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P0CH88 (SP4_BOMTE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Venom protease

EC=3.4.21.-
Alternative name(s):
Allergen=Bom t 4
OrganismBombus terrestris (Buff-tailed bumblebee) (Apis terrestris)
Taxonomic identifier30195 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataApoideaApidaeBombusBombus

Protein attributes

Sequence length20 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secreted Ref.1.

Tissue specificity

Expressed by the venom duct. Ref.1

Post-translational modification

Contains 3 disulfide bonds By similarity.

N-glycosylated By similarity.

Allergenic properties

Causes an allergic reaction in human. Ref.1

Sequence similarities

Belongs to the peptidase S1 family.

Contains 1 peptidase S1 domain.

Ontologies

Keywords
   Cellular componentSecreted
   DiseaseAllergen
   Molecular functionHydrolase
Protease
Serine protease
   PTMDisulfide bond
Glycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionserine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›20›20Venom protease
PRO_0000401925

Experimental info

Non-terminal residue201

Sequences

Sequence LengthMass (Da)Tools
P0CH88 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: B3ECC6677611C32F

FASTA202,085
        10         20 
VVGGKPAKLG AWPWMVALGF 

« Hide

References

[1]"Occupational allergy to bumblebees: allergens of Bombus terrestris."
Hoffman D.R., El-Choufani S.E., Smith M.M., de Groot H.
J. Allergy Clin. Immunol. 108:855-860(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, ALLERGEN.
Tissue: Venom.

Cross-references

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome156. Bom t 4.
3160. Bom t 4.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR009003. Trypsin-like_Pept_dom.
[Graphical view]
SUPFAMSSF50494. SSF50494. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSP4_BOMTE
AccessionPrimary (citable) accession number: P0CH88
Entry history
Integrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: November 30, 2010
Last modified: May 14, 2014
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries

Allergens

Nomenclature of allergens and list of entries