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P0CF21 (YI168_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative truncated L-serine dehydratase YIL168W

EC=4.3.1.17
Gene names
Ordered Locus Names:YIL168W
ORF Names:YI9402.08A
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length127 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Catalytic activity

L-serine = pyruvate + NH3.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Carbohydrate biosynthesis; gluconeogenesis.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the serine/threonine dehydratase family.

Caution

Could be the product of a pseudogene. This is a truncated version of L-serine dehydratase. Strain S288c has a stop codon in position 128, which disrupts the gene coding for this protein and produces two ORFs YIL167W and YIL168W. A contiguous sequence for L-serine dehydratase can be found in other strain backgrounds (AC P0CF23).

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 127127Putative truncated L-serine dehydratase YIL168W
PRO_0000393393

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
P0CF21 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 3943C545FFE8B54C

FASTA12713,943
        10         20         30         40         50         60 
MEMTYYEKTP LIRQFLNNGK TNSWFYVKHE MLQPGGSFKS RGIGHLIRKS NEEALSEGSG 

        70         80         90        100        110        120 
KLAVFSSSGG NAGLAAATAC RSMALNCSVV VPKTTKPRMV KKIQSAGAKV IIHGDHWGEA 


DEYLRHE 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IX."
Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D., Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E., Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C. expand/collapse author list , Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:84-87(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z46921 Genomic DNA. Translation: CAA87024.1.
AY558344 Genomic DNA. Translation: AAS56670.1.
BK006942 Genomic DNA. No translation available.
PIRS12731.

3D structure databases

ProteinModelPortalP0CF21.
SMRP0CF21. Positions 9-121.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

SGDS000001430. YIL168W.

Phylogenomic databases

OrthoDBEOG7KDFMQ.

Enzyme and pathway databases

UniPathwayUPA00138.

Family and domain databases

InterProIPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
[Graphical view]
PfamPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMSSF53686. SSF53686. 1 hit.
PROSITEPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYI168_YEAST
AccessionPrimary (citable) accession number: P0CF21
Secondary accession number(s): P17324 expand/collapse secondary AC list , P40443, P40444, Q6Q579
Entry history
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: April 20, 2010
Last modified: January 22, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IX

Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways