Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P0CL51

- SYR_SALTY

UniProt

P0CL51 - SYR_SALTY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Arginine--tRNA ligase

Gene

argS

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSENT99287:GCTI-1921-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:STM1909
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 577577Arginine--tRNA ligasePRO_0000151602Add
BLAST

Proteomic databases

PRIDEiP0CL51.

Interactioni

Subunit structurei

Monomer.By similarity

Structurei

Secondary structure

1
577
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi4 – 1916
Helixi24 – 307
Helixi37 – 393
Beta strandi41 – 455
Helixi46 – 494
Helixi56 – 6611
Turni70 – 723
Beta strandi73 – 797
Beta strandi82 – 876
Helixi89 – 957
Beta strandi96 – 983
Beta strandi110 – 1123
Beta strandi114 – 1185
Helixi132 – 14817
Beta strandi152 – 1565
Helixi165 – 1684
Helixi173 – 1764
Helixi178 – 19518
Beta strandi197 – 2004
Turni202 – 2043
Helixi206 – 2149
Beta strandi217 – 2193
Helixi224 – 24522
Helixi264 – 27512
Beta strandi278 – 2814
Beta strandi284 – 2874
Helixi289 – 2913
Beta strandi302 – 3054
Helixi313 – 32816
Beta strandi331 – 3355
Helixi339 – 3413
Helixi342 – 35413
Beta strandi359 – 3635
Helixi364 – 3674
Beta strandi368 – 3703
Beta strandi376 – 3783
Beta strandi382 – 3865
Helixi390 – 40718
Turni409 – 4113
Helixi417 – 43418
Beta strandi438 – 4403
Helixi446 – 4505
Beta strandi452 – 4554
Helixi457 – 47115
Helixi476 – 4827
Helixi487 – 4893
Helixi493 – 51422
Helixi519 – 53618
Helixi546 – 57025

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1LLEmodel-A1-577[»]
ProteinModelPortaliP0CL51.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi122 – 13211"HIGH" regionAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000247212.
KOiK01887.
OMAiMEHMGFG.
OrthoDBiEOG6JB13C.
PhylomeDBiP0CL51.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0CL51-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNIQALLSEK VSQAMIAAGA PADCEPQVRQ SAKVQFGDYQ ANGMMAVAKK
60 70 80 90 100
LGMAPRQLAE QVLTHLDLSG IASKVEIAGP GFINIFLEPA FLAEQVQQAL
110 120 130 140 150
ASDRLGVSQP TRQTIVVDYS APNVAKEMHV GHLRSTIIGD AAVRTLEFLG
160 170 180 190 200
HHVIRANHVG DWGTQFGMLI AWLEKQQQEN AGDMALADLE GFYRDAKKHY
210 220 230 240 250
DEDEAFAERA RNYVVKLQSG DTYFREMWRK LVDITMTQNQ ITYDRLNVTL
260 270 280 290 300
TRDDVMGESL YNPMLPGIVA DLKAKGLAVE SEGATVVFLD EFKNKEGDPM
310 320 330 340 350
GVIIQKKDGG YLYTTTDIAC AKYRYETLHA DRVLYYIDSR QHQHLMQAWT
360 370 380 390 400
IVRKAGYVPD SVPLEHHMFG MMLGKDGKPF KTRAGGTVKL ADLLDEALER
410 420 430 440 450
ARRLVAEKNP DMPADELEKL ANAVGIGAVK YADLSKNRTT DYIFDWDNML
460 470 480 490 500
AFEGNTAPYM QYAYTRVLSV FRKANIDEQA LASAPVIISE DREAQLAARL
510 520 530 540 550
LQFEETLTVV AREGTPHVMC AYLYDVAGLF SGFYEHCPIL SAENDAVRNS
560 570
RLKLAQLTAK TLKLGLDTLG IETVERM
Length:577
Mass (Da):64,275
Last modified:March 8, 2011 - v1
Checksum:i842D46DD38EB44B7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006468 Genomic DNA. Translation: AAL20825.1.
RefSeqiNP_460866.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL20825; AAL20825; STM1909.
GeneIDi1253430.
KEGGistm:STM1909.
PATRICi32382373. VBISalEnt20916_2025.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006468 Genomic DNA. Translation: AAL20825.1 .
RefSeqi NP_460866.1. NC_003197.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1LLE model - A 1-577 [» ]
ProteinModelPortali P0CL51.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P0CL51.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL20825 ; AAL20825 ; STM1909 .
GeneIDi 1253430.
KEGGi stm:STM1909.
PATRICi 32382373. VBISalEnt20916_2025.

Phylogenomic databases

HOGENOMi HOG000247212.
KOi K01887.
OMAi MEHMGFG.
OrthoDBi EOG6JB13C.
PhylomeDBi P0CL51.

Enzyme and pathway databases

BioCyci SENT99287:GCTI-1921-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiSYR_SALTY
AccessioniPrimary (citable) accession number: P0CL51
Secondary accession number(s): P74871
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: March 8, 2011
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3