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Venom protease

Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris)
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli


GO - Molecular functioni


Molecular functionHydrolase, Protease, Serine protease

Names & Taxonomyi

Protein namesi
Recommended name:
Venom protease (EC:3.4.21.-)
Alternative name(s):
Allergen: Bom t 4
OrganismiBombus terrestris (Buff-tailed bumblebee) (Apis terrestris)
Taxonomic identifieri30195 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataApoideaApidaeBombusBombus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti


Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.1 Publication

Keywords - Diseasei


Protein family/group databases

Allergomei156. Bom t 4.
3160. Bom t 4.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004019251 – ›20Venom proteaseAdd BLAST›20

Post-translational modificationi

Contains 3 disulfide bonds.By similarity
N-glycosylated.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein


Tissue specificityi

Expressed by the venom duct.1 Publication

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S1 family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
SUPFAMiSSF50494. SSF50494. 1 hit.


Sequence statusi: Fragment.

P0CH88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20
Mass (Da):2,085
Last modified:November 30, 2010 - v1

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei201

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiSP4_BOMTE
AccessioniPrimary (citable) accession number: P0CH88
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: November 30, 2010
Last modified: April 12, 2017
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)


Keywords - Technical termi

Direct protein sequencing


  1. Allergens
    Nomenclature of allergens and list of entries
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families