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Protein

Putative transposase InsL for insertion sequence element IS186B

Gene

insL2

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the transposition of the insertion sequence IS186.

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. transposase activity Source: InterPro

GO - Biological processi

  1. transposition, DNA-mediated Source: InterPro
Complete GO annotation...

Keywords - Biological processi

DNA recombination, Transposition

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-4232.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transposase InsL for insertion sequence element IS186B
Gene namesi
Name:insL2
Ordered Locus Names:b0582, JW0572
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318 Componenti: Chromosome UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG40012. insL2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 370370Putative transposase InsL for insertion sequence element IS186BPRO_0000394137Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP0CF92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transposase 11 family.Curated

Phylogenomic databases

InParanoidiP0CF92.

Family and domain databases

Gene3Di3.90.350.10. 1 hit.
InterProiIPR012337. RNaseH-like_dom.
IPR002559. Transposase_11.
IPR014736. Transposase_Tn5-like_core.
[Graphical view]
PfamiPF01609. DDE_Tnp_1. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

P0CF92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYSHDNWSA ILAHIGKPEE LDTSARNAGA LTRRREIRDA ATLLRLGLAY
60 70 80 90 100
GPGGMSLREV TAWAQLHDVA TLSDVALLKR LRNAADWFGI LAAQTLAVRA
110 120 130 140 150
AVTGCTSGKR LRLVDGTAIS APGGGSAEWR LHMGYDPHTC QFTDFELTDS
160 170 180 190 200
RDAERLDRFA QTADEIRIAD RGFGSRPECI RSLAFGEADY IVRVHWRGLR
210 220 230 240 250
WLTAEGMRFD MMGFLRGLDC GKNGETTVMI GNSGNKKAGA PFPARLIAVS
260 270 280 290 300
LPPEKALISK TRLLSENRRK GRVVQAETLE AAGHVLLLTS LPEDEYSAEQ
310 320 330 340 350
VADCYRLRWQ IELAFKRLKS LLHLDALRAK EPELAKAWIF ANLLAAFLID
360 370
DIIQPSLDFP PRSAGSEKKN
Length:370
Mass (Da):40,909
Last modified:May 18, 2010 - v1
Checksum:iFDD2041F5F3D7F03
GO

Sequence cautioni

The sequence AAB40781.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40781.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73683.1.
AP009048 Genomic DNA. Translation: BAA35223.1.
PIRiG65013. QQEC47.
RefSeqiNP_414557.1. NC_000913.3.
NP_415114.1. NC_000913.3.
NP_416895.2. NC_000913.3.
YP_488322.1. NC_007779.1.
YP_488870.1. NC_007779.1.
YP_490635.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC73683; AAC73683; b0582.
BAA35223; BAA35223; BAA35223.
GeneIDi12930191.
12930725.
12931716.
944754.
945200.
946896.
KEGGiecj:Y75_p0016.
ecj:Y75_p0570.
ecj:Y75_p2360.
eco:b0016.
eco:b0582.
eco:b2394.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40781.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73683.1.
AP009048 Genomic DNA. Translation: BAA35223.1.
PIRiG65013. QQEC47.
RefSeqiNP_414557.1. NC_000913.3.
NP_415114.1. NC_000913.3.
NP_416895.2. NC_000913.3.
YP_488322.1. NC_007779.1.
YP_488870.1. NC_007779.1.
YP_490635.1. NC_007779.1.

3D structure databases

ProteinModelPortaliP0CF92.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73683; AAC73683; b0582.
BAA35223; BAA35223; BAA35223.
GeneIDi12930191.
12930725.
12931716.
944754.
945200.
946896.
KEGGiecj:Y75_p0016.
ecj:Y75_p0570.
ecj:Y75_p2360.
eco:b0016.
eco:b0582.
eco:b2394.

Organism-specific databases

EchoBASEiEB4754.
EcoGeneiEG40012. insL2.

Phylogenomic databases

InParanoidiP0CF92.

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-4232.

Family and domain databases

Gene3Di3.90.350.10. 1 hit.
InterProiIPR012337. RNaseH-like_dom.
IPR002559. Transposase_11.
IPR014736. Transposase_Tn5-like_core.
[Graphical view]
PfamiPF01609. DDE_Tnp_1. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiINSL2_ECOLI
AccessioniPrimary (citable) accession number: P0CF92
Secondary accession number(s): P08409
, P11307, P76952, P77426, Q2MCH6, Q47051
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: May 18, 2010
Last modified: January 7, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome, Transposable element

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.