterProiIPR031471. BptA.
[Graphical view]
PfamiPF17044. BPTA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0CL63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKILFFGLL LICIFLGFFF YKQKENNVIY NKIVEKFDDN VFVDETYTYL
60 70 80 90 100
FKDSNLKELV FIKSQLIIPE LKHKKMIKAT GYRADAYKAL STVYRFDFKV
110 120 130 140 150
HDNKILGFKS VIFEGFEDAK VSKHENNLPS EKWQQLKDFN IGDPNINEKF
160 170 180 190 200
FHLEFPFVVK NTLCVTISKG FFKKIKKLKR LKIMLISNED REYKIDIENF

LPKYNL
Length:206
Mass (Da):24,534
Last modified:April 5, 2011 - v1
Checksum:i25730555C70AE725
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti28 – 281V → I in strain: 297.
Natural varianti72 – 721K → E in strain: 297.
Natural varianti75 – 795KMIKA → EMMKS in strain: 297.
Natural varianti184 – 1841M → I in strain: 297.
Natural varianti206 – 2061L → F in strain: 297.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY894344 Genomic DNA. Translation: AAX69071.1.
AE000785 Genomic DNA. Translation: AAC66050.1.
PIRiC70226.
RefSeqiNP_045423.1. NC_001850.1.
WP_010890264.1. NC_001850.1.

Genome annotation databases

EnsemblBacteriaiAAC66050; AAC66050; BB_E16.
KEGGibbu:BB_E16.
PATRICi20558437. VBIBorBur75917_1277.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY894344 Genomic DNA. Translation: AAX69071.1.
AE000785 Genomic DNA. Translation: AAC66050.1.
PIRiC70226.
RefSeqiNP_045423.1. NC_001850.1.
WP_010890264.1. NC_001850.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC66050; AAC66050; BB_E16.
KEGGibbu:BB_E16.
PATRICi20558437. VBIBorBur75917_1277.

Phylogenomic databases

OMAiNEDREYK.

Enzyme and pathway databases

BioCyciBBUR224326:G9SO-1513-MONOMER.

Family and domain databases

InterProiIPR031471. BptA.
[Graphical view]
PfamiPF17044. BPTA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBPTA_BORBU
AccessioniPrimary (citable) accession number: P0CL63
Secondary accession number(s): O50712, Q56NH3, Q56NH4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 7, 2016
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.