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P0CH88

- SP4_BOMTE

UniProt

P0CH88 - SP4_BOMTE

Protein

Venom protease

Gene
N/A
Organism
Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. serine-type peptidase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protease, Serine protease

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Venom protease (EC:3.4.21.-)
    Alternative name(s):
    Allergen: Bom t 4
    OrganismiBombus terrestris (Buff-tailed bumblebee) (Apis terrestris)
    Taxonomic identifieri30195 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataApoideaApidaeBombusBombus

    Subcellular locationi

    Secreted 1 Publication

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human.1 Publication

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei156. Bom t 4.
    3160. Bom t 4.0101.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – ›20›20Venom proteasePRO_0000401925Add
    BLAST

    Post-translational modificationi

    Contains 3 disulfide bonds.By similarity
    N-glycosylated.By similarity

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Expressioni

    Tissue specificityi

    Expressed by the venom duct.1 Publication

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S1 family.Curated
    Contains 1 peptidase S1 domain.Curated

    Family and domain databases

    InterProiIPR009003. Trypsin-like_Pept_dom.
    [Graphical view]
    SUPFAMiSSF50494. SSF50494. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    P0CH88-1 [UniParc]FASTAAdd to Basket

    « Hide

    VVGGKPAKLG AWPWMVALGF                                    20
    Length:20
    Mass (Da):2,085
    Last modified:November 30, 2010 - v1
    Checksum:iB3ECC6677611C32F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei20 – 201

    Cross-referencesi

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 156. Bom t 4.
    3160. Bom t 4.0101.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR009003. Trypsin-like_Pept_dom.
    [Graphical view ]
    SUPFAMi SSF50494. SSF50494. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Occupational allergy to bumblebees: allergens of Bombus terrestris."
      Hoffman D.R., El-Choufani S.E., Smith M.M., de Groot H.
      J. Allergy Clin. Immunol. 108:855-860(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, ALLERGEN.
      Tissue: Venom.

    Entry informationi

    Entry nameiSP4_BOMTE
    AccessioniPrimary (citable) accession number: P0CH88
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 30, 2010
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 9 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. Peptidase families
      Classification of peptidase families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3