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Protein

Transcriptional regulator hilD

Gene

hilD

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi225 – 24319H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSENT99287:GCTI-2892-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulator hilD
Gene namesi
Name:hilD
Ordered Locus Names:STM2875
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309Transcriptional regulator hilDPRO_0000194524Add
BLAST

Proteomic databases

PaxDbiP0CL08.
PRIDEiP0CL08.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM2875.

Structurei

3D structure databases

ProteinModelPortaliP0CL08.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4107EHP. Bacteria.
ENOG41122VW. LUCA.
HOGENOMiHOG000028238.
OMAiQSCIENE.
OrthoDBiEOG63C0R5.
PhylomeDBiP0CL08.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0CL08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENVTFVSNS HQRPAADNLQ KLKSLLTNTR QQIKSQTQQV TIKNLYVSSF
60 70 80 90 100
TLVCFRSGKL TISNNHDTIY CDEPGMLVLK KEQVVNVTLE EVNGHMDFDI
110 120 130 140 150
LEIPTQRLGA LYALIPNEQQ TKMAVPTEKA QKIFYTPDFP ARREVFEHLK
160 170 180 190 200
TAFSCTKDTS KGCSNCNNKS CIENEELIPY FLLFLLTAFL RLPESYEIIL
210 220 230 240 250
SSAQITLKER VYNIISSSPS RQWKLTDVAD HIFMSTSTLK RKLAEEGTSF
260 270 280 290 300
SDIYLSARMN QAAKLLRIGN HNVNAVALKC GYDSTSYFIQ CFKKYFKTTP

STFIKMANH
Length:309
Mass (Da):35,218
Last modified:March 8, 2011 - v1
Checksum:iB827FC4B3785358E
GO

Sequence cautioni

The sequence AAB60187.1 differs from that shown. Reason: Frameshift at positions 115, 181 and 206. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti182 – 1832Missing in AAB60187 (PubMed:7476203).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL21755.1.
U21676 Genomic DNA. Translation: AAB60187.1. Frameshift.
PIRiS69787.
RefSeqiNP_461796.1. NC_003197.1.
WP_000432699.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL21755; AAL21755; STM2875.
GeneIDi1254398.
KEGGistm:STM2875.
PATRICi32384438. VBISalEnt20916_3031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL21755.1.
U21676 Genomic DNA. Translation: AAB60187.1. Frameshift.
PIRiS69787.
RefSeqiNP_461796.1. NC_003197.1.
WP_000432699.1. NC_003197.1.

3D structure databases

ProteinModelPortaliP0CL08.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM2875.

Proteomic databases

PaxDbiP0CL08.
PRIDEiP0CL08.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL21755; AAL21755; STM2875.
GeneIDi1254398.
KEGGistm:STM2875.
PATRICi32384438. VBISalEnt20916_3031.

Phylogenomic databases

eggNOGiENOG4107EHP. Bacteria.
ENOG41122VW. LUCA.
HOGENOMiHOG000028238.
OMAiQSCIENE.
OrthoDBiEOG63C0R5.
PhylomeDBiP0CL08.

Enzyme and pathway databases

BioCyciSENT99287:GCTI-2892-MONOMER.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.
  2. "PhoP/PhoQ transcriptional repression of Salmonella typhimurium invasion genes: evidence for a role in protein secretion."
    Pegues D.A., Hantman M.J., Behlau I., Miller S.I.
    Mol. Microbiol. 17:169-181(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-225.
    Strain: ATCC 14028s / SGSG 2262.

Entry informationi

Entry nameiHILD_SALTY
AccessioniPrimary (citable) accession number: P0CL08
Secondary accession number(s): P41782, Q9X5C3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: March 8, 2011
Last modified: February 17, 2016
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.