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P0CG07 (SCRA_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Defensin-like protein A

Short name=AtSCRA
Alternative name(s):
S locus cysteine-rich-like protein A
S locus protein 11
Gene names
Name:SCRA
Synonyms:SCR1, SP11
Ordered Locus Names:At4g21364
ORF Names:T6K22
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length62 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Truncated and inactivated form of SCRA, a protein involved in male-mediated self-incompatibility when active. Most A.thaliana cultivars contain such an inactive form and thus, are self-fertiles. Ref.1 Ref.3 Ref.4 Ref.5

Subcellular location

Secreted By similarity.

Miscellaneous

By contrast to A.lyrata and A.halleri, self-incompatible species with full-length SCRA isoforms, A.thaliana is self-compatible with impaired SCRA protein.

Sequence similarities

Belongs to the DEFL family.

Ontologies

Keywords
   Biological processSelf-incompatibility
   Cellular componentSecreted
   DomainSignal
   PTMDisulfide bond
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processrejection of self pollen

Inferred from electronic annotation. Source: UniProtKB-KW

signal transduction

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2626 Potential
Chain27 – 6236Defensin-like protein A
PRO_0000394667

Amino acid modifications

Disulfide bond42 ↔ 52 By similarity

Experimental info

Mutagenesis56 – 627DAKKTLA → IAKNFRPSRPFECNCQTFDK GGICYCKKCLV: Confers male-driven self-incompatibility. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P0CG07 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: 863A76970BCF46A9

FASTA627,226
        10         20         30         40         50         60 
MRCVVLFMVS CLLIVLLINH FEEVEAQKWN KCFLRDIFPG KCEHDANAKL RCKEDDAKKT 


LA 

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References

« Hide 'large scale' references
[1]"Evolution of self-compatibility in Arabidopsis by a mutation in the male specificity gene."
Tsuchimatsu T., Suwabe K., Shimizu-Inatsugi R., Isokawa S., Pavlidis P., Stadler T., Suzuki G., Takayama S., Watanabe M., Shimizu K.K.
Nature 464:1342-1346(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, MUTAGENESIS OF 56-ASP--ALA-62.
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. expand/collapse author list , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]"Natural variation in expression of self-incompatibility in Arabidopsis thaliana: implications for the evolution of selfing."
Nasrallah M.E., Liu P., Sherman-Broyles S., Boggs N.A., Nasrallah J.B.
Proc. Natl. Acad. Sci. U.S.A. 101:16070-16074(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[4]"The transition to self-compatibility in Arabidopsis thaliana and evolution within S-haplotypes over 10 Myr."
Bechsgaard J.S., Castric V., Charlesworth D., Vekemans X., Schierup M.H.
Mol. Biol. Evol. 23:1741-1750(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[5]"Independent S-locus mutations caused self-fertility in Arabidopsis thaliana."
Boggs N.A., Nasrallah J.B., Nasrallah M.E.
PLoS Genet. 5:E1000426-E1000426(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.

Web resources

Protein Spotlight

Do it yourself - Issue 128 of May 2011

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL031187 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalP0CG07.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

TAIRAT4G21364.

Family and domain databases

InterProIPR010682. SCRL.
[Graphical view]
PfamPF06876. SCRL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSCRA_ARATH
AccessionPrimary (citable) accession number: P0CG07
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: February 19, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names