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P0CJ81 (P65_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proline-rich P65 protein
Gene names
Name:p65
Ordered Locus Names:MPN_309
ORF Names:MP527
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Subcellular location

Cell membrane; Peripheral membrane protein. Note: Probably with epitopes exposed at the cell surface. Ref.1 Ref.4

Domain

The penta/hexapeptides repeats form a proline-rich acidic domain. In addition, a part of this region contains a perfect direct repeat.

Post-translational modification

The N-terminus is blocked Probable.

Caution

The protein sequence for 83-95 (Ref.4) might be that for residues 148-160; the 2 sequences are identical.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainRepeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Proline-rich P65 protein
PRO_0000058145

Regions

Repeat40 – 4561
Repeat75 – 8062
Repeat83 – 8753
Repeat89 – 9354
Repeat95 – 9955
Repeat101 – 10556
Repeat107 – 11157
Repeat119 – 12358
Repeat140 – 14569
Repeat148 – 152510
Repeat154 – 158511
Repeat168 – 172512
Region40 – 17213312 X 5 AA repeats of D-P-N-Q-A-Y

Sequences

Sequence LengthMass (Da)Tools
P0CJ81 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 4805F2DAD0588232

FASTA40547,040
        10         20         30         40         50         60 
MDINKPGWNQ SDQQATAYDP NQQQYYGDGS TYYDPDQAVD PNQAYYPDPN TYPDAAAYYG 

        70         80         90        100        110        120 
YGQDGQAYPQ DYAQDPNQAY YADPNAYQDP NAYTDPNAYV DPNAYQDPNA YVDPNNYTDP 

       130        140        150        160        170        180 
NAYYGYGQDG QAYPQDYAQD PNQAYYADPN AYQDPNAYTD PYYVTSTDPN AYYGQVDNVP 

       190        200        210        220        230        240 
ALEASDLAYE VTPQEQAAEQ ELFSEPETKV IREIHEFPFE KIRSYFQTDF DSYNSRLTQL 

       250        260        270        280        290        300 
KDKLDNAIFS MRKAIDTVKE NSANLQIMKQ NFERQLKEQQ TQRLTSNTDA EKIGAKINQL 

       310        320        330        340        350        360 
EERMQRLSRT MESVEWTKKE PRQEQFDPRF VDPRNFNNYV NNTDTMMSMF EKVLMMNLLR 

       370        380        390        400 
STTPVQPPVQ YFTPQPLTAS PRPVYEEPIS ASFRRRGYRG DEFYE 

« Hide

References

« Hide 'large scale' references
[1]"The proline-rich P65 protein of Mycoplasma pneumoniae is a component of the Triton X-100-insoluble fraction and exhibits size polymorphism in the strains M129 and FH."
Proft T., Hilbert H., Layh-Schmitt G., Herrmann R.
J. Bacteriol. 177:3370-3378(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION.
Strain: ATCC 29342 / M129.
[2]"Transposon mutagenesis reinforces the correlation between Mycoplasma pneumoniae cytoskeletal protein HMW2 and cytadherence."
Krause D.C., Proft T., Hedreyda C.T., Hilbert H., Plagens H., Herrmann R.
J. Bacteriol. 179:2668-2677(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 29342 / M129.
[3]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.
[4]"Identification and characterization of hitherto unknown Mycoplasma pneumoniae proteins."
Proft T., Herrmann R.
Mol. Microbiol. 13:337-348(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 40-75 AND 83-95, SUBCELLULAR LOCATION.
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z34977 Genomic DNA. Translation: CAA84429.1.
U59896 Genomic DNA. Translation: AAB52526.1.
U00089 Genomic DNA. Translation: AAB96175.1.
Z32653 Genomic DNA. Translation: CAA83574.1.
Z32655 Genomic DNA. Translation: CAA83576.1.
PIRS73853.
RefSeqNP_109997.1. NC_000912.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96175; AAB96175; MPN_309.
GeneID876932.
KEGGmpn:MPN309.
PATRIC20021970. VBIMycPne110_0333.

Phylogenomic databases

OrthoDBEOG6DNTDK.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-325-MONOMER.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameP65_MYCPN
AccessionPrimary (citable) accession number: P0CJ81
Secondary accession number(s): P53663 expand/collapse secondary AC list , P53664, Q6LAC2, Q6LAC3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 13, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names