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Protein

Putative truncated L-serine dehydratase SDL1

Gene

SDL1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Catalytic activityi

L-serine = pyruvate + NH3.

Cofactori

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

GO - Molecular functioni

  • L-serine ammonia-lyase activity Source: SGD

GO - Biological processi

  • gluconeogenesis Source: UniProtKB-UniPathway
  • serine family amino acid metabolic process Source: SGD

Keywordsi

Molecular functionLyase
Biological processGluconeogenesis
LigandPyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative truncated L-serine dehydratase SDL1 (EC:4.3.1.17)
Alternative name(s):
L-serine deaminase homolog 1
Gene namesi
Name:SDL1
Synonyms:SDH1
Ordered Locus Names:YIL167W
ORF Names:YI9402.08B
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Organism-specific databases

SGDiS000001429. SDL1.

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003933941 – 210Putative truncated L-serine dehydratase SDL1Add BLAST210

Structurei

3D structure databases

ProteinModelPortaliP0CF22.
SMRiP0CF22.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiP0CF22.
OrthoDBiEOG092C371W.

Family and domain databases

InterProiView protein in InterPro
IPR001926. PLP-dep.
IPR036052. Trypto_synt_PLP_dependent.
PfamiView protein in Pfam
PF00291. PALP. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.

Sequencei

Sequence statusi: Complete.

P0CF22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQESQHGSK TLYVHPFDNE TIWEGHSTIV DEIIEQLKEN DISLPRVKAL
60 70 80 90 100
VCSVGGGGLF SGIIKGLDRN QLAEKIPVVA VETAGCDVLN KSLKKGSPVT
110 120 130 140 150
LEKLTSVATS LASPYIASFA FESFNKYGCK SVVLSDQDVL ATCLRYADDY
160 170 180 190 200
NFIVEPACGA SLHLCYHPEI LEDILEQKIY EDDIVIIIAC GGSCMTYEDL
210
VKASSTLNVS
Length:210
Mass (Da):22,812
Last modified:April 20, 2010 - v1
Checksum:i2D731889214FFB7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46921 Genomic DNA. Translation: CAA87025.1.
PIRiS12731.

Similar proteinsi

Entry informationi

Entry nameiYI167_YEAST
AccessioniPrimary (citable) accession number: P0CF22
Secondary accession number(s): P17324
, P40443, P40444, Q6Q579
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 25, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene unlikely to encode a functional protein. This is the C-terminal part of L-serine dehydratase. Strain S288c has a stop codon in position 128, which disrupts the gene coding for this protein and produces two ORFs YIL167W and YIL168W. Because of that it is not part of the S.cerevisiae S288c complete/reference proteome set. A contiguous sequence for L-serine dehydratase can be found in other strain backgrounds (AC P0CF23).1 Publication

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IX
    Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names