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P0CH63

- DDI2_YEAST

UniProt

P0CH63 - DDI2_YEAST

Protein

DNA damage-inducible protein 2

Gene

DDI2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (05 Oct 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. cyanamide hydratase activity Source: UniProtKB
    2. phosphoric diester hydrolase activity Source: InterPro
    3. zinc ion binding Source: UniProtKB

    GO - Biological processi

    1. cellular response to DNA damage stimulus Source: UniProtKB
    2. cyanamide metabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Lyase

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30406-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA damage-inducible protein 2
    Gene namesi
    Name:DDI2
    Ordered Locus Names:YFL061W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VI

    Organism-specific databases

    SGDiS000001833. DDI2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 225225DNA damage-inducible protein 2PRO_0000202670Add
    BLAST

    Expressioni

    Inductioni

    By DNA damage.1 Publication

    Interactioni

    Protein-protein interaction databases

    BioGridi35506. 2 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliP0CH63.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    OrthoDBiEOG7CRV1M.

    Family and domain databases

    Gene3Di1.10.3210.10. 1 hit.
    InterProiIPR017771. Cyanamide_hydratase_HD.
    IPR003607. HD/PDEase_dom.
    IPR006674. HD_domain.
    [Graphical view]
    PfamiPF01966. HD. 1 hit.
    [Graphical view]
    SMARTiSM00471. HDc. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03401. cyanamide_fam. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0CH63-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQYGFVRVP REVEKAIPVV NAPRPRAVVP PPNSETARLV REYAAKELTA    50
    PVLNHSLRVF QYSVAIIRDQ FPAWDLDQEV LYVTCLLHDI ATTDKNMRAT 100
    KMSFEYYGGI LSRELVFNAT GGNQDYADAV TEAIIRHQDL TGTGYITTLG 150
    LILQIATTLD NVGSNTDLIH IDTVSAINEQ FPRLHWLSCF ATVVDTENSR 200
    KPWGHTSSLG DDFSKKVICN TFGYN 225
    Length:225
    Mass (Da):25,152
    Last modified:October 5, 2010 - v1
    Checksum:iF4890BF675E652B2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D50617 Genomic DNA. Translation: BAA09180.1.
    AY692638 Genomic DNA. Translation: AAT92657.1.
    BK006940 Genomic DNA. Translation: DAA12379.1.
    PIRiS56194.
    RefSeqiNP_014064.1. NM_001183173.1.
    NP_116594.1. NM_001179906.1.

    Genome annotation databases

    EnsemblFungiiYFL061W; YFL061W; YFL061W.
    YNL335W; YNL335W; YNL335W.
    GeneIDi850483.
    855381.
    KEGGisce:YFL061W.
    sce:YNL335W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D50617 Genomic DNA. Translation: BAA09180.1 .
    AY692638 Genomic DNA. Translation: AAT92657.1 .
    BK006940 Genomic DNA. Translation: DAA12379.1 .
    PIRi S56194.
    RefSeqi NP_014064.1. NM_001183173.1.
    NP_116594.1. NM_001179906.1.

    3D structure databases

    ProteinModelPortali P0CH63.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35506. 2 interactions.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YFL061W ; YFL061W ; YFL061W .
    YNL335W ; YNL335W ; YNL335W .
    GeneIDi 850483.
    855381.
    KEGGi sce:YFL061W.
    sce:YNL335W.

    Organism-specific databases

    SGDi S000001833. DDI2.

    Phylogenomic databases

    OrthoDBi EOG7CRV1M.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30406-MONOMER.

    Miscellaneous databases

    NextBioi 966143.

    Family and domain databases

    Gene3Di 1.10.3210.10. 1 hit.
    InterProi IPR017771. Cyanamide_hydratase_HD.
    IPR003607. HD/PDEase_dom.
    IPR006674. HD_domain.
    [Graphical view ]
    Pfami PF01966. HD. 1 hit.
    [Graphical view ]
    SMARTi SM00471. HDc. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03401. cyanamide_fam. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. "Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp."
      Fu Y., Zhu Y., Zhang K., Yeung M., Durocher D., Xiao W.
      Cell 133:601-611(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION.

    Entry informationi

    Entry nameiDDI2_YEAST
    AccessioniPrimary (citable) accession number: P0CH63
    Secondary accession number(s): D6VTG9, P43543
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 5, 2010
    Last sequence update: October 5, 2010
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome VI
      Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

    External Data

    Dasty 3