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P0CF22 (YI167_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative truncated L-serine dehydratase SDL1

EC=4.3.1.17
Alternative name(s):
L-serine deaminase homolog 1
Gene names
Name:SDL1
Synonyms:SDH1
Ordered Locus Names:YIL167W
ORF Names:YI9402.08B
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Catalytic activity

L-serine = pyruvate + NH3.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Carbohydrate biosynthesis; gluconeogenesis.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the serine/threonine dehydratase family.

Caution

Could be the product of a pseudogene. This is the C-terminal part of L-serine dehydratase. Strain S288c has a stop codon in position 128, which disrupts the gene coding for this protein and produces two ORFs YIL167W and YIL168W. A contiguous sequence for L-serine dehydratase can be found in other strain backgrounds (AC P0CF23).

Ontologies

Keywords
   Biological processGluconeogenesis
   Cellular componentCytoplasm
   LigandPyridoxal phosphate
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

serine family amino acid metabolic process

Inferred from sequence or structural similarity PubMed 2194168. Source: SGD

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionL-serine ammonia-lyase activity

Inferred from sequence or structural similarity PubMed 2194168. Source: SGD

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 210210Putative truncated L-serine dehydratase SDL1
PRO_0000393394

Sequences

Sequence LengthMass (Da)Tools
P0CF22 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 2D731889214FFB7E

FASTA21022,812
        10         20         30         40         50         60 
MAQESQHGSK TLYVHPFDNE TIWEGHSTIV DEIIEQLKEN DISLPRVKAL VCSVGGGGLF 

        70         80         90        100        110        120 
SGIIKGLDRN QLAEKIPVVA VETAGCDVLN KSLKKGSPVT LEKLTSVATS LASPYIASFA 

       130        140        150        160        170        180 
FESFNKYGCK SVVLSDQDVL ATCLRYADDY NFIVEPACGA SLHLCYHPEI LEDILEQKIY 

       190        200        210 
EDDIVIIIAC GGSCMTYEDL VKASSTLNVS 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IX."
Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D., Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E., Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C. expand/collapse author list , Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:84-87(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z46921 Genomic DNA. Translation: CAA87025.1.
BK006942 Genomic DNA. No translation available.
PIRS12731.

3D structure databases

ProteinModelPortalP0CF22.
SMRP0CF22. Positions 12-200.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

SGDS000001429. SDL1.

Phylogenomic databases

OrthoDBEOG7KDFMQ.

Enzyme and pathway databases

UniPathwayUPA00138.

Family and domain databases

InterProIPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
[Graphical view]
PfamPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMSSF53686. SSF53686. 1 hit.
ProtoNetSearch...

Entry information

Entry nameYI167_YEAST
AccessionPrimary (citable) accession number: P0CF22
Secondary accession number(s): P17324 expand/collapse secondary AC list , P40443, P40444, Q6Q579
Entry history
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 19, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IX

Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways