Skip Header

Contribute Send feedback
Read comments (?) or add your own

P0CJ83 (FTN_BACFR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferritin
EC=1.16.3.1
Gene names
Name:ftnA
Ordered Locus Names:BF3048
OrganismBacteroides fragilis (strain YCH46) [Complete proteome] [HAMAP]
Taxonomic identifier295405 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides ›

Protein attributes

Sequence length159 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May alleviate iron toxicity in the presence of oxygen.

Catalytic activity

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.

Subunit structure

Homooligomer of 24 subunits that assemble into a spherical protein shell (12 +/- 1 nM diameter) that can sequester at least 2000 iron atoms By similarity. Ref.2

Sequence similarities

Belongs to the ferritin family. Prokaryotic subfamily.

Contains 1 ferritin-like diiron domain.

Ontologies

Keywords
   Biological processIron storage
   LigandIron
Metal-binding
   Molecular functionOxidoreductase
   Technical termComplete proteome
Direct protein sequencing
Gene Ontology (GO)
   Biological_processcellular iron ion homeostasis

Inferred from electronic annotation. Source: UniProtKB-KW

iron ion transport

Inferred from electronic annotation. Source: InterPro

   Molecular_functionferric iron binding

Inferred from electronic annotation. Source: InterPro

ferroxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 159159Ferritin
PRO_0000201098

Regions

Domain1 – 145145Ferritin-like diiron

Sites

Metal binding171Iron 1 By similarity
Metal binding501Iron 1 By similarity
Metal binding501Iron 2 By similarity
Metal binding531Iron 1 By similarity
Metal binding941Iron 2 By similarity
Metal binding1271Iron 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
P0CJ83 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 3CAD5FC4984A0AB9

FASTA15918,064
        10         20         30         40         50         60 
MISEKLQNAI NEQISAEMWS SNLYLSMSFY FEREGFSGFA HWMKKQSQEE MGHAYAMADY 

        70         80         90        100        110        120 
IIKRGGIAKV DKIDVVPTGW GTPLEVFEHV FEHERHVSKL VDALVDIAAA EKDKATQDFL 

       130        140        150 
WGFVREQVEE EATAQGIVDK IKRAGDAGIF FIDSQLGQR

« Hide

References

« Hide 'large scale' references
[1]"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation."
Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y.
Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YCH46.
[2]"Isolation of a ferritin from Bacteroides fragilis."
Rocha E.R., Andrews S.C., Keen J.N., Brock J.H.
FEMS Microbiol. Lett. 74:207-212(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-30, COFACTOR, SUBUNIT.
Strain: 20656-2-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006841 Genomic DNA. Translation: BAD49794.1.
RefSeqYP_100328.1. NC_006347.1.

3D structure databases

ProteinModelPortalP0CJ83.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD49794; BAD49794; BF3048.
GeneID3083244.
KEGGbfr:BF3048.
PATRIC21051650. VBIBacFra17906_2916.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000223382.
KOK02217.
OMAKEEMGHA.

Family and domain databases

Gene3D1.20.1260.10. 1 hit.
InterProIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERPTHR11431. PTHR11431. 1 hit.
PfamPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
PROSITEPS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFTN_BACFR
AccessionPrimary (citable) accession number: P0CJ83
Secondary accession number(s): P28733, Q9AEU4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: February 8, 2011
Last modified: May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents