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P0CG20

- PRR35_HUMAN

UniProt

P0CG20 - PRR35_HUMAN

Protein

Proline-rich protein 35

Gene

PRR35

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (15 Jun 2010)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Proline-rich protein 35
    Alternative name(s):
    Uncharacterized protein RJD1
    Gene namesi
    Name:PRR35
    Synonyms:C16orf11
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 16

    Organism-specific databases

    HGNCiHGNC:14139. PRR35.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA25524.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 571571Proline-rich protein 35PRO_0000326184Add
    BLAST

    Proteomic databases

    PRIDEiP0CG20.

    PTM databases

    PhosphoSiteiP0CG20.

    Expressioni

    Gene expression databases

    BgeeiP0CG20.

    Structurei

    3D structure databases

    ProteinModelPortaliP0CG20.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi83 – 401319Pro-richAdd
    BLAST

    Phylogenomic databases

    HOGENOMiHOG000089960.
    OMAiGSCRVGT.
    OrthoDBiEOG7BP82D.
    PhylomeDBiP0CG20.
    TreeFamiTF331381.

    Sequencei

    Sequence statusi: Complete.

    P0CG20-1 [UniParc]FASTAAdd to Basket

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    MSREAGSCRV GTGARARSRK PKKPHYIPRP WGKPYNYKCF QCPFTCLEKS    50
    HLYNHMKYSL CKDSLSLLLD SPDWACRRGS TTPRPHAPTP DRPGESDPGR 100
    QPQGARPTGA APAPDLVVAD IHSLHCGGGP KSRAKGSPGP PPPVARATRK 150
    GPGPSGLLPE SWKPGMGGDP RGVGAGDMAS AGPEGSVPCY PPPAPGEFPE 200
    AHSLHLSLLG VNYPLSPGLF SYLGPSLAAA AHVPFLASAS PLLPPATAFP 250
    AVQPPQRPTP APRLYYPLLL EHTLGLPAGK AALAKAPVSP RSPSGTPAPG 300
    LLKVPVPGLG PWPRVTPRDP GQEGELERAA QSDPRRRLSL GSRLELPKAS 350
    PSLTRFCSRS SLPTGSSVML WPEDGDPGGP ETPGPEGPLP LQPRGPVPGS 400
    PEHVGEDLTR ALGDYARVEQ RLGQLGPAGG LAPRPLREQL GKIRLELLTI 450
    HQALEQAVRP PDAPLDLSVK RAPAKGPQAL GEAWGRPELG PVLTGGTPEP 500
    PGMLGPAAPQ PFSGHTTKCE ADSSVPPPGL PLAAPDDPVI PGSGWGTCVA 550
    TRSSQTPEAV CGLQSPQGAE V 571
    Length:571
    Mass (Da):59,354
    Last modified:June 15, 2010 - v1
    Checksum:i7F15F84F05FF460E
    GO

    Sequence cautioni

    The sequence AAK61234.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006464 Genomic DNA. Translation: AAK61234.1. Sequence problems.
    Z97986 Genomic DNA. Translation: CAX15189.1.
    CH471112 Genomic DNA. Translation: EAW85802.1.
    BC016613 mRNA. Translation: AAH16613.1.
    CCDSiCCDS45365.1.
    RefSeqiNP_660313.1. NM_145270.2.
    XP_005255187.1. XM_005255130.2.
    XP_006720912.1. XM_006720849.1.
    UniGeneiHs.632220.

    Genome annotation databases

    EnsembliENST00000409413; ENSP00000386499; ENSG00000161992.
    GeneIDi146325.
    KEGGihsa:146325.
    UCSCiuc002chk.3. human.

    Polymorphism databases

    DMDMi298351619.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006464 Genomic DNA. Translation: AAK61234.1 . Sequence problems.
    Z97986 Genomic DNA. Translation: CAX15189.1 .
    CH471112 Genomic DNA. Translation: EAW85802.1 .
    BC016613 mRNA. Translation: AAH16613.1 .
    CCDSi CCDS45365.1.
    RefSeqi NP_660313.1. NM_145270.2.
    XP_005255187.1. XM_005255130.2.
    XP_006720912.1. XM_006720849.1.
    UniGenei Hs.632220.

    3D structure databases

    ProteinModelPortali P0CG20.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei P0CG20.

    Polymorphism databases

    DMDMi 298351619.

    Proteomic databases

    PRIDEi P0CG20.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000409413 ; ENSP00000386499 ; ENSG00000161992 .
    GeneIDi 146325.
    KEGGi hsa:146325.
    UCSCi uc002chk.3. human.

    Organism-specific databases

    CTDi 146325.
    GeneCardsi GC16P000610.
    HGNCi HGNC:14139. PRR35.
    neXtProti NX_P0CG20.
    PharmGKBi PA25524.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000089960.
    OMAi GSCRVGT.
    OrthoDBi EOG7BP82D.
    PhylomeDBi P0CG20.
    TreeFami TF331381.

    Miscellaneous databases

    GenomeRNAii 146325.
    NextBioi 85330.

    Gene expression databases

    Bgeei P0CG20.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."
      Daniels R.J., Peden J.F., Lloyd C., Horsley S.W., Clark K., Tufarelli C., Kearney L., Buckle V.J., Doggett N.A., Flint J., Higgs D.R.
      Hum. Mol. Genet. 10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.
      , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
      Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Eye.

    Entry informationi

    Entry nameiPRR35_HUMAN
    AccessioniPrimary (citable) accession number: P0CG20
    Secondary accession number(s): B8ZZ27
    , Q8N233, Q96AX3, Q96S23
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: June 15, 2010
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 16
      Human chromosome 16: entries, gene names and cross-references to MIM

    External Data

    Dasty 3