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P0CF92

- INSL2_ECOLI

UniProt

P0CF92 - INSL2_ECOLI

Protein

Putative transposase InsL for insertion sequence element IS186B

Gene

insL2

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (18 May 2010)
      Previous versions | rss
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    Functioni

    Involved in the transposition of the insertion sequence IS186.

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. transposase activity Source: InterPro

    GO - Biological processi

    1. transposition, DNA-mediated Source: InterPro

    Keywords - Biological processi

    DNA recombination, Transposition

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciEcoCyc:MONOMER0-4232.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative transposase InsL for insertion sequence element IS186B
    Gene namesi
    Name:insL2
    Ordered Locus Names:b0582, JW0572
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG40012. insL2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 370370Putative transposase InsL for insertion sequence element IS186BPRO_0000394137Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP0CF92.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the transposase 11 family.Curated

    Family and domain databases

    Gene3Di3.90.350.10. 1 hit.
    InterProiIPR012337. RNaseH-like_dom.
    IPR002559. Transposase_11.
    IPR014736. Transposase_Tn5-like_core.
    [Graphical view]
    PfamiPF01609. DDE_Tnp_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF53098. SSF53098. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0CF92-1 [UniParc]FASTAAdd to Basket

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    MNYSHDNWSA ILAHIGKPEE LDTSARNAGA LTRRREIRDA ATLLRLGLAY    50
    GPGGMSLREV TAWAQLHDVA TLSDVALLKR LRNAADWFGI LAAQTLAVRA 100
    AVTGCTSGKR LRLVDGTAIS APGGGSAEWR LHMGYDPHTC QFTDFELTDS 150
    RDAERLDRFA QTADEIRIAD RGFGSRPECI RSLAFGEADY IVRVHWRGLR 200
    WLTAEGMRFD MMGFLRGLDC GKNGETTVMI GNSGNKKAGA PFPARLIAVS 250
    LPPEKALISK TRLLSENRRK GRVVQAETLE AAGHVLLLTS LPEDEYSAEQ 300
    VADCYRLRWQ IELAFKRLKS LLHLDALRAK EPELAKAWIF ANLLAAFLID 350
    DIIQPSLDFP PRSAGSEKKN 370
    Length:370
    Mass (Da):40,909
    Last modified:May 18, 2010 - v1
    Checksum:iFDD2041F5F3D7F03
    GO

    Sequence cautioni

    The sequence AAB40781.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U82598 Genomic DNA. Translation: AAB40781.1. Different initiation.
    U00096 Genomic DNA. Translation: AAC73683.1.
    AP009048 Genomic DNA. Translation: BAA35223.1.
    PIRiG65013. QQEC47.
    RefSeqiNP_414557.1. NC_000913.3.
    NP_415114.1. NC_000913.3.
    NP_416895.2. NC_000913.3.
    YP_488322.1. NC_007779.1.
    YP_488870.1. NC_007779.1.
    YP_490635.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC73683; AAC73683; b0582.
    BAA35223; BAA35223; BAA35223.
    GeneIDi12930191.
    12930725.
    12931716.
    944754.
    945200.
    946896.
    KEGGiecj:Y75_p0016.
    ecj:Y75_p0570.
    ecj:Y75_p2360.
    eco:b0016.
    eco:b0582.
    eco:b2394.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U82598 Genomic DNA. Translation: AAB40781.1 . Different initiation.
    U00096 Genomic DNA. Translation: AAC73683.1 .
    AP009048 Genomic DNA. Translation: BAA35223.1 .
    PIRi G65013. QQEC47.
    RefSeqi NP_414557.1. NC_000913.3.
    NP_415114.1. NC_000913.3.
    NP_416895.2. NC_000913.3.
    YP_488322.1. NC_007779.1.
    YP_488870.1. NC_007779.1.
    YP_490635.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P0CF92.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC73683 ; AAC73683 ; b0582 .
    BAA35223 ; BAA35223 ; BAA35223 .
    GeneIDi 12930191.
    12930725.
    12931716.
    944754.
    945200.
    946896.
    KEGGi ecj:Y75_p0016.
    ecj:Y75_p0570.
    ecj:Y75_p2360.
    eco:b0016.
    eco:b0582.
    eco:b2394.

    Organism-specific databases

    EchoBASEi EB4754.
    EcoGenei EG40012. insL2.

    Enzyme and pathway databases

    BioCyci EcoCyc:MONOMER0-4232.

    Family and domain databases

    Gene3Di 3.90.350.10. 1 hit.
    InterProi IPR012337. RNaseH-like_dom.
    IPR002559. Transposase_11.
    IPR014736. Transposase_Tn5-like_core.
    [Graphical view ]
    Pfami PF01609. DDE_Tnp_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53098. SSF53098. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiINSL2_ECOLI
    AccessioniPrimary (citable) accession number: P0CF92
    Secondary accession number(s): P08409
    , P11307, P76952, P77426, Q2MCH6, Q47051
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 18, 2010
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome, Transposable element

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3