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P0CG20

- PRR35_HUMAN

UniProt

P0CG20 - PRR35_HUMAN

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Protein

Proline-rich protein 35

Gene

PRR35

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Proline-rich protein 35
Alternative name(s):
Uncharacterized protein RJD1
Gene namesi
Name:PRR35
Synonyms:C16orf11
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 16

Organism-specific databases

HGNCiHGNC:14139. PRR35.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25524.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 571571Proline-rich protein 35PRO_0000326184Add
BLAST

Proteomic databases

PRIDEiP0CG20.

PTM databases

PhosphoSiteiP0CG20.

Expressioni

Gene expression databases

BgeeiP0CG20.

Structurei

3D structure databases

ProteinModelPortaliP0CG20.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi83 – 401319Pro-richAdd
BLAST

Phylogenomic databases

GeneTreeiENSGT00530000063870.
HOGENOMiHOG000089960.
InParanoidiP0CG20.
OMAiGSCRVGT.
OrthoDBiEOG7BP82D.
PhylomeDBiP0CG20.
TreeFamiTF331381.

Sequencei

Sequence statusi: Complete.

P0CG20-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSREAGSCRV GTGARARSRK PKKPHYIPRP WGKPYNYKCF QCPFTCLEKS
60 70 80 90 100
HLYNHMKYSL CKDSLSLLLD SPDWACRRGS TTPRPHAPTP DRPGESDPGR
110 120 130 140 150
QPQGARPTGA APAPDLVVAD IHSLHCGGGP KSRAKGSPGP PPPVARATRK
160 170 180 190 200
GPGPSGLLPE SWKPGMGGDP RGVGAGDMAS AGPEGSVPCY PPPAPGEFPE
210 220 230 240 250
AHSLHLSLLG VNYPLSPGLF SYLGPSLAAA AHVPFLASAS PLLPPATAFP
260 270 280 290 300
AVQPPQRPTP APRLYYPLLL EHTLGLPAGK AALAKAPVSP RSPSGTPAPG
310 320 330 340 350
LLKVPVPGLG PWPRVTPRDP GQEGELERAA QSDPRRRLSL GSRLELPKAS
360 370 380 390 400
PSLTRFCSRS SLPTGSSVML WPEDGDPGGP ETPGPEGPLP LQPRGPVPGS
410 420 430 440 450
PEHVGEDLTR ALGDYARVEQ RLGQLGPAGG LAPRPLREQL GKIRLELLTI
460 470 480 490 500
HQALEQAVRP PDAPLDLSVK RAPAKGPQAL GEAWGRPELG PVLTGGTPEP
510 520 530 540 550
PGMLGPAAPQ PFSGHTTKCE ADSSVPPPGL PLAAPDDPVI PGSGWGTCVA
560 570
TRSSQTPEAV CGLQSPQGAE V
Length:571
Mass (Da):59,354
Last modified:June 15, 2010 - v1
Checksum:i7F15F84F05FF460E
GO

Sequence cautioni

The sequence AAK61234.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006464 Genomic DNA. Translation: AAK61234.1. Sequence problems.
Z97986 Genomic DNA. Translation: CAX15189.1.
CH471112 Genomic DNA. Translation: EAW85802.1.
BC016613 mRNA. Translation: AAH16613.1.
CCDSiCCDS45365.1.
RefSeqiNP_660313.1. NM_145270.2.
XP_005255187.1. XM_005255130.2.
XP_006720912.1. XM_006720849.1.
UniGeneiHs.632220.

Genome annotation databases

EnsembliENST00000409413; ENSP00000386499; ENSG00000161992.
GeneIDi146325.
KEGGihsa:146325.
UCSCiuc002chk.3. human.

Polymorphism databases

DMDMi298351619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006464 Genomic DNA. Translation: AAK61234.1 . Sequence problems.
Z97986 Genomic DNA. Translation: CAX15189.1 .
CH471112 Genomic DNA. Translation: EAW85802.1 .
BC016613 mRNA. Translation: AAH16613.1 .
CCDSi CCDS45365.1.
RefSeqi NP_660313.1. NM_145270.2.
XP_005255187.1. XM_005255130.2.
XP_006720912.1. XM_006720849.1.
UniGenei Hs.632220.

3D structure databases

ProteinModelPortali P0CG20.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei P0CG20.

Polymorphism databases

DMDMi 298351619.

Proteomic databases

PRIDEi P0CG20.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000409413 ; ENSP00000386499 ; ENSG00000161992 .
GeneIDi 146325.
KEGGi hsa:146325.
UCSCi uc002chk.3. human.

Organism-specific databases

CTDi 146325.
GeneCardsi GC16P000610.
HGNCi HGNC:14139. PRR35.
neXtProti NX_P0CG20.
PharmGKBi PA25524.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00530000063870.
HOGENOMi HOG000089960.
InParanoidi P0CG20.
OMAi GSCRVGT.
OrthoDBi EOG7BP82D.
PhylomeDBi P0CG20.
TreeFami TF331381.

Miscellaneous databases

GenomeRNAii 146325.
NextBioi 85330.

Gene expression databases

Bgeei P0CG20.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."
    Daniels R.J., Peden J.F., Lloyd C., Horsley S.W., Clark K., Tufarelli C., Kearney L., Buckle V.J., Doggett N.A., Flint J., Higgs D.R.
    Hum. Mol. Genet. 10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The sequence and analysis of duplication-rich human chromosome 16."
    Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.
    , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
    Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Eye.

Entry informationi

Entry nameiPRR35_HUMAN
AccessioniPrimary (citable) accession number: P0CG20
Secondary accession number(s): B8ZZ27
, Q8N233, Q96AX3, Q96S23
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: October 29, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM

External Data

Dasty 3