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P0CH63

- DDI2_YEAST

UniProt

P0CH63 - DDI2_YEAST

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Protein
DNA damage-inducible protein 2
Gene
DDI2, YFL061W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. cyanamide hydratase activity Source: UniProtKB
  2. phosphoric diester hydrolase activity Source: InterPro
  3. zinc ion binding Source: UniProtKB

GO - Biological processi

  1. cellular response to DNA damage stimulus Source: UniProtKB
  2. cyanamide metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciYEAST:G3O-30406-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA damage-inducible protein 2
Gene namesi
Name:DDI2
Ordered Locus Names:YFL061W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VI

Organism-specific databases

SGDiS000001833. DDI2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 225225DNA damage-inducible protein 2
PRO_0000202670Add
BLAST

Expressioni

Inductioni

By DNA damage.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi35506. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliP0CH63.

Family & Domainsi

Phylogenomic databases

OrthoDBiEOG7CRV1M.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
InterProiIPR017771. Cyanamide_hydratase_HD.
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
[Graphical view]
PfamiPF01966. HD. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03401. cyanamide_fam. 1 hit.

Sequencei

Sequence statusi: Complete.

P0CH63-1 [UniParc]FASTAAdd to Basket

« Hide

MSQYGFVRVP REVEKAIPVV NAPRPRAVVP PPNSETARLV REYAAKELTA    50
PVLNHSLRVF QYSVAIIRDQ FPAWDLDQEV LYVTCLLHDI ATTDKNMRAT 100
KMSFEYYGGI LSRELVFNAT GGNQDYADAV TEAIIRHQDL TGTGYITTLG 150
LILQIATTLD NVGSNTDLIH IDTVSAINEQ FPRLHWLSCF ATVVDTENSR 200
KPWGHTSSLG DDFSKKVICN TFGYN 225
Length:225
Mass (Da):25,152
Last modified:October 5, 2010 - v1
Checksum:iF4890BF675E652B2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D50617 Genomic DNA. Translation: BAA09180.1.
AY692638 Genomic DNA. Translation: AAT92657.1.
BK006940 Genomic DNA. Translation: DAA12379.1.
PIRiS56194.
RefSeqiNP_014064.1. NM_001183173.1.
NP_116594.1. NM_001179906.1.

Genome annotation databases

EnsemblFungiiYFL061W; YFL061W; YFL061W.
YNL335W; YNL335W; YNL335W.
GeneIDi850483.
855381.
KEGGisce:YFL061W.
sce:YNL335W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D50617 Genomic DNA. Translation: BAA09180.1 .
AY692638 Genomic DNA. Translation: AAT92657.1 .
BK006940 Genomic DNA. Translation: DAA12379.1 .
PIRi S56194.
RefSeqi NP_014064.1. NM_001183173.1.
NP_116594.1. NM_001179906.1.

3D structure databases

ProteinModelPortali P0CH63.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35506. 2 interactions.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YFL061W ; YFL061W ; YFL061W .
YNL335W ; YNL335W ; YNL335W .
GeneIDi 850483.
855381.
KEGGi sce:YFL061W.
sce:YNL335W.

Organism-specific databases

SGDi S000001833. DDI2.

Phylogenomic databases

OrthoDBi EOG7CRV1M.

Enzyme and pathway databases

BioCyci YEAST:G3O-30406-MONOMER.

Miscellaneous databases

NextBioi 966143.

Family and domain databases

Gene3Di 1.10.3210.10. 1 hit.
InterProi IPR017771. Cyanamide_hydratase_HD.
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
[Graphical view ]
Pfami PF01966. HD. 1 hit.
[Graphical view ]
SMARTi SM00471. HDc. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03401. cyanamide_fam. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp."
    Fu Y., Zhu Y., Zhang K., Yeung M., Durocher D., Xiao W.
    Cell 133:601-611(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.

Entry informationi

Entry nameiDDI2_YEAST
AccessioniPrimary (citable) accession number: P0CH63
Secondary accession number(s): D6VTG9, P43543
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: October 5, 2010
Last modified: May 14, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

External Data

Dasty 3

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