Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P0CG20 (PRR35_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proline-rich protein 35
Alternative name(s):
Uncharacterized protein RJD1
Gene names
Name:PRR35
Synonyms:C16orf11
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length571 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence caution

The sequence AAK61234.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 571571Proline-rich protein 35
PRO_0000326184

Regions

Compositional bias83 – 401319Pro-rich

Sequences

Sequence LengthMass (Da)Tools
P0CG20 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: 7F15F84F05FF460E

FASTA57159,354
        10         20         30         40         50         60 
MSREAGSCRV GTGARARSRK PKKPHYIPRP WGKPYNYKCF QCPFTCLEKS HLYNHMKYSL 

        70         80         90        100        110        120 
CKDSLSLLLD SPDWACRRGS TTPRPHAPTP DRPGESDPGR QPQGARPTGA APAPDLVVAD 

       130        140        150        160        170        180 
IHSLHCGGGP KSRAKGSPGP PPPVARATRK GPGPSGLLPE SWKPGMGGDP RGVGAGDMAS 

       190        200        210        220        230        240 
AGPEGSVPCY PPPAPGEFPE AHSLHLSLLG VNYPLSPGLF SYLGPSLAAA AHVPFLASAS 

       250        260        270        280        290        300 
PLLPPATAFP AVQPPQRPTP APRLYYPLLL EHTLGLPAGK AALAKAPVSP RSPSGTPAPG 

       310        320        330        340        350        360 
LLKVPVPGLG PWPRVTPRDP GQEGELERAA QSDPRRRLSL GSRLELPKAS PSLTRFCSRS 

       370        380        390        400        410        420 
SLPTGSSVML WPEDGDPGGP ETPGPEGPLP LQPRGPVPGS PEHVGEDLTR ALGDYARVEQ 

       430        440        450        460        470        480 
RLGQLGPAGG LAPRPLREQL GKIRLELLTI HQALEQAVRP PDAPLDLSVK RAPAKGPQAL 

       490        500        510        520        530        540 
GEAWGRPELG PVLTGGTPEP PGMLGPAAPQ PFSGHTTKCE ADSSVPPPGL PLAAPDDPVI 

       550        560        570 
PGSGWGTCVA TRSSQTPEAV CGLQSPQGAE V 

« Hide

References

[1]"Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."
Daniels R.J., Peden J.F., Lloyd C., Horsley S.W., Clark K., Tufarelli C., Kearney L., Buckle V.J., Doggett N.A., Flint J., Higgs D.R.
Hum. Mol. Genet. 10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The sequence and analysis of duplication-rich human chromosome 16."
Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. expand/collapse author list , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006464 Genomic DNA. Translation: AAK61234.1. Sequence problems.
Z97986 Genomic DNA. Translation: CAX15189.1.
CH471112 Genomic DNA. Translation: EAW85802.1.
BC016613 mRNA. Translation: AAH16613.1.
CCDSCCDS45365.1.
RefSeqNP_660313.1. NM_145270.2.
XP_005255187.1. XM_005255130.2.
XP_006720912.1. XM_006720849.1.
UniGeneHs.632220.

3D structure databases

ProteinModelPortalP0CG20.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteP0CG20.

Polymorphism databases

DMDM298351619.

Proteomic databases

PRIDEP0CG20.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000409413; ENSP00000386499; ENSG00000161992.
GeneID146325.
KEGGhsa:146325.
UCSCuc002chk.3. human.

Organism-specific databases

CTD146325.
GeneCardsGC16P000610.
HGNCHGNC:14139. PRR35.
neXtProtNX_P0CG20.
PharmGKBPA25524.
GenAtlasSearch...

Phylogenomic databases

HOGENOMHOG000089960.
OMAGSCRVGT.
OrthoDBEOG7BP82D.
PhylomeDBP0CG20.
TreeFamTF331381.

Gene expression databases

BgeeP0CG20.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi146325.
NextBio85330.

Entry information

Entry namePRR35_HUMAN
AccessionPrimary (citable) accession number: P0CG20
Secondary accession number(s): B8ZZ27 expand/collapse secondary AC list , Q8N233, Q96AX3, Q96S23
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: July 9, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM