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P0CG39 (POTEJ_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
POTE ankyrin domain family member J
Gene names
Name:POTEJ
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1038 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

In the N-terminal section; belongs to the POTE family.

In the C-terminal section; belongs to the actin family.

Contains 5 ANK repeats.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10381038POTE ankyrin domain family member J
PRO_0000395414

Regions

Repeat135 – 16430ANK 1
Repeat168 – 19730ANK 2
Repeat201 – 23030ANK 3
Repeat234 – 26330ANK 4
Repeat267 – 29630ANK 5
Region666 – 1038373Actin-like
Coiled coil605 – 66157 Potential

Sequences

Sequence LengthMass (Da)Tools
P0CG39 [UniParc].

Last modified July 13, 2010. Version 1.
Checksum: FFDFF97D149A0899

FASTA1,038117,390
        10         20         30         40         50         60 
MVAEVDSMPA ASSVKKPFVL RSKMGKWCRH CFPCCRGSGK SNVGTSGDQD DSTMKTLRSK 

        70         80         90        100        110        120 
MGKWCCHCFP CCRGSGKSNV GAWGDYDDSA FVEPRYHVRR EDLDKLHRAA WWGKVARKDL 

       130        140        150        160        170        180 
IVMLRDTDVN KQDKQKRTAL HLASANGNSG VVKLLLDRRC QLNVLDNKKR TALTKAVQCQ 

       190        200        210        220        230        240 
EDECALMLLE HGTDPNIPDE YGNTTLHYAI YNEDKLMAKA LLLYGADIES KNKHGLTPLL 

       250        260        270        280        290        300 
LGVHEQKQQV VKFLIKKKAN LNALDRYGRT ALILAVCCGS ASIVSLLLEQ NIDVSSQDLS 

       310        320        330        340        350        360 
GQTAREYAVS SHHHVICQLL SDYKEKQMLK ISSENSNPEQ DLKLTSEEES QRFKGSENSQ 

       370        380        390        400        410        420 
PEKMSQEPEI NKDGDREVEE EMKKHESNNV GLLENLSNGV TAGNGDDGLI PQRKSRTPEN 

       430        440        450        460        470        480 
QQFPDNESEE YHRICELVSD YKEKQMPKYS SENSNPEQDL KLTSEEESQR LKGSENGQPE 

       490        500        510        520        530        540 
KRSQEPEINK DGDRELENFM AIEEMKKHGS THVGFPENLT NGATAGNGDD GLIPPRKSRT 

       550        560        570        580        590        600 
PESQQFPDTE NEEYHSDEQN DTQKQFCEEQ NTGILHDEIL IHEEKQIEVV EKMNSELSLS 

       610        620        630        640        650        660 
CKKERDFLHE NSMLREEIAM LRLELDTMKH QSQLRKKKYL EDIESVKKKN DNLLKALQLN 

       670        680        690        700        710        720 
ELTMDDDTAV LVIDNGSGMC KAGFAGDDAP RAVFPSIVGC PRQQGMMGGM HQKESYVGKE 

       730        740        750        760        770        780 
AQSKRGILTL KYPMEHGIIT NWDDMEKIWH HTFYNELRVA PEEHPILLTE APLNPKANRE 

       790        800        810        820        830        840 
KMTQIMFETF NTPAMYVAIQ AMLSLYTSGR TTGIVMDSGD GVTHTVPIYD GNALPHATLR 

       850        860        870        880        890        900 
LDLAGRELTD YLMKILTERG YRFTTMAERE IVRDIKEKLC YVALDFEQEM AMVASSSSLE 

       910        920        930        940        950        960 
KSYELPDGQV ITISNEWFRC PEALFQPCFL GMESCGIHET TFNSIMKSDV DIRKDLYTNT 

       970        980        990       1000       1010       1020 
VLSGGTTMYP GMAHRMQKEI AALAPSMMKI RIIAPPKRKY SVWVGGSILA SLSTFQQMWI 

      1030 
SKQEYDESGP SIVHRKCF 

« Hide

References

[1]"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. expand/collapse author list , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC140481 Genomic DNA. No translation available.
RefSeqNP_001264012.1. NM_001277083.1.
UniGeneHs.558829.

3D structure databases

ProteinModelPortalP0CG39.
SMRP0CG39. Positions 12-328, 669-1038.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid576066. 3 interactions.
IntActP0CG39. 1 interaction.

PTM databases

PhosphoSiteP0CG39.

Polymorphism databases

DMDM300681052.

Proteomic databases

PRIDEP0CG39.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000409602; ENSP00000387176; ENSG00000222038.
GeneID653781.
KEGGhsa:653781.
UCSCuc021vor.2. human.

Organism-specific databases

CTD653781.
GeneCardsGC02P131370.
HGNCHGNC:37094. POTEJ.
HPAHPA041264.
HPA042822.
HPA043260.
neXtProtNX_P0CG39.
PharmGKBPA165697368.
GenAtlasSearch...

Phylogenomic databases

HOGENOMHOG000115614.
KOK17299.
OrthoDBEOG7FBRHS.
PhylomeDBP0CG39.
TreeFamTF354237.

Enzyme and pathway databases

SignaLinkP0CG39.

Gene expression databases

BgeeP0CG39.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
InterProIPR004000. Actin-related.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PANTHERPTHR11937. PTHR11937. 1 hit.
PfamPF00022. Actin. 1 hit.
PF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSPR00190. ACTIN.
SMARTSM00268. ACTIN. 1 hit.
SM00248. ANK. 6 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
PROSITEPS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi653781.
NextBio123637.
PROP0CG39.

Entry information

Entry namePOTEJ_HUMAN
AccessionPrimary (citable) accession number: P0CG39
Entry history
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: July 13, 2010
Last modified: April 16, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 2

Human chromosome 2: entries, gene names and cross-references to MIM