ID   INSL2_ECOLI             Reviewed;         370 AA.
AC   P0CF92; P08409; P11307; P76952; P77426; Q2MCH6; Q47051;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   RecName: Full=Putative transposase InsL for insertion sequence element IS186B;
GN   Name=insL2; OrderedLocusNames=b0582, JW0572;
OS   Escherichia coli (strain K12).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence
CC       IS186.
CC   -!- SIMILARITY: Belongs to the transposase 11 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB40781.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U82598; AAB40781.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC73683.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35223.1; -; Genomic_DNA.
DR   PIR; G65013; QQEC47.
DR   RefSeq; NP_414557.1; NC_000913.3.
DR   RefSeq; NP_415114.1; NC_000913.3.
DR   RefSeq; NP_416895.2; NC_000913.3.
DR   RefSeq; WP_001300563.1; NZ_STEB01000093.1.
DR   AlphaFoldDB; P0CF92; -.
DR   EnsemblBacteria; AAC73683; AAC73683; b0582.
DR   GeneID; 34758144; -.
DR   GeneID; 944754; -.
DR   GeneID; 945200; -.
DR   GeneID; 946896; -.
DR   KEGG; ecj:JW0572; -.
DR   KEGG; eco:b0016; -.
DR   KEGG; eco:b0582; -.
DR   KEGG; eco:b2394; -.
DR   EchoBASE; EB4754; -.
DR   HOGENOM; CLU_049434_1_0_6; -.
DR   InParanoid; P0CF92; -.
DR   OMA; IVRVYWR; -.
DR   OrthoDB; 5889367at2; -.
DR   BioCyc; EcoCyc:MONOMER0-4232; -.
DR   PRO; PR:P0CF92; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR047952; Transpos_IS4.
DR   InterPro; IPR002559; Transposase_11.
DR   NCBIfam; NF033592; transpos_IS4_1; 1.
DR   PANTHER; PTHR33258; TRANSPOSASE INSL FOR INSERTION SEQUENCE ELEMENT IS186A-RELATED; 1.
DR   PANTHER; PTHR33258:SF1; TRANSPOSASE INSL FOR INSERTION SEQUENCE ELEMENT IS186A-RELATED; 1.
DR   Pfam; PF01609; DDE_Tnp_1; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW   Transposition.
FT   CHAIN           1..370
FT                   /note="Putative transposase InsL for insertion sequence
FT                   element IS186B"
FT                   /id="PRO_0000394137"
SQ   SEQUENCE   370 AA;  40909 MW;  FDD2041F5F3D7F03 CRC64;
     MNYSHDNWSA ILAHIGKPEE LDTSARNAGA LTRRREIRDA ATLLRLGLAY GPGGMSLREV
     TAWAQLHDVA TLSDVALLKR LRNAADWFGI LAAQTLAVRA AVTGCTSGKR LRLVDGTAIS
     APGGGSAEWR LHMGYDPHTC QFTDFELTDS RDAERLDRFA QTADEIRIAD RGFGSRPECI
     RSLAFGEADY IVRVHWRGLR WLTAEGMRFD MMGFLRGLDC GKNGETTVMI GNSGNKKAGA
     PFPARLIAVS LPPEKALISK TRLLSENRRK GRVVQAETLE AAGHVLLLTS LPEDEYSAEQ
     VADCYRLRWQ IELAFKRLKS LLHLDALRAK EPELAKAWIF ANLLAAFLID DIIQPSLDFP
     PRSAGSEKKN
//