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Protein

DNA damage-inducible protein 2

Gene

DDI2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciYEAST:G3O-30406-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA damage-inducible protein 2
Gene namesi
Name:DDI2
Ordered Locus Names:YFL061W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome VI

Organism-specific databases

SGDiS000001833. DDI2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 225225DNA damage-inducible protein 2PRO_0000202670Add
BLAST

Expressioni

Inductioni

By DNA damage.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi35506. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliP0CH63.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

InParanoidiP0CH63.
OrthoDBiEOG7CRV1M.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
InterProiIPR017771. Cyanamide_hydratase_HD.
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
[Graphical view]
PfamiPF01966. HD. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03401. cyanamide_fam. 1 hit.

Sequencei

Sequence statusi: Complete.

P0CH63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQYGFVRVP REVEKAIPVV NAPRPRAVVP PPNSETARLV REYAAKELTA
60 70 80 90 100
PVLNHSLRVF QYSVAIIRDQ FPAWDLDQEV LYVTCLLHDI ATTDKNMRAT
110 120 130 140 150
KMSFEYYGGI LSRELVFNAT GGNQDYADAV TEAIIRHQDL TGTGYITTLG
160 170 180 190 200
LILQIATTLD NVGSNTDLIH IDTVSAINEQ FPRLHWLSCF ATVVDTENSR
210 220
KPWGHTSSLG DDFSKKVICN TFGYN
Length:225
Mass (Da):25,152
Last modified:October 5, 2010 - v1
Checksum:iF4890BF675E652B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA. Translation: BAA09180.1.
AY692638 Genomic DNA. Translation: AAT92657.1.
BK006940 Genomic DNA. Translation: DAA12379.1.
PIRiS56194.
RefSeqiNP_014064.1. NM_001183173.1.
NP_116594.1. NM_001179906.1.

Genome annotation databases

EnsemblFungiiYFL061W; YFL061W; YFL061W.
YNL335W; YNL335W; YNL335W.
GeneIDi850483.
855381.
KEGGisce:YFL061W.
sce:YNL335W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA. Translation: BAA09180.1.
AY692638 Genomic DNA. Translation: AAT92657.1.
BK006940 Genomic DNA. Translation: DAA12379.1.
PIRiS56194.
RefSeqiNP_014064.1. NM_001183173.1.
NP_116594.1. NM_001179906.1.

3D structure databases

ProteinModelPortaliP0CH63.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35506. 2 interactions.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYFL061W; YFL061W; YFL061W.
YNL335W; YNL335W; YNL335W.
GeneIDi850483.
855381.
KEGGisce:YFL061W.
sce:YNL335W.

Organism-specific databases

SGDiS000001833. DDI2.

Phylogenomic databases

InParanoidiP0CH63.
OrthoDBiEOG7CRV1M.

Enzyme and pathway databases

BioCyciYEAST:G3O-30406-MONOMER.

Miscellaneous databases

NextBioi966143.
PROiP0CH63.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
InterProiIPR017771. Cyanamide_hydratase_HD.
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
[Graphical view]
PfamiPF01966. HD. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03401. cyanamide_fam. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp."
    Fu Y., Zhu Y., Zhang K., Yeung M., Durocher D., Xiao W.
    Cell 133:601-611(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.

Entry informationi

Entry nameiDDI2_YEAST
AccessioniPrimary (citable) accession number: P0CH63
Secondary accession number(s): D6VTG9, P43543
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: October 5, 2010
Last modified: April 29, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.