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Protein

Putative truncated L-serine dehydratase SDL1

Gene

SDL1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Catalytic activityi

L-serine = pyruvate + NH3.

Cofactori

Pathway: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

GO - Molecular functioni

  • L-serine ammonia-lyase activity Source: SGD

GO - Biological processi

  • gluconeogenesis Source: UniProtKB-UniPathway
  • serine family amino acid metabolic process Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Gluconeogenesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative truncated L-serine dehydratase SDL1 (EC:4.3.1.17)
Alternative name(s):
L-serine deaminase homolog 1
Gene namesi
Name:SDL1
Synonyms:SDH1
Ordered Locus Names:YIL167W
ORF Names:YI9402.08B
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome IX

Organism-specific databases

SGDiS000001429. SDL1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210Putative truncated L-serine dehydratase SDL1PRO_0000393394Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP0CF22.
SMRiP0CF22. Positions 12-200.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiP0CF22.
OrthoDBiEOG7KDFMQ.

Family and domain databases

InterProiIPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.

Sequencei

Sequence statusi: Complete.

P0CF22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQESQHGSK TLYVHPFDNE TIWEGHSTIV DEIIEQLKEN DISLPRVKAL
60 70 80 90 100
VCSVGGGGLF SGIIKGLDRN QLAEKIPVVA VETAGCDVLN KSLKKGSPVT
110 120 130 140 150
LEKLTSVATS LASPYIASFA FESFNKYGCK SVVLSDQDVL ATCLRYADDY
160 170 180 190 200
NFIVEPACGA SLHLCYHPEI LEDILEQKIY EDDIVIIIAC GGSCMTYEDL
210
VKASSTLNVS
Length:210
Mass (Da):22,812
Last modified:April 20, 2010 - v1
Checksum:i2D731889214FFB7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46921 Genomic DNA. Translation: CAA87025.1.
BK006942 Genomic DNA. No translation available.
PIRiS12731.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46921 Genomic DNA. Translation: CAA87025.1.
BK006942 Genomic DNA. No translation available.
PIRiS12731.

3D structure databases

ProteinModelPortaliP0CF22.
SMRiP0CF22. Positions 12-200.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

SGDiS000001429. SDL1.

Phylogenomic databases

InParanoidiP0CF22.
OrthoDBiEOG7KDFMQ.

Enzyme and pathway databases

UniPathwayiUPA00138.

Family and domain databases

InterProiIPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiYI167_YEAST
AccessioniPrimary (citable) accession number: P0CF22
Secondary accession number(s): P17324
, P40443, P40444, Q6Q579
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: April 20, 2010
Last modified: January 7, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. This is the C-terminal part of L-serine dehydratase. Strain S288c has a stop codon in position 128, which disrupts the gene coding for this protein and produces two ORFs YIL167W and YIL168W. A contiguous sequence for L-serine dehydratase can be found in other strain backgrounds (AC P0CF23).Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.