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Protein

Putative transposase InsD for insertion element IS2E

Gene

insD8

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Involved in the transposition of the insertion sequence IS2.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA recombination, Transposition

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6836-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transposase InsD for insertion element IS2E
Gene namesi
Name:insD8
Ordered Locus Names:b1578, JW1570
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG40004. insD8.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218Putative transposase InsD for insertion element IS2EPRO_0000393579Add
BLAST

Proteomic databases

PaxDbiP0CF60.
PRIDEiP0CF60.

Interactioni

Protein-protein interaction databases

STRINGi511145.b4273.

Structurei

3D structure databases

ProteinModelPortaliP0CF60.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 206184Integrase catalyticPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 integrase catalytic domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108MVM. Bacteria.
ENOG410Z4Y8. LUCA.
InParanoidiP0CF60.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR001584. Integrase_cat-core.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00665. rve. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
PROSITEiPS50994. INTEGRASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0CF60-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAINAKRVY RIMRQNALLL ERKPAVPPSK RAHTGRVAVK ESNQRWCSDG
60 70 80 90 100
FEFCCDNGER LRVTFALDCC DREALHWAVT TGGFNSETVQ DVMLGAVERR
110 120 130 140 150
FGNDLPSSPV EWLTDNGSCY RANETRQFAR MLGLEPKNTA VRSPESNGIA
160 170 180 190 200
ESFVKTIKRD YISIMPKPDG LTAAKNLAEA FEHYNEWHPH SALGYRSPRE
210
YLRQRACNGL SDNRCLEI
Length:218
Mass (Da):24,724
Last modified:April 20, 2010 - v1
Checksum:i37C547ABD90AD05C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAA15283.2.

Genome annotation databases

EnsemblBacteriaiBAA15283; BAA15283; BAA15283.
KEGGiecj:JW1570.
PATRICi48662470. VBIEscCol107702_1595.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAA15283.2.

3D structure databases

ProteinModelPortaliP0CF60.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi511145.b4273.

Proteomic databases

PaxDbiP0CF60.
PRIDEiP0CF60.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA15283; BAA15283; BAA15283.
KEGGiecj:JW1570.
PATRICi48662470. VBIEscCol107702_1595.

Organism-specific databases

EcoGeneiEG40004. insD8.

Phylogenomic databases

eggNOGiENOG4108MVM. Bacteria.
ENOG410Z4Y8. LUCA.
InParanoidiP0CF60.

Enzyme and pathway databases

BioCyciEcoCyc:G6836-MONOMER.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR001584. Integrase_cat-core.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00665. rve. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
PROSITEiPS50994. INTEGRASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiINSD8_ECOLI
AccessioniPrimary (citable) accession number: P0CF60
Secondary accession number(s): P0C5W4
, P19777, P76167, P76916, P77033, Q79EJ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 11, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. IS2E is a partial IS2 sequence which lacks the N-terminal 83 residues of InsD. Locus b1578 is not annotated in the MG1655 genome and b1578/JW1570 is probably not expressed.Curated

Keywords - Technical termi

Complete proteome, Reference proteome, Transposable element

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.