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P0CG39

- POTEJ_HUMAN

UniProt

P0CG39 - POTEJ_HUMAN

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Protein
POTE ankyrin domain family member J
Gene
POTEJ
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GO - Biological processi

  1. retina homeostasis Source: UniProt
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiP0CG39.

Names & Taxonomyi

Protein namesi
Recommended name:
POTE ankyrin domain family member J
Gene namesi
Name:POTEJ
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:37094. POTEJ.

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: UniProt
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165697368.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10381038POTE ankyrin domain family member J
PRO_0000395414Add
BLAST

Proteomic databases

MaxQBiP0CG39.
PRIDEiP0CG39.

PTM databases

PhosphoSiteiP0CG39.

Expressioni

Gene expression databases

BgeeiP0CG39.

Organism-specific databases

HPAiHPA041264.
HPA042822.
HPA043260.

Interactioni

Protein-protein interaction databases

BioGridi576066. 4 interactions.
IntActiP0CG39. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliP0CG39.
SMRiP0CG39. Positions 10-327, 669-1038.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati135 – 16430ANK 1
Add
BLAST
Repeati168 – 19730ANK 2
Add
BLAST
Repeati201 – 23030ANK 3
Add
BLAST
Repeati234 – 26330ANK 4
Add
BLAST
Repeati267 – 29630ANK 5
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni666 – 1038373Actin-like
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili605 – 66157 Reviewed prediction
Add
BLAST

Sequence similaritiesi

In the N-terminal section; belongs to the POTE family.
In the C-terminal section; belongs to the actin family.
Contains 5 ANK repeats.

Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

HOGENOMiHOG000115614.
KOiK17299.
OMAiNENCERI.
OrthoDBiEOG7FBRHS.
PhylomeDBiP0CG39.
TreeFamiTF354237.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR004000. Actin-related.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF00022. Actin. 1 hit.
PF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
SM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0CG39-1 [UniParc]FASTAAdd to Basket

« Hide

MVAEVDSMPA ASSVKKPFVL RSKMGKWCRH CFPCCRGSGK SNVGTSGDQD     50
DSTMKTLRSK MGKWCCHCFP CCRGSGKSNV GAWGDYDDSA FVEPRYHVRR 100
EDLDKLHRAA WWGKVARKDL IVMLRDTDVN KQDKQKRTAL HLASANGNSG 150
VVKLLLDRRC QLNVLDNKKR TALTKAVQCQ EDECALMLLE HGTDPNIPDE 200
YGNTTLHYAI YNEDKLMAKA LLLYGADIES KNKHGLTPLL LGVHEQKQQV 250
VKFLIKKKAN LNALDRYGRT ALILAVCCGS ASIVSLLLEQ NIDVSSQDLS 300
GQTAREYAVS SHHHVICQLL SDYKEKQMLK ISSENSNPEQ DLKLTSEEES 350
QRFKGSENSQ PEKMSQEPEI NKDGDREVEE EMKKHESNNV GLLENLSNGV 400
TAGNGDDGLI PQRKSRTPEN QQFPDNESEE YHRICELVSD YKEKQMPKYS 450
SENSNPEQDL KLTSEEESQR LKGSENGQPE KRSQEPEINK DGDRELENFM 500
AIEEMKKHGS THVGFPENLT NGATAGNGDD GLIPPRKSRT PESQQFPDTE 550
NEEYHSDEQN DTQKQFCEEQ NTGILHDEIL IHEEKQIEVV EKMNSELSLS 600
CKKERDFLHE NSMLREEIAM LRLELDTMKH QSQLRKKKYL EDIESVKKKN 650
DNLLKALQLN ELTMDDDTAV LVIDNGSGMC KAGFAGDDAP RAVFPSIVGC 700
PRQQGMMGGM HQKESYVGKE AQSKRGILTL KYPMEHGIIT NWDDMEKIWH 750
HTFYNELRVA PEEHPILLTE APLNPKANRE KMTQIMFETF NTPAMYVAIQ 800
AMLSLYTSGR TTGIVMDSGD GVTHTVPIYD GNALPHATLR LDLAGRELTD 850
YLMKILTERG YRFTTMAERE IVRDIKEKLC YVALDFEQEM AMVASSSSLE 900
KSYELPDGQV ITISNEWFRC PEALFQPCFL GMESCGIHET TFNSIMKSDV 950
DIRKDLYTNT VLSGGTTMYP GMAHRMQKEI AALAPSMMKI RIIAPPKRKY 1000
SVWVGGSILA SLSTFQQMWI SKQEYDESGP SIVHRKCF 1038
Length:1,038
Mass (Da):117,390
Last modified:July 13, 2010 - v1
Checksum:iFFDFF97D149A0899
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC140481 Genomic DNA. No translation available.
CCDSiCCDS59432.1.
RefSeqiNP_001264012.1. NM_001277083.1.
UniGeneiHs.558829.

Genome annotation databases

EnsembliENST00000409602; ENSP00000387176; ENSG00000222038.
GeneIDi653781.
KEGGihsa:653781.
UCSCiuc021vor.2. human.

Polymorphism databases

DMDMi300681052.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC140481 Genomic DNA. No translation available.
CCDSi CCDS59432.1.
RefSeqi NP_001264012.1. NM_001277083.1.
UniGenei Hs.558829.

3D structure databases

ProteinModelPortali P0CG39.
SMRi P0CG39. Positions 10-327, 669-1038.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 576066. 4 interactions.
IntActi P0CG39. 1 interaction.

PTM databases

PhosphoSitei P0CG39.

Polymorphism databases

DMDMi 300681052.

Proteomic databases

MaxQBi P0CG39.
PRIDEi P0CG39.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000409602 ; ENSP00000387176 ; ENSG00000222038 .
GeneIDi 653781.
KEGGi hsa:653781.
UCSCi uc021vor.2. human.

Organism-specific databases

CTDi 653781.
GeneCardsi GC02P131370.
HGNCi HGNC:37094. POTEJ.
HPAi HPA041264.
HPA042822.
HPA043260.
neXtProti NX_P0CG39.
PharmGKBi PA165697368.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000115614.
KOi K17299.
OMAi NENCERI.
OrthoDBi EOG7FBRHS.
PhylomeDBi P0CG39.
TreeFami TF354237.

Enzyme and pathway databases

SignaLinki P0CG39.

Miscellaneous databases

GenomeRNAii 653781.
NextBioi 123637.
PROi P0CG39.

Gene expression databases

Bgeei P0CG39.

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
InterProi IPR004000. Actin-related.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view ]
Pfami PF00022. Actin. 1 hit.
PF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
[Graphical view ]
PRINTSi PR00190. ACTIN.
SMARTi SM00268. ACTIN. 1 hit.
SM00248. ANK. 6 hits.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
PROSITEi PS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiPOTEJ_HUMAN
AccessioniPrimary (citable) accession number: P0CG39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: July 13, 2010
Last modified: September 3, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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